| Not Yet Recruiting | This Clinical Trial Aims to Compare the Effectiveness of Two Intra-pulpal Cryotherapy Techniques-Endo-ice and NCT07264829 | Dow University of Health Sciences | N/A |
| Recruiting | Postoperative Pain After Root Canal Obturation Using Bioceramic and Calcium Hydroxide Sealers NCT07410780 | HITEC-Institute of Medical Sciences | N/A |
| Completed | Comparison of WaveOne and ProTaper Systems on Postoperative Pain in Irreversible Pulpitis Patients NCT07510490 | Armed Forces Institute of Dentistry, Pakistan | N/A |
| Recruiting | The Effect of Three Different Medications on Anesthetic Success and Postoperative Pain NCT06298383 | Cairo University | N/A |
| Not Yet Recruiting | To COMPARE the EFFECT of TWO INSTRUMENTATION TECHNIQUES on the INCIDENCE of POST-ENDODONTIC PAIN in PATIENTS U NCT06842251 | Urooj Fatima | N/A |
| Recruiting | Postoperative Pain After Pulpotomy in Children Using Calcium Silicate Cements With and Without Laser Therapy NCT07290049 | University of Fujairah | N/A |
| Recruiting | The Effect of XP-Endo Finisher Activation of Bioceramic Sealer on Postoperative Pain in Mandibular First Molar NCT06640231 | Future University in Egypt | N/A |
| Enrolling By Invitation | Comparison of Post-Operative Pain Occurrence After Single Visit Root Canal Treatment NCT06777381 | National Research Centre, Egypt | N/A |
| Recruiting | Regenerative Endodontic Therapy in Cases of Irreversible Pulpitis NCT06525844 | Shaheed Zulfiqar Ali Bhutto Medical University | N/A |
| Completed | Evaluation of Success of Complete Pulpotomy With Biodentine on Mature Permanent Single Rooted Teeth With Sympt NCT07112859 | HITEC-Institute of Medical Sciences | N/A |
| Completed | Comparative Evaluation of Postoperative Pain and Clinical Success NCT07133217 | Ege University | N/A |
| Unknown | Comparison of Anesthetic Efficacy of Mental Nerve Block Versus Inferior Alveolar Nerve Block in Mandibular Ant NCT06333730 | Prime Foundation | N/A |
| Completed | Effect of Dental Anxiety on Mandibular Anesthesia Success NCT07124273 | Kutahya Health Sciences University | N/A |
| Terminated | Combination of Buffered Anesthetic to Treat Mandibular Molars NCT06047366 | Indiana University | Phase 4 |
| Unknown | Anesthetic Efficacy of 1.8 ml Versus 3.6 ml of 4% Articaine Buccal Infiltration NCT06119139 | Cairo University | N/A |
| Completed | Evaluating the Combined Effect of Oral Premedications on Inferior Alveolar Nerve Block Effectiveness NCT07146997 | Zahoor khan | Phase 3 |
| Completed | Tobradex as Intracanal Medicament NCT07332936 | Umm Al-Qura University | N/A |
| Completed | Role of Propolis Endodontic Irrigant on Post-Operative Pain NCT05974748 | Dow University of Health Sciences | Phase 3 |
| Unknown | Efficacy of Pulpal Anesthesia and Patient Preference Using the Needle-less and Conventional Injection Techniqu NCT05724862 | Cairo University | N/A |
| Completed | Effect of Preoperative Tramadol and Naproxen Sodium on Post Operative Pain NCT05982392 | Dow University of Health Sciences | Phase 2 / Phase 3 |
| Unknown | Assessment of Pain and Treatment Success After VPT Versus RCT in Mature Permanent Mandibular Molars With SIP: NCT05681494 | Cairo University | N/A |
| Completed | Assessment of Local Anaesthesia Effectiveness in Symptomatic Irreversible Pulpitis NCT06862570 | 28 Military Dental Centre Lahore | Phase 2 |
| Completed | The Effectiveness of Single Antibiotic Paste Nitrofurantoin Versus Double Antibiotic Paste NCT05600023 | Altamash Institute of Dental Medicine | Phase 4 |
| Completed | Effect of Ultrasonic Activation of Bioceramic Sealer on Postoperative Pain in Lower Premolars NCT05289791 | Cairo University | N/A |
| Unknown | Effect of Cryotherapy Versus Post-operative Ibuprofen Medication on Post-operative Pain in Mandibular Molar Te NCT05341999 | Cairo University | Phase 1 |
| Unknown | Volume Increase Versus Supplemental 4% Articaine Buccal Infiltration on Mepivacaine Inferior Alveolar Nerve Bl NCT05238727 | Cairo University | N/A |
| Completed | Ethyl Chloride Versus 5% Lidocaine for Topical Anesthesia of Oral Mucosa NCT05306470 | Altamash Institute of Dental Medicine | N/A |
| Completed | Buffered vs. Unbuffered Local Anesthesia in Mandibular Molars Diagnosed With Symptomatic Irreversible Pulpitis NCT05227300 | Indiana University | Phase 4 |
| Completed | Effect of Post-Operative Anesthetics on Post-Operative Pain in Patients Receiving Endodontic Treatment NCT05338671 | University of Washington | Phase 4 |
| Completed | Effectiveness of Premedication on the Success Rate of Inferior Alveolar Nerve Block NCT05097768 | Alfarabi Colleges | N/A |
| Withdrawn | The Effect of Buccal Infiltration Administration of Clonidine on the Success Rate of Inferior Alveolar Nerve B NCT04186299 | University of California, San Francisco | Phase 4 |
| Completed | Comparison of Preoperative Analgesics on the Efficacy of Inferior Alveolar Nerve Block. NCT05488925 | Farjad Zafar | Phase 4 |
| Unknown | Effect of Diclofenac Potassium Versus Prednisolone on Post-endodontic Pain and Pulpal IL-8 Expression NCT04608981 | Cairo University | Phase 4 |
| Completed | Postoperative Pain Intensity After Pulpotomy NCT05424796 | Cumhuriyet University | Phase 4 |
| Recruiting | Effect of Apical Patency and Local Corticosteroid on Pain and Neuropeptides Release in Patients With Symptomat NCT06457828 | Suez Canal University | N/A |
| Completed | Preoperative Acetaminophen- Caffeine- Codeine Combination and Anaesthetic Success in Patients With Acute Pulpi NCT04202406 | Cairo University | N/A |
| Unknown | Efficacy of Preoperative Diclofenac Potassium- Acetaminophen Combination on Anesthetic Success in Patients Wit NCT04593160 | Cairo University | N/A |
| Completed | Postoperative Pain and Healing in Teeth Treated With GentleWave or EndoActivator NCT04552132 | St. Louis University | N/A |
| Completed | Effect of Preoperative Oral Tramadol on Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversibl NCT04961268 | Alfarabi Colleges | N/A |
| Completed | Full Pulpotomy in Mature Teeth With Symptomatic Irreversible Pulpitis as a Routine Treatment in the Primary Ca NCT05199181 | Rubén Domínguez Pérez | N/A |
| Unknown | Pulpotomy in Mature Permanent Molars Using Biodentine Versus MTA NCT03890835 | Cairo University | N/A |
| Unknown | Effect of Cryotherapy on Postoperative Pain NCT03716635 | Cairo University | N/A |
| Completed | Comparison Between M-Pro and ProTaper Next NCT03692039 | Cairo University | N/A |
| Unknown | Anesthetic Efficacy of 2% Mepivacaine Versus 4% Articaine NCT03725579 | Cairo University | Phase 2 / Phase 3 |
| Completed | Efficacy of Block Injection of an Anti Inflammatory Medicine in Patients With Mandibular Dental Pain NCT03410212 | Azad University of Medical Sciences | Phase 2 |
| Completed | The Effect of Central Sensitization on Assessment Capacity of Patients NCT03553641 | Istanbul Medipol University Hospital | — |
| Unknown | Effect Of XP Endo Finisher Versus Ultrasonic Activated Irrigation On Post-operative Pain In Endodontic Treatme NCT03096587 | Cairo University | N/A |
| Completed | Effect of Inferior Alveolar and Gow-Gates Nerve Block Techniques for Symptomatic Mandibular Molars NCT03117491 | Isfahan University of Medical Sciences | Phase 3 |
| Completed | Pretreatment Aceclofenac Effect on Pain and Analgesic Intake After Endodontic Treatment NCT03335007 | Cairo University | Phase 2 / Phase 3 |
| Completed | Anaesthetic Efficacy of 2% Mepivacaine Versus 4% Articaine With Symptomatic Irreversible Pulpitis NCT04822415 | Cairo University | N/A |
| Completed | Occlusal Reduction Effect on Postendodontic Pain NCT04186897 | Cairo University | N/A |
| Completed | Mepivacaine-Tramadol on the Success of Inferior Alveolar Nerve Block in Symptomatic Irreversible Pulpitis NCT02110966 | Daniel Chavarría Bolaños | Phase 4 |
| Completed | Postendodontic Pain on Using Max-i-Probe vs NaviTip as Irrigation Needles NCT04119661 | Cairo University | N/A |