NCT06457828

Effect of Apical Patency and Local Corticosteroid on Pain and Neuropeptides Release in Patients With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Suez Canal University · Academic / Other
• Sex: All
• Age: 21 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The goal of this randomized clinical trial is to learn the effect of using local corticosteroids and maintaining apical patency in reducing post-preparation pain in patients with acute irreversible pulpitis in molar teeth. The main question it aims to answer is: • How effective are using local corticosteroids and maintaining apical patency in reducing post-preparation pain in patients with acute irreversible pulpitis? Participants will be asked to fill a visual analogue scale to record their pain, after receiving a root canal treatment while using local corticosteroids or not as well as maintaining apical patency or not. Researchers will compare the use of corticosteroids and maintaining apical patency in reducing post-operative pain.

Conditions

• Postoperative Pain
• Symptomatic Irreversible Pulpitis

Interventions

Type	Name	Description
PROCEDURE	Non-corticosteroid injection	no infiltration injection of 0.7 ml of dexamethasone lateral to the involved tooth after anesthesia administration.
DRUG	Corticosteroid injection	infiltration injection of 0.7 ml of dexamethasone lateral to the involved tooth after anesthesia administration.

Timeline

• Start date: 2021-02-01
• Primary completion: 2024-06-01
• Completion: 2024-09-01
• First posted: 2024-06-13
• Last updated: 2024-06-13

Locations

1 site across 1 country: Egypt