NCT07112859

Evaluation of Success of Complete Pulpotomy With Biodentine on Mature Permanent Single Rooted Teeth With Symptomatic Irreversible Pulpitis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: HITEC-Institute of Medical Sciences · Academic / Other
• Sex: All
• Age: 20 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

This study aims to evaluate the clinical success of complete pulpotomy using Biodentine in mature permanent single-rooted teeth diagnosed with symptomatic irreversible pulpitis. Complete pulpotomy involves removal of the coronal pulp and preservation of radicular pulp vitality using a biocompatible pulp-capping material. Biodentine, a calcium silicate-based cement, has favorable biological properties, including biocompatibility, antibacterial effects, and dentin bridge formation potential. A total of 84 patients meeting the inclusion criteria will be enrolled and treated by a single operator. Clinical success will be evaluated at 7 days, 1 month, and 3 months based on absence of pain, swelling, tenderness to percussion, and radiographic signs of periapical pathology.

Conditions

• Symptomatic Irreversible Pulpitis

Interventions

Type	Name	Description
PROCEDURE	Complete Pulpotomy with Biodentine	Administration of local anesthesia followed by rubber dam isolation. Removal of coronal pulp tissue to perform a complete pulpotomy. Hemostasis achieved with saline-soaked cotton pellet. Placement of Biodentine as the pulp-capping agent on the radicular pulp. Temporary restoration placed immediately after Biodentine placement. Permanent composite restoration placed after 1 week. Follow-up visits at 7 days, 1 month, and 3 months for clinical and radiographic evaluation.

Timeline

• Start date: 2024-07-02
• Primary completion: 2025-07-02
• Completion: 2025-07-02
• First posted: 2025-08-08
• Last updated: 2025-08-08

Locations

1 site across 1 country: Pakistan