| Recruiting | Ketamine add-on Therapy for Established Status Epilepticus Treatment Trial (KESETT) NCT06907173 | University of Virginia | Phase 3 |
| Not Yet Recruiting | Targeted Hypothermia Versus Targeted Normothermia After Convulsive Refractory Status Epilepticus NCT07383779 | Versailles Hospital | Phase 3 |
| Recruiting | Simulation Trial of Telemedical Support for Paramedics NCT06441760 | Boston Medical Center | N/A |
| Not Yet Recruiting | Lacosamide Intravenous Injection for Emergency Termination of Status Epilepticus NCT06966830 | Second Affiliated Hospital of Guangzhou Medical University | — |
| Completed | Comparison of Intravenous Brivaracetam Versus Levetiracetam in the Management of Status Epilepticus NCT07163572 | Muhammad Aamir Latif | N/A |
| Completed | Efficacy Comparison Between Levetiracetam and Valproic Acid in Pediatric Patients With Status Epilepticus NCT07052136 | RESnTEC, Institute of Research | N/A |
| Recruiting | Patient-reported Outcome and Patient-reported Experience After Status Epilepticus NCT06100978 | Versailles Hospital | — |
| Recruiting | PeRampanel fOr Status ePilEpticus pRophylaxis Post-cardiac Arrest NCT06401707 | University of California, San Francisco | Phase 2 |
| Recruiting | Improving Status Epilepticus Treatment Times NCT06194747 | Nationwide Children's Hospital | N/A |
| Completed | Artificial Intelligence-powered Virtual Assistant for Emergency Triage in Neurology NCT06334796 | Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia | EARLY_Phase 1 |
| Recruiting | The Role of Imaging in the Diagnosis, Management and Prognosis of Possible Non-convulsive Status Epilepticus NCT06017973 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Terminated | Feasibility Study: tDCS for Treatment of Refractory Status Epilepticus NCT05934903 | Yale University | N/A |
| Recruiting | buRst-supprESsion TO Stop Refractory Status Epilepticus Post-cardiac Arrest NCT05851391 | University of California, San Francisco | Phase 2 |
| Completed | Comparison of Narcotrend and Cerebral Function Analysing Monitor in Intensive Care to Monitor Seizures and Dee NCT06067750 | Nottingham University Hospitals NHS Trust | — |
| Enrolling By Invitation | The Efficacy and Safety of Levetiracetam Versus Fosphenytoin in Convulsive Status Epilepticus NCT06403150 | Dhaka Medical College | Phase 4 |
| Withdrawn | Safety and Efficacy Study of IV Ganaxolone as Adjuvant Therapy for Established Status Epilepticus (ESE) NCT05757544 | Marinus Pharmaceuticals | Phase 2 |
| Recruiting | Sustained Effort Network for Treatment of Status Epilepticus/European Academy of Neurology Registry on Refract NCT05839418 | Erasme University Hospital | — |
| Recruiting | Exogenous Ketone Esters for Refractory Status Epileptics NCT05674552 | Sohag University | Phase 2 / Phase 3 |
| Withdrawn | VIGAB-BIOSTAT: Neuronal Injury Panel Substudy NCT05000320 | University of Florida | — |
| Recruiting | The STatus Epilepticus Prognosis Study NCT06590883 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | — |
| Completed | Patient-reported Outcome After Status Epilepticus NCT05491590 | Versailles Hospital | — |
| Unknown | Ketogenic Diet for Status Epilepticus in Children Post Cessation of Convulsive Status Epilepticus NCT05591508 | All India Institute of Medical Sciences | N/A |
| Completed | Point-of-care EEG in the Pediatric Emergency Department NCT05418634 | University Children's Hospital, Zurich | — |
| Completed | Efficacy of Phenytoin vs Levetiracetam in Status Epilepticus at Institute of Child Health,Faisalabad NCT06067412 | Shaheed Zulfiqar Ali Bhutto Medical University | N/A |
| Unknown | Assessment of Adults Epidemiological Characteristics of Status Epilepticus in the French West Indies and in Fr NCT05246566 | University Hospital Center of Martinique | — |
| Recruiting | Dual Anti-glutamate Therapy in Super-refractory Status Epilepticus After Cardiac Arrest NCT05756621 | University of Milano Bicocca | — |
| Recruiting | Rapid-Response EEG in Children With Suspected Status Epilepticus NCT06564662 | Children's Hospital at Montefiore | — |
| Recruiting | De-identified UNMH EEG Corpus Database Creation With Fully De-identified Clinical Information NCT05140265 | University of New Mexico | — |
| Recruiting | Augmented Renal Clearance in Neurocritical Care NCT07410624 | University of Alberta | — |
| Completed | eegCap Application in Paediatrics wiTh redUced GCS in REsus NCT05259891 | University College Cork | — |
| Completed | Effectiveness of Combined Levetiracetam and Midazolam in Generalized Convulsive Status Epilepticus in Children NCT04926844 | Sohag University | Phase 2 |
| Completed | Study of Midazolam in Healthy Adults NCT04679623 | Rafa Laboratories | Phase 1 |
| Withdrawn | Tracheostomy With Bedside Simultaneous Gastrostomy Vs Usual Care Tracheostomy And Delayed Gastrostomy Placemen NCT04758052 | University of Mississippi Medical Center | N/A |
| Completed | The Etiology of New-onset Status Epilepticus NCT05647525 | Jie Liu | — |
| Completed | Randomized Therapy In Status Epilepticus NCT04391569 | Marinus Pharmaceuticals | Phase 3 |
| Completed | Improving Emergency Management of Status Epilepticus NCT03883516 | University Hospital, Basel, Switzerland | N/A |
| Recruiting | Study of Pathophysiology of Status Epilepticus and Dysimmune Encephalitis NCT04421846 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Refractory Status Epilepticus Treatment: Quality and Efficacy of Coma Induction NCT04333082 | University Hospital, Basel, Switzerland | — |
| Completed | COVID-19 Brain Injury NCT04496076 | University of Pittsburgh | — |
| Recruiting | EEG Monitoring for Refractory Status Epilepticus NCT04170491 | Barts & The London NHS Trust | N/A |
| Completed | LORA-PITA IV General Investigation NCT03905798 | Pfizer | — |
| Unknown | Comparison of Efficacy of Phenytoin With Levetireacetam for the Management of Children With Status Epilepticus NCT04829838 | ayesha tariq | Phase 4 |
| Terminated | SURESTEP: Transcranial Direct Current Stimulation in Super Refractory Status Epilepticus NCT03819543 | University of Manitoba | N/A |
| Completed | Pilot Simulation RCT of Telemedical Support for Paramedics NCT03742167 | Boston Medical Center | N/A |
| Unknown | Diagnostic Value of Prehospital EEG in Non-convulsive Status Epilepticus NCT02344706 | Helsinki University Central Hospital | — |
| Completed | Seizure Rescue Medication: Caregiver Education in a Simulation Setting NCT03562351 | Boston Children's Hospital | N/A |
| Recruiting | Status Epilepticus in the Critically Ill Patients NCT03457831 | Ictal Group | — |
| Completed | Intravenous Ganaxolone as Adjunctive Therapy to Treat Subjects With Status Epilepticus NCT03350035 | Marinus Pharmaceuticals | Phase 2 |
| Unknown | Mainz Epilepsy Registry NCT05267405 | Johannes Gutenberg University Mainz | — |
| Unknown | Management of Non Convulsive Status Epilepticus NCT03245099 | Assiut University | — |
| Completed | Smartphone Apps for Pediatric Resuscitation NCT02958605 | St. Justine's Hospital | N/A |
| Unknown | A Clinical Study of Children With Status Epilepticus in China NCT03378687 | Fudan University | — |
| Terminated | Repeated TMS at Low Frequencies to Reduce Seizure Occurrence NCT03154307 | Baptist Health South Florida | N/A |
| Completed | Creation, Implementation, and Analysis of a Seizure Action Plan NCT02995759 | Boston Children's Hospital | — |
| Terminated | Ketamine in Refractory Convulsive Status Epilepticus NCT02431663 | Meyer Children's Hospital IRCCS | Phase 3 |
| Terminated | Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Epilepsy NCT02560597 | University Hospital, Ghent | N/A |
| Completed | EEG in In-hospital Patients With Seizure or Altered Mental State NCT02383745 | Kuopio University Hospital | — |
| Completed | Lorazepam for the Treatment of Status Epilepticus or Repetitive Status Epilepticus in Japan NCT02239380 | Pfizer | Phase 3 |
| Recruiting | Improving Outcomes for Patients With Life-Threatening Neurologic Illness NCT04189471 | University of Maryland, Baltimore | — |
| Completed | TELSTAR: Treatment of ELectroencephalographic STatus Epilepticus After Cardiopulmonary Resuscitation NCT02056236 | University of Twente | N/A |
| Withdrawn | Levetiracetam, Lacosamide and Ketamine as Adjunctive Treatment of Refractory Status Epilepticus NCT02726867 | Mid-Atlantic Epilepsy and Sleep Center, LLC | Phase 3 |
| Completed | Comparison Between Lorazepam, Clonazepam and Clonazepam + Fosphenytoin for the Treatment of Out-of-hospital Ge NCT01870024 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Completed | Stiripentol for the Treatment of Refractory Status Epilepticus NCT06540378 | University Hospital Marburg | — |
| Completed | Ketogenic Diet for Refractory Status Epilepticus NCT01796574 | Johns Hopkins University | N/A |
| Completed | Prevalence of Acute Critical Neurological Disease in Children: a Global Epidemiological Assessment NCT02381977 | University of Pittsburgh | — |
| Completed | Putting Electroencephalography (EEG) in the Emergency Department NCT01355211 | Bio-Signal Group Corp. | — |
| Unknown | Safety and Efficacy of Intravenous Valproate in Pediatric Status Epilepticus and Acute Repetitive Seizures NCT01268904 | Hillel Yaffe Medical Center | — |
| Completed | Status Epilepticus in Men and Women: Clinical Presentation, Management, and Outcomes NCT07443241 | University Hospital Marburg | — |
| Completed | Paramedic Treatment of Prolonged Seizures by Intramuscular Versus Intravenous Anticonvulsant Medications NCT00809146 | Robert Silbergleit | Phase 3 |
| Completed | Nasal Versus Venous Lorazepam for Control of Acute Seizures in Children NCT00735527 | All India Institute of Medical Sciences | Phase 3 |
| Completed | Efficacy and Safety Study Comparing Lorazepam and Diazepam for Children in the Emergency Department With Seizu NCT00621478 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Phase 2 / Phase 3 |
| Unknown | Safety and Tolerability Study of Levetiracetam to Treat Patients With Status Epilepticus NCT00362141 | Medical Center Haaglanden | Phase 2 |
| Terminated | Randomized Trial Comparing 3 Routes of Delivering Lorazepam to Children. NCT00343096 | Kamuzu University of Health Sciences | Phase 3 |
| Terminated | Treatment of Refractory Status Epilepticus NCT00265616 | Brigham and Women's Hospital | Phase 3 |
| Completed | Prognosis Factors Associated With Convulsive Status Epilepticus in Adults NCT00318578 | Versailles Hospital | — |
| Completed | Lorazepam for the Treatment of Status Epilepticus in Children NCT00114569 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Phase 1 |
| Completed | Intranasal Lorazepam Versus Intramuscular Paraldehyde in Paediatric Convulsions NCT00116064 | Kamuzu University of Health Sciences | Phase 3 |
| Completed | Phase III Randomized Study of Diazepam Vs Lorazepam Vs Placebo for Prehospital Treatment of Status Epilepticus NCT00004297 | National Institute of Neurological Disorders and Stroke (NINDS) | Phase 3 |