| Not Yet Recruiting | Assessment of the Long-term Efficacy of Moderately Hypofractionated Neoadjuvant Radiotherapy Soft Tissue Sarco NCT07507773 | Centre Oscar Lambret | Phase 2 |
| Recruiting | Hypofractionated, 3-week, Preoperative Proton or X-ray Radiotherapy for Patients With Localized Soft Tissue Sa NCT07169344 | Oslo University Hospital | Phase 2 |
| Recruiting | Dose-escalated, Hypofractionated, Definitive Proton Radiotherapy for Patients With Inoperable Soft Tissue Sarc NCT07173972 | Oslo University Hospital | Phase 2 |
| Recruiting | A Phase 0 Multicenter Study of the Pharmacodynamic Effects of Intratumoral Microdose Administration of PBA-011 NCT06700070 | Pure Biologics S.A. | EARLY_Phase 1 |
| Withdrawn | Fluorescent Aided Resection and Evaluation of Soft Tissue Sarcomas (FLARES) NCT06252727 | University of California, Davis | Phase 1 |
| Completed | A Study of the Intratumoral Microdose Administration of PBA-0405 in Patients With Solid Tumors NCT06273852 | Pure Biologics S.A. | EARLY_Phase 1 |
| Unknown | A Study of Surufatinib in the Treatment of Advanced Soft Tissue Sarcoma NCT06110650 | Fudan University | N/A |
| Terminated | Sarcomas and DDR-Inhibition; a Combined Modality Study NCT05116254 | The Netherlands Cancer Institute | Phase 1 |
| Recruiting | Combination of Pembrolizumab and Cabozantinib in Patients With Advanced Sarcomas NCT05182164 | Institut Bergonié | Phase 2 |
| Active Not Recruiting | Phase 1 Study of SON-1010 in Adult Patients With Advanced Solid Tumors NCT05352750 | Sonnet BioTherapeutics | Phase 1 |
| Recruiting | Precision Medicine Approaches for Neoadjuvant Therapy in High-risk Sarcoma Patients NCT07432932 | Royal Marsden NHS Foundation Trust | — |
| Recruiting | Propranolol and Pembrolizumab in Advanced Soft Tissue Sarcoma Patients NCT05961761 | Niels Junker | Phase 2 |
| Recruiting | Blood and Tissue Extraction for Immunological Examinations During Neoadjuvant Therapy of Soft Tissue Sarcomas NCT06385288 | University Hospital Tuebingen | N/A |
| Recruiting | Retifanlimab (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue Sarcoma NCT04577014 | Memorial Sloan Kettering Cancer Center | Phase 1 / Phase 2 |
| Active Not Recruiting | Pre-operative RadiothErapy for Soft Tissue SarcOmas NCT04617327 | McGill University Health Centre/Research Institute of the McGill University Health Centre | N/A |
| Active Not Recruiting | Combination of Nivolumab Plus Relatlimab in Patients With Advanced or Metastatic Soft-tissue Sarcoma: a Proof- NCT04095208 | Institut Bergonié | Phase 2 |
| Recruiting | Combined Treatment of Patients With Soft Tissue Sarcoma Including Preoperative Stereotactic Radiation Therapy NCT04330456 | N.N. Petrov National Medical Research Center of Oncology | N/A |
| Completed | Prospective Identification of Predictive Biomarkers of Trabectedin Efficacy in Non-L Soft-tissue Sarcoma Patie NCT04008238 | Institut Bergonié | N/A |
| Completed | Efficacy and Safety of Anlotinib in Adjuvant Therapy for High-grade Soft Tissue Sarcoma NCT03951571 | Fudan University | Phase 2 |
| Completed | Study of a Cohort of Cases of Synovial Sarcoma Treated in the Orthopedic Surgery and Traumatology Department o NCT03833037 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | — |
| Terminated | Quality of Life in Patients With Non-adipocyte Soft Tissue Sarcoma Under Palliative Chemotherapy or Pazopanib NCT03735758 | GWT-TUD GmbH | Phase 4 |
| Terminated | Low Dose Continuous Cyclophosphamide vs Standard Doxorubicin in Advanced Sarcoma Elderly Patients NCT04656262 | Istituto Oncologico Veneto IRCCS | Phase 3 |
| Completed | Lenvatinib and Eribulin in Advanced Soft Tissue Sarcoma NCT03526679 | National Taiwan University Hospital | Phase 1 / Phase 2 |
| Active Not Recruiting | Impact of Locoregional Treatment of Soft Tissue Sarcoma on Status of Patients Aged 70 Years and Over NCT03077178 | Institut Bergonié | N/A |
| Completed | Safety, Tolerability, and Efficacy of Doxorubicin and Pembrolizumab for Sarcoma NCT03056001 | Wake Forest University Health Sciences | Phase 2 |
| Withdrawn | Apatinib for Advanced Soft Tissue Sarcoma Patients: a Phase 2, Multicenter Trial NCT03104335 | Peking University People's Hospital | Phase 2 |
| Unknown | Radiation Effects on Bone NCT03134742 | State University of New York - Upstate Medical University | — |
| Completed | Precise Local Injection of Anti-cancer Drugs Using Presage's CIVO Device in Soft Tissue Sarcoma NCT03056599 | Presage Biosciences | Phase 1 |
| Completed | A Study of IMRT in Primary Bone and Soft Tissue Sarcoma NCT02520128 | University College, London | N/A |