| Completed | Diagnostic Accuracy of The Water Immersion Wrinkle Test for Small Fiber Neuropathy NCT07255573 | HOSPITAL BRITANICO DE BUENOS AIRES | — |
| Not Yet Recruiting | IVIG in Painful Sensory Neuropathy NCT06183008 | Sorlandet Hospital HF | Phase 4 |
| Withdrawn | Analysis of Cutaneous Nerve Biopsies in Gastrointestinal Motility Disorders NCT04872452 | Johns Hopkins University | N/A |
| Recruiting | IVIG in the Treatment of Autoimmune Small Fiber Neuropathy With TS-HDS, FGFR-3, or Plexin D1 Antibodies NCT04153422 | Endeavor Health | Phase 2 |
| Completed | Comparison of Histamine and Local Heating for Evoking the Axon-reflex Flare Response in Diabetes NCT05921097 | Aalborg University Hospital | — |
| Unknown | Chronic Pain Rehabilitation in Patients With Small Fiber Neuropathy NCT05798949 | Academisch Ziekenhuis Maastricht | N/A |
| Completed | Diabetic Small Fiber Neuropathy: Clinical, Electrophysiological and Neurosonographic Study NCT05993871 | Tanta University | — |
| Completed | Diabetes, Falls, and Fractures NCT05389566 | Aalborg University Hospital | — |
| Completed | Reference Values of Intraepidermal Nerve Fiber Density in Children and Small Fiber Neuropathy in Neurodevelopm NCT05645874 | Heinrich-Heine University, Duesseldorf | — |
| Recruiting | Detection of Small Fiber Neuropathy Using Skin Properties NCT04759443 | Brigham and Women's Hospital | — |
| Unknown | Small Fiber Assessment by Cutaneous Silent Period NCT04863820 | Cairo University | — |
| Completed | Cutaneous Silent Period Assessment in Primary Sjögren's Syndrome NCT05380804 | Marmara University | — |
| Unknown | Biometric and Biological Data for Diagnosis and Therapy of Pain Patients NCT04835779 | RWTH Aachen University | — |
| Suspended | Establishing Normative Values for Thermal Detection and Pain Threshold Established by the Psi Method NCT04611048 | Université Catholique de Louvain | N/A |
| Completed | Evaluation of Nicotinamide Riboside in Prevention of Small Fiber Axon Degeneration and Promotion of Nerve Rege NCT03912220 | Johns Hopkins University | Phase 2 |
| Unknown | Causes Associated With Small Fiber Neuropathy (SFN). NCT04170205 | University Hospital, Brest | — |
| Recruiting | Autonomic Small Fiber Neuropathy and Ehlers Danlos Syndromes - Prospective Study and Registry NCT04310644 | RWTH Aachen University | — |
| Recruiting | Medico-economic and Quality of Life Impact of Sjogren-associated Small Fiber Neuropathy NCT03509064 | Assistance Publique - Hôpitaux de Paris | — |
| Unknown | fMRI-study in Patients With Small Fiber Neuropathy NCT03889080 | Academisch Ziekenhuis Maastricht | — |
| Completed | IVIg for Small Fiber Neuropathy With Autoantibodies TS-HDS and FGFR3 NCT03401073 | Beth Israel Deaconess Medical Center | Phase 2 |
| Terminated | Spinal Cord Stimulation in Small Fibre Neuropathy NCT02905396 | Academisch Ziekenhuis Maastricht | N/A |
| Terminated | Efficacy and Safety Study of BIIB074 in Participants With Small Fiber Neuropathy NCT03339336 | Biogen | Phase 2 |
| Completed | Titration Study of ABX-1431 NCT03447756 | Abide Therapeutics | Phase 1 |
| Completed | A Study to Evaluate the Efficacy and Safety of VX-150 in Treating Subjects With Pain Caused by Small Fiber Neu NCT03304522 | Vertex Pharmaceuticals Incorporated | Phase 2 |
| Completed | Assessment of Small Fiber Neuropathy in Rare Diseases Using Sudoscan NCT02985710 | Massachusetts General Hospital | N/A |
| Completed | Intravenous Immunoglobulin Therapy for Small Fiber Neuropathy NCT02637700 | Academisch Ziekenhuis Maastricht | Phase 2 |
| Unknown | Skin Biopsy in the Diagnosis of Small Fiber Neuropathy in Chinese Patients With Diabetes NCT04071535 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | — |
| Completed | Autofluorescent Flavoprotein Imaging of Intraepidermal Nerve Fibers: a Pilot Study NCT02537951 | Erasmus Medical Center | N/A |
| Completed | Safety and Tolerability of Lacosamide in Patients With Gain-of-function Nav1.7 Mutations Related Small Fiber N NCT01911975 | Academisch Ziekenhuis Maastricht | Phase 3 |
| Unknown | Small-fiber Neuropathy in Chronic Kidney Disease NCT01078857 | National Taiwan University Hospital | N/A |
| Terminated | Evaluation of Pregabalin in Idiopathic Small Fiber Neuropathy NCT00787462 | University of Alberta | N/A |