SMA

17 registered clinical trials studyying SMA — 5 currently recruiting.

Status	Trial	Sponsor	Phase
Recruiting	A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular A NCT07047144	Scholar Rock, Inc.	Phase 2
Recruiting	Study of the Reproducibility of the French Version of the Modified SMAFRS Scale NCT07321990	Institut de Myologie, France	—
Active Not Recruiting	Spinal Cord Stimulation for the Treatment of Motor Deficits in People With Spinal Muscular Atrophy - Upper Lim NCT06300996	Marco Capogrosso	N/A
Recruiting	A Head-to-head Study Comparing the Functional Value of Two Models of Robotically Assisted Rehabilitation in SM NCT06322654	Wiktor Dega University Orthopedic and Rehabilitation Hospital	N/A
Active Not Recruiting	Long-Term Safety & Efficacy of Apitegromab in Patients With SMA Who Completed Previous Trials of Apitegromab NCT05626855	Scholar Rock, Inc.	Phase 3
Active Not Recruiting	A Study to Evaluate the Efficacy and Safety of Taldefgrobep Alfa in Participants With Spinal Muscular Atrophy NCT05337553	Biohaven Pharmaceuticals, Inc.	Phase 3
Completed	Efficacy and Safety of Apitegromab in Patients With Later-Onset Spinal Muscular Atrophy Treated With Nusinerse NCT05156320	Scholar Rock, Inc.	Phase 3
Active Not Recruiting	Long-term Follow-up Study of Patients Receiving Onasemnogene Abeparvovec-xioi NCT04042025	Novartis Gene Therapies	Phase 3
Completed	An Active Treatment Study of SRK-015 in Patients With Type 2 or Type 3 Spinal Muscular Atrophy NCT03921528	Scholar Rock, Inc.	Phase 2
Completed	Single-Dose Gene Replacement Therapy Clinical Trial for Participants With Spinal Muscular Atrophy Type 1 NCT03461289	Novartis Gene Therapies	Phase 3
Recruiting	Swiss Registry for Neuromuscular Disorders NCT05102916	University of Bern	—
Unknown	Hyperkinetic Movements in Patients With Disease of Motor Neurons and Their Response to Treatment With Nusiners NCT04825119	University Medical Centre Ljubljana	—
Completed	SPACE Trial: Pyridostigmine vs Placebo in SMA Types 2, 3 and 4 NCT02941328	UMC Utrecht	Phase 2
Completed	Differential Study of Muscle Transcriptome NCT01984957	Assistance Publique - Hôpitaux de Paris	N/A
Recruiting	UK SMA Patient Registry NCT04292574	Newcastle University	—
Completed	Study to Evaluate the Efficacy of Riluzole in Children and Young Adults With Spinal Muscular Atrophy (SMA) NCT00774423	Assistance Publique - Hôpitaux de Paris	Phase 2 / Phase 3
Available	EAP of Apitegromab for Patients With Spinal Muscular Atrophy NCT06877689	Scholar Rock, Inc.	—