| Unknown | A Clinical Evaluation of the Safety and Efficacy of Randomized Placebo Versus the 8-aminoquinoline Tafenoquine NCT05947812 | 60P Australia Pty Ltd | Phase 2 |
| Active Not Recruiting | A Study to Learn About Variant-Adapted COVID-19 RNA Vaccine Candidate(s) in Healthy Children NCT05543616 | BioNTech SE | Phase 3 |
| Completed | A Clinical Trial of COVAC-2 in Adults NCT05209009 | University of Saskatchewan | Phase 2 |
| Unknown | NA-831, Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection NCT04452565 | Biomed Industries, Inc. | Phase 2 / Phase 3 |
| Withdrawn | A Clinical Trial of COVAC-1, a COVID-19 Vaccine, in Generally Healthy Adults NCT05155982 | University of Saskatchewan | Phase 1 |
| Withdrawn | COVIDNOCHE Trial (HFNO Versus CPAP Helmet) in COVID-19 Pneumonia NCT04381923 | University of Pennsylvania | N/A |
| Unknown | Early Treatment of Vulnerable Individuals With Non-Severe SARS-CoV-2 Infection NCT04920838 | ANRS, Emerging Infectious Diseases | Phase 2 / Phase 3 |
| Terminated | Antiseptic Mouthwash / Pre-Procedural Rinse on SARS-CoV-2 Load (COVID-19) NCT04409873 | University of California, San Francisco | Phase 2 |
| Completed | Communication in ICU During COVID-19 NCT04602351 | NMC Specialty Hospital | — |
| Terminated | Isavuconazole for the Prevention of COVID-19-associated Pulmonary Aspergillosis NCT04707703 | Jeffrey Jenks, MD, MPH | Phase 3 |
| Completed | A Clinical Trial of COVAC-2 in Healthy Adults NCT04702178 | University of Saskatchewan | Phase 1 |
| Withdrawn | Metformin Glycinate in Patients With MS or DM2 , Hospitalized With COVID-19 and SARS Secondary to SARS-CoV-2 NCT04626089 | Laboratorios Silanes S.A. de C.V. | Phase 2 |
| Suspended | Fluvoxamine for Adults With Mild to Moderate COVID-19 NCT04711863 | Asan Medical Center | Phase 2 |
| Completed | Study to Assess Efficacy and Safety of Inhaled Interferon-β Therapy for COVID-19 NCT04732949 | Synairgen Research Ltd. | Phase 3 |
| Completed | Combination Therapies to Reduce Carriage of SARS-Cov-2 and Improve Outcome of COVID-19 in Ivory Coast: a Phase NCT04466241 | ANRS, Emerging Infectious Diseases | Phase 2 / Phase 3 |
| Unknown | CORONA (COvid pRONe hypoxemiA): Prone Positioning for Hypoxemic COVID-19 Patients With Do-not-intubate Goals NCT04402879 | University of Calgary | N/A |
| Terminated | Efficacy and Safety of Dipeptidyl Peptidase-4 Inhibitors in Diabetic Patients With Established COVID-19 NCT04371978 | Rabin Medical Center | Phase 3 |
| Unknown | Therapeutic Use of Convalescent Plasma in the Treatment of Patients With Moderate to Severe COVID-19 NCT04516811 | South African National Blood Service | Phase 3 |
| Completed | Treatment of SARS Caused by COVID-19 With Ruxolitinib NCT04334044 | Grupo Cooperativo de Hemopatías Malignas | Phase 1 / Phase 2 |
| Unknown | Daily Regimen of Tenofovir/Emtricitabine as Prevention for COVID-19 in Health Care Personnel in Colombia NCT04519125 | Hospital Universitario San Ignacio | Phase 2 / Phase 3 |
| Completed | An Exploratory Study of ADR-001 in Patients with Severe Pneumonia Caused by SARS-CoV-2 Infection NCT04522986 | Rohto Pharmaceutical Co., Ltd. | Phase 1 |
| Terminated | Ruxolitinib for Acute Respiratory Disorder Syndrome Due to COVID-19 NCT04477993 | Vanderson Geraldo Rocha | Phase 2 / Phase 3 |
| Unknown | Tocilizumab in Coronavirus-19 Positive Patients NCT04423042 | University of Calgary | Phase 3 |
| Completed | Metformin Glycinate, Treatment of Patients With COVID-19 and Severe Acute Respiratory Syndrome Secondary to SA NCT04625985 | Laboratorios Silanes S.A. de C.V. | Phase 2 |
| Completed | Vagus Nerve Stimulation ARDS Prevention Trial for COVID-19 Hospitalized Patients NCT04379037 | Nemechek Technologies | N/A |
| Completed | A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Orally Inhaled Aerosolized Hydroxychloroq NCT04461353 | Pulmoquine Therapeutics, Inc | Phase 1 |
| Completed | COVID-19 Related Health and Infection Control Practices Among Dentists NCT04423770 | American Dental Association | — |
| Completed | A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19 NCT04402060 | Apellis Pharmaceuticals, Inc. | Phase 1 / Phase 2 |
| Unknown | Natural Killer Cell (CYNK-001) Infusions in Adults With COVID-19 NCT04365101 | Celularity Incorporated | Phase 1 / Phase 2 |
| Completed | Antibody Seroprevalence and Rate of Asymptomatic Infections With SARS-CoV-2 in Austrian Hospital Personnel. NCT04354779 | AUVA | — |
| Unknown | Surgery and Lung Ultrasound in COVID-19 Infection NCT04661631 | Fundacion Clinica Valle del Lili | — |
| Completed | Host-pathogen Interactions During SARS-CoV-2 Infection NCT04376476 | Hospices Civils de Lyon | N/A |
| Completed | Efficacy and Safety of Early COVID-19 Convalescent Plasma in Patients Admitted for COVID-19 Infection NCT04375098 | Pontificia Universidad Catolica de Chile | Phase 2 |
| Unknown | African Covid-19 Critical Care Outcomes Study NCT04367207 | University of Cape Town | — |
| Completed | ScreenNC, a Study to Determine the Number of Asymptomatic Individuals Who Have Antibodies to the Virus That Ca NCT04367740 | University of North Carolina, Chapel Hill | — |
| Unknown | Monocytes and NK Cells Activity in Covid-19 Patients NCT04375176 | Università degli Studi dell'Insubria | — |
| Completed | Prone Positioning and Regional Ventilation in Mechanically Ventilated COVID-19 Patients NCT04359407 | Walid HABRE | — |
| Unknown | Ruxolitinib for the Treatment of Acute Respiratory Distress Syndrome in Patients With COVID-19 Infection NCT04361903 | Azienda USL Toscana Nord Ovest | — |
| Completed | Risk Stratification With Chest CT to Rule-out Suspected SARS-CoV-2 Infections NCT04357938 | Jena University Hospital | — |
| Completed | Beaumont Health Large-scale Automated Serologic Testing for COVID-19 NCT04349202 | Corewell Health East | — |
| Completed | Pro-thrombotic Status in Patients with SARS-Cov-2 Infection NCT04343053 | University Hospital of Ferrara | N/A |
| Completed | Cell Therapy Using Umbilical Cord-derived Mesenchymal Stromal Cells in SARS-CoV-2-related ARDS NCT04333368 | Assistance Publique - Hôpitaux de Paris | Phase 1 / Phase 2 |
| Active Not Recruiting | Pulmonary Fibrosis During Severe COVID-19 Pneumonia NCT04987528 | Hôpital Européen Marseille | — |
| Completed | Evaluation of Sedation in COVID-19 ARDS NCT04667936 | Goethe University | — |
| No Longer Available | Treatment Of CORONAVIRUS DISEASE 2019 (COVID-19) With Anti-Sars-CoV-2 Convalescent Plasma (ASCoV2CP) NCT04360486 | U.S. Army Medical Research and Development Command | — |