| Not Yet Recruiting | Estradiol Supplementation and Rotator Cuff Repair NCT06318403 | University of Utah | Phase 2 |
| Suspended | Tapestry Rotator Cuff Repair PMCF NCT06287853 | Zimmer Biomet | — |
| Not Yet Recruiting | Contextually Enriched Individualized Exercise Versus Contextually Fixed Exercise for Rotator Cuff-Related Shou NCT07428070 | Istanbul Nisantasi University | N/A |
| Not Yet Recruiting | Mulligan's Mobilization in Rotator Cuff Pathology NCT07525297 | Yuzuncu Yil University | N/A |
| Recruiting | Clinical Outcomes of Arthroscopic Surgeries for Shoulder and Knee Sports Injuries NCT07501013 | Second Affiliated Hospital, School of Medicine, Zhejiang University | — |
| Not Yet Recruiting | Telerehabilitation for Shoulder Surgery Recovery NCT07392502 | NYU Langone Health | N/A |
| Not Yet Recruiting | Effect of a Posterior Shoulder Pillow on Pain and Sleep Quality After Rotator Cuff Repair NCT07372222 | Peking University Third Hospital | N/A |
| Not Yet Recruiting | Post-Market Clinical Follow-up (PMCF) Study of the Pitch-Patch for the Augmentation or Reinforcement of the Ro NCT05906004 | Xiros Ltd | — |
| Active Not Recruiting | Mulligan and Proprioceptive Neuromuscular Facilitation Techniques in Individuals With Rotator Cuff Lesions NCT07294729 | Medipol University | N/A |
| Recruiting | Postoperative Rotator Cuff Rehabilitation: Functional, Pain and Sleep Quality NCT07135375 | LAURA CASTILLO VEJAR | N/A |
| Not Yet Recruiting | The Relationship Pain Beliefs With Kinesiophobia, Catastrophizing, Pain Knowledge, and Shoulder Functional Dis NCT07118163 | Istanbul University - Cerrahpasa | — |
| Recruiting | Safety and Efficacy of Platelet-Rich Plasma Combined With Compound Betamethasone in Arthroscopic Surgery for R NCT07348016 | Second Affiliated Hospital of Nanchang University | N/A |
| Withdrawn | French Cohort of Patients With Rotator Cuff Lesions NCT06371872 | GCS Ramsay Santé pour l'Enseignement et la Recherche | — |
| Completed | Feasibility of an Analgesic Device Enabling Local Anesthetic Delivery and Neuromodulation After Shoulder/Foot NCT06818708 | University of California, San Diego | N/A |
| Recruiting | The Role of Pectoralis Minor Tightness in the Development of Rotator Cuff Tears NCT07228936 | Gazi University | — |
| Not Yet Recruiting | Analysis of Sleep & Recovery Following Rotator Cuff Repair Surgery NCT06625723 | New York Presbyterian Hospital | N/A |
| Recruiting | Investigation of the Effects of Kettlebell Training NCT07289893 | Hacettepe University | N/A |
| Recruiting | Effectiveness of Telerehabilitation as an Alternative to Outpatient Physiotherapy in the 1 Month After Arthros NCT06744218 | Istituto Ortopedico Rizzoli | N/A |
| Enrolling By Invitation | Clinical Outcomes Related to Arthroscopic Rotator Cuff Repair Recovery Using Incrediwear NCT06669741 | Texas Bone and Joint | N/A |
| Completed | Turkish Validity and Reliability of Baltimore Orthopedic Subscapularis Score NCT06635395 | Istanbul Medeniyet University | — |
| Completed | Turkish Validity and Reliability of Short-Western Ontario Rotator Cuff Disability Index NCT06630039 | Istanbul Medeniyet University | — |
| Not Yet Recruiting | Ability of Rotator Cuff Muscle Strength Levels, Assessed by Isokinetic Dynamometry, to Predict Return to Sport NCT06602713 | Ramsay Générale de Santé | N/A |
| Completed | Graded Motor Imagery and Biofeedback in Rotator Cuff Injury NCT06599567 | Istanbul University - Cerrahpasa | N/A |
| Recruiting | From Rotator Cuff Repair to Reverse Shoulder Arthroplasty - Clinical and Radiological Results NCT06644729 | Lovisenberg Diakonale Hospital | — |
| Enrolling By Invitation | Stem Cell Treatment for Regeneration of the Rotator Cuff (Lipo-Cuff Study) NCT06505135 | University of Southern Denmark | Phase 1 |
| Not Yet Recruiting | "Evidence of the Use of Virtual Reality Versus Manual Therapy and Therapeutic Exercise in Rotator Cuff Injury" NCT06482255 | University of Alcala | N/A |
| Recruiting | Utility of Intermittent Cryo-Compression Versus Traditional Icing Following Arthroscopic Rotator Cuff Repair NCT05095909 | Allina Health System | N/A |
| Completed | Bridge Device for Surgical Pain for Rotator Cuff Surgery NCT06071884 | Steven Orebaugh | N/A |
| Not Yet Recruiting | MIRROR Project 44 - Rotator Cuff Repairs With or Without BioEnthesis™ Augmentation NCT06289686 | Brooke Army Medical Center | Phase 4 |
| Recruiting | CBD for Pain Following Orthopedic Shoulder Surgery NCT06381791 | The Methodist Hospital Research Institute | Phase 1 / Phase 2 |
| Suspended | Effectiveness of TheRApeutic ExercIse aNd EDucation on Patients With Massive Rotator Cuff Tears NCT05909930 | Hospital Universitario Fundación Alcorcón | N/A |
| Suspended | Predicting ROtator Cuff Tears Outcomes After Physical Therapy Treatment NCT05913050 | Hospital Universitario Fundación Alcorcón | N/A |
| Completed | Efficacy of Adding Early Scapular Muscles Strengthening Exercise After Rotator Cuff Repair on Scapula Kinemati NCT06851650 | Cairo University | N/A |
| Unknown | Clinical Study On Extracorporeal Shock Wave Therapy For Rotator Cuff Injuries NCT06329154 | Yong Liu, MD | N/A |
| Completed | Manual Therapy Combined With Breathing NCT07180225 | Istanbul Medipol University Hospital | N/A |
| Active Not Recruiting | Shoulder RFA Pilot Study NCT06039345 | University of Utah | — |
| Unknown | Effect of Virtual Reality on Upper Extremity Function Post-operative Rotator Cuff Repair NCT06246305 | Cairo University | N/A |
| Completed | Investigation of the Efficacy of Telerehabilitation in Patients With Rotator Cuff Tendinopathy NCT06024551 | Izmir Democracy University | N/A |
| Terminated | Onlay Versus Inlay Humeral Component in Reverse Total Shoulder Arthroplasty NCT05297305 | Corewell Health East | N/A |
| Completed | Rotator Cuff Integrity and Clinical Outcomes 5 Years After Repair. NCT05988541 | Tartu University Hospital | N/A |
| Completed | Platelet-Rich Plasma Versus Home-Based Exercise for Partial-Thickness Supraspinatus Tears NCT07246434 | Universidad de Extremadura | N/A |
| Unknown | Validity And Reliability Study Of The Turkish Version Of Short Western Ontario Rotator Cuff Index NCT06112444 | Gazi University | — |
| Unknown | Rotator Cuff Tear Severity and Scapular and Rotator Cuff Muscle Activation Patterns NCT05946343 | Ahram Canadian University | — |
| Unknown | Pre-surgical Information Session for People Who Must Undergo Shoulder Rotator Cuff Surgery NCT05886296 | Consorci Sanitari de Terrassa | N/A |
| Completed | ESP vs STB for Pain and Diaphragm Function for Shoulder Surgery NCT05822414 | National Taiwan University Hospital | N/A |
| Unknown | Effectiveness of Non-surgical Management in Rotator Cuff Calcific Tendinopathy (THE EFFECT TRIAL) NCT05478902 | University of Valencia | N/A |
| Completed | The Effect of Core Stability Exercises on Pain, Muscle Strength, and Muscle Architecture in Tennis Players Wit NCT06402162 | Ankara University | N/A |
| Completed | Does Physical Activity Provide Additional Benefit In Patients With Rotator Cuff Related Shoulder Pain? NCT05821283 | Istanbul University | N/A |
| Recruiting | The Western Ontario Rotator Cuff Index Arabic Version NCT05300607 | Cairo University | — |
| Completed | US-Guided Preemptive Brachial Plexus Blockade May Reduce Post-operative Pain: a Randomized Study NCT04005534 | University of Sao Paulo General Hospital | N/A |
| Completed | Online Education to Improve the Management of Rotator Cuff Related Shoulder Pain NCT04952623 | Marmara University | N/A |
| Recruiting | Subscap Reverse Shoulder Arthroplasty NCT05344898 | University of Maryland, Baltimore | N/A |
| Completed | The Effects of Myofascial Release Technique NCT06070493 | Gazi University | N/A |
| Recruiting | Use of the REGENETEN™ Bioinductive Implant System in High Grade Partial-thickness Tears NCT05444465 | Smith & Nephew, Inc. | N/A |
| Withdrawn | Use of Nanoscaffold Augmentation in Rotator Cuff Repair: Clinical Outcome and Ultrasound Assessment of Healing NCT04361266 | Joshua Szabo, MD | N/A |
| Completed | THE EFFECTS OF EARLY PERIOD KINESIOTAPE NCT06010264 | Kirsehir Ahi Evran Universitesi | N/A |
| Completed | Performance and Safety Evaluation of MD-Shoulder Collagen Medical Device in the Treatment of Rotator Cuff Synd NCT05489484 | Guna S.p.a | N/A |
| Completed | PMCF Study on the Safety, Performance and Clinical Benefits Data of the Quattro X Broadband NCT05690776 | Zimmer Biomet | — |
| Terminated | Anaverse™ Glenoid System and Its Instrumentation NCT05215600 | Zimmer Biomet | — |
| Recruiting | Slow and Accelerated Rehabilitation Protocols NCT05450510 | Hacettepe University | N/A |
| Completed | Pain Neuroscience Education Following Arthroscopic Rotator Cuff Repair NCT05277077 | Hacettepe University | N/A |
| Completed | Telerehabilitation in Individuals With Rotator Cuff Tear NCT05904249 | Istanbul University - Cerrahpasa | N/A |
| Completed | Rotator Cuff Tears Treated With Long Head of the Biceps Reinforcement NCT06664645 | Hospital Universitario Pedro Ernesto | N/A |
| Recruiting | Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Blo NCT04209504 | Duke University | — |
| Recruiting | Therapeutic Exercise for Rotator Cuff Tendinopathy / Subacromial Pain Syndrome - Outcomes and Mechanisms NCT04923477 | University of Southern California | N/A |
| Completed | Ultrasound After Total Shoulder Arthroplasty NCT04416932 | Duke University | — |
| Completed | Effect of Extracorporeal Shock Wave Therapy After Arthroscopic Rotator Cuff Repair NCT04848103 | Sahmyook University | N/A |
| Completed | Effectiveness of Low-level Laser Therapy NCT04836000 | Hacettepe University | N/A |
| Unknown | Frequency Analysis of the Ultrasound Images in Rotator Cuff Tendon NCT04859413 | National Taiwan University Hospital | — |
| Completed | Subacromial Bursa Re-Implantation After Rotator Cuff Repair NCT04634084 | The University of Texas Health Science Center, Houston | N/A |
| Completed | Physical Therapy Interventions Following Arthroscopic Rotator Cuff Repair NCT04711616 | Sahmyook University | N/A |
| Completed | The Effect of Pain Neuroscience Education on Patients With Arthroscopic Rotator Cuff Repair NCT04705311 | Sahmyook University | N/A |
| Unknown | Total Intravenous Anesthesia With Propofol vs. General Anesthesia in Outpatient Shoulder Arthroscopic Surgerie NCT04793022 | Carilion Clinic | Phase 4 |
| Completed | Evaluation of Mechanical Characteristics of Tendons of Athletes Using Sonography NCT05917483 | National Taiwan University Hospital | — |
| Unknown | Does Tranexamic Acid Improve Visualization During Arthroscopic Rotator Cuff Repair NCT04865380 | University of Saskatchewan | Phase 3 |
| Completed | Bupivacaine or Radiofrequency for Shoulder Pain NCT05778422 | Federal University of São Paulo | N/A |
| Terminated | REGENETEN™ Bioinductive Implant System in Full-thickness Tears NCT04450342 | Smith & Nephew, Inc. | N/A |
| Completed | Restoring the Anatomic Tension Relationship of the Long Head of the Biceps During Tenodesis NCT06571695 | Loyola University | N/A |
| Completed | Phase 1/2 Clinical Study of TPX-115 in Patients With Partial-Thickness Rotator Cuff Tear NCT04470167 | Tego Science, Inc. | Phase 1 / Phase 2 |
| Recruiting | The Effect of a Custom Pillow on Sleep Quality in Patients With Nonoperative Rotator Cuff Syndrome NCT05011331 | Rhode Island Hospital | N/A |
| Recruiting | Evaluation Of Outcomes Following Rotator Cuff Repair Using the REGENETEN Bioinductive Implant: A Prospective, NCT06857084 | Smith & Nephew, Inc. | — |
| Completed | TeleRehabilitation Following Arthroscopic Rotator Cuff Repair NCT04541953 | NYU Langone Health | N/A |
| Completed | Tranexamic Acid to Improve Arthroscopic Visualization in Shoulder Surgery NCT04594408 | Panam Clinic | Phase 4 |
| Completed | Inclusion of Mobilisation With Movement to an Exercise Programme in Rotator Cuff Related Pain NCT04175184 | Federal University of Health Science of Porto Alegre | N/A |
| Unknown | Cost-Effectiveness of Rotator Cuff Repair Methods NCT04146987 | Hospital Israelita Albert Einstein | N/A |
| Completed | The Effect of Cross-Education on Shoulder Arthroscopy NCT04470570 | Cedars-Sinai Medical Center | N/A |
| Completed | Effectiveness of Structured Closed Kinetic Chain and Video Based Game Exercise Program in Rotator Cuff Lesion NCT04426929 | Istanbul Medipol University Hospital | N/A |
| Completed | Comparison of Follow-up by Mobile App or Paper Questionnaire of Patients Undergoing Rotator Cuff Surgery NCT04359160 | L'Institut de Recherche en Chirurgie Orthopédique et Sportive | N/A |
| Completed | Mulligan and Proprioceptive Neuromuscular Fasciliation Techiniques in Rotator Cuff Pathology NCT06213584 | Istanbul University - Cerrahpasa | N/A |
| Unknown | Rotator Cuff Injury Managed With ERAS and Internet Plus Nursing NCT04927507 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Terminated | ASHCOM Shoulder System and Its Related Instruments NCT04258605 | Zimmer Biomet | — |
| Unknown | Demineralized Bone Matrix Rotator Cuff Study NCT04686396 | Arthrex, Inc. | N/A |
| Unknown | Exercise Program in Patients With Shoulder Pain and Rotator Cuff Tear NCT03962231 | Larissa Pechincha Ribeiro | N/A |
| Terminated | The Impact of a Preoperative Nerve Block on the Consumption of Sevoflurane in Total Shoulder Arthroplasty NCT04020601 | University of Alberta | Phase 2 / Phase 3 |
| Completed | Critical Shoulder Angle and Acromial Index on 3D Models NCT05742581 | Merve Sevgi INCE | — |
| Unknown | Irreparable Rotator Cuff Tears Treatment. Comparison of Two Methods: With and Without Biceps Tendon Augmentati NCT05001581 | Saint Lucas Hospital, Poland | N/A |
| Completed | Performance and Safety of the FIXIT® Anchor in Arthroscopic Rotator Cuff Repair NCT05720286 | Science and biomaterials | — |
| Completed | Myofascial Release in Shoulder Pathologies NCT04944446 | University of Cadiz | N/A |
| Completed | A Phase I/III Clinical Study of TPX-114 for the Treatment of Full-Thickness Rotator Cuff Tear NCT03668028 | Tego Science, Inc. | Phase 3 |
| Completed | A Pilot Randomized Trial of Pain Neuroscience Education in the Rehabilitation After Arthroscopic Rotator Cuff NCT04522934 | Universidad Católica del Maule | N/A |
| Completed | Automatic Multimodal Assessment of Occurrence and Intensity of Pain for Research and Clinical Use NCT04833244 | Manhattan Physical Medicine and Rehabilitation, LLP | N/A |
| Completed | Comparison of Two Arthroscopic Rotator Cuff Repair Techniques: Knot-tying Versus Knotless Suture-bridge Techni NCT03982108 | Koray Sahin | N/A |
| Completed | Do Relaxation Exercises Decrease Postoperative Pain After Arthroscopic Rotator Cuff Repair? NCT04249089 | Rothman Institute Orthopaedics | N/A |
| Completed | Dry Cupping Therapy on Rotator Cuff Injuries NCT05975801 | Istanbul Medipol University Hospital | N/A |
| Completed | Subacromial Corticosteroid Injections and tDCS in Rotator Cuff Tendinopathy NCT03967574 | Université de Sherbrooke | N/A |
| Completed | The Effects of Yoga on Patients With Rotator Cuff Injuries NCT02528084 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Completed | The Effect of Platelet Rich Plasma on Partial Thickness Rotator Cuff Tears: A Randomized Controlled Trial NCT04743986 | University of Calgary | Phase 4 |
| Completed | Hemiplegic Shoulder Pain and Rotator Cuff Injuries NCT02465853 | Chang Gung Memorial Hospital | N/A |
| Completed | Acellular Dermis in Rotator Cuff Repair NCT05458349 | The Royal Orthopaedic Hospital NHS Trust | N/A |