| Not Yet Recruiting | The Safety and Efficacy of Intravitreal Topotecan for the Treatment of Proliferative Vitreoretinopathy NCT06425419 | Massachusetts Eye and Ear Infirmary | Phase 1 |
| Withdrawn | UNITY VCS Vitreoretinal Surgery NCT07054281 | Alcon Research | N/A |
| Active Not Recruiting | Ocular Hypotony and Refractive Predictability in RRD Surgery NCT07283614 | Kazakh Eye Research Institute | N/A |
| Recruiting | hAM for Inferior RRD NCT07081945 | Eye & ENT Hospital of Fudan University | N/A |
| Recruiting | Treatment of Retinal Detachment in People Who Have Not Had Cataract Surgery With Vitrectomy vs Vitrectomy and NCT06997874 | Queen's University, Belfast | Phase 3 |
| Recruiting | Topical Netarsudil for the Prevention of Proliferative Vitreoretinopathy in Patients With Retinal Detachment NCT06033703 | Massachusetts Eye and Ear Infirmary | Phase 1 / Phase 2 |
| Recruiting | Comparison of Anatomical and Functional Outcomes of Laser Photocoagulation and Cryopexy in Patients with Rhegm NCT06694259 | Clinical Hospital Center, Split | N/A |
| Not Yet Recruiting | Foldable Capsular Scleral Buckling Versus Vitrectomy in Medium-complex Rhegmatogenous Retinal Detachment Treat NCT06610786 | Eye & ENT Hospital of Fudan University | N/A |
| Recruiting | Analysis of Risk Factors for High Intraocular Pressure and Retinal Detachment Recurrence After Vitrectomy with NCT06826573 | First Affiliated Hospital of Chongqing Medical University | — |
| Unknown | Comparative Study Between Three Different Techniques in Drainage of SRF During PPV in RRD NCT06324305 | Ain Shams University | N/A |
| Recruiting | Prevention of ProliFerative Vitreoretinopathy with Intravitreal MethotreXate in Primary Retinal DEtachment Rep NCT06541574 | Cincinnati Eye Institute, Southwest Ohio | Phase 2 |
| Terminated | Lamivudine and Plasma Markers of Inflammation in Retinal Detachment NCT06056596 | University of Wisconsin, Madison | EARLY_Phase 1 |
| Completed | Perfluorocarbon Liquid vs. Posterior Retinotomy During Pars-plana Vitrectomy for Rhegmatogenous Retinal Detach NCT06919211 | Benha University | N/A |
| Active Not Recruiting | A Multi-Center Study on the Use of Rho-Kinase Inhibitor to Reduce or Prevent PVR in RRD Eyes at High Risk for NCT05660447 | Wills Eye | Phase 2 / Phase 3 |
| Recruiting | Dropless Pars Plana Vitrectomy Study NCT05331664 | Massachusetts Eye and Ear Infirmary | Phase 4 |
| Completed | Primary Vitrectomy With Silicone Oil or SF6 for Rhegmatogenous Retinal Detachment NCT05377606 | Cairo University | N/A |
| Completed | Intravitreal Infliximab for Proliferative Vitreoretinopathy NCT04891991 | Cairo University | Phase 2 |
| Completed | Effects of 0.1% Nepafenac on Vitreous Inflammatory Biomarkers in Rhegmatogenous Retinal Detachment and Prolife NCT07162818 | Indonesia University | Phase 4 |
| Unknown | Early Prevention Strategies of Severe Proliferative Vitreoretinopathy Base on Precision Diagnosis of Single Ce NCT04520789 | Shanghai 10th People's Hospital | N/A |
| Unknown | Pneumatic Retinopexy for Primary Rhegmatogenous Retinal Detachment: To Steamroll or Not NCT04723420 | Sunnybrook Health Sciences Centre | N/A |
| Unknown | Treating Rhegmatogenous Retinal Detachment by Foldable Capsular Buckle NCT04571788 | Aier School of Ophthalmology, Central South University | — |
| Unknown | Combined Laser-surgical Technology of RRD Treatment NCT04403750 | The S.N. Fyodorov Eye Microsurgery State Institution | N/A |
| Completed | Healaflow Patch for the Treatment of Rhegmatogenous Retinal Detachment NCT03542162 | Tianjin Medical University Eye Hospital | N/A |
| Unknown | Combined Vitrectomy and Femtosecond Laser-assisted Cataract Surgery NCT05588037 | Aier School of Ophthalmology, Central South University | N/A |
| Unknown | Pneumatic Retinopexy Versus Vitrectomy for Retinal Detachment in Patients With Extended Criteria NCT02871531 | Unity Health Toronto | N/A |
| Completed | Prophylactic Intravitreal 5-Fluorouracil and Heparin to Prevent PVR in High-risk Patients With Retinal Detachm NCT02834559 | Universitätsklinikum Köln | Phase 3 |
| Completed | Ursodeoxycholic Acid for Rhegmatogenous Retinal Detachment NCT02841306 | Francine Behar-Cohen | Phase 1 |
| Unknown | Corneal Endothelial Cell Loss After Pneumatic Retinopexy for the Repair of Primary Rhegmatogenous Retinal Deta NCT02185469 | Sunnybrook Health Sciences Centre | N/A |
| Unknown | Axial Length Change in Eyes Treated by Silicone Sponge Scleral Buckling NCT01647373 | Meir Medical Center | — |
| Completed | Pneumatic Retinopexy Versus Vitrectomy for Retinal Detachment NCT01639209 | Unity Health Toronto | N/A |
| Unknown | Retinal Detachment - Demographic and Clinical Survey NCT01845571 | Medical University of Vienna | — |
| Completed | The Influence of Silicone Oil on Nerve Fiber Layer Thickness After Pars Plana Vitrectomy NCT01255306 | University Hospital Sestre Milosrdnice | — |
| Completed | Topographic Changes of Retinal Layers After Resolution of Acute Retinal Detachment NCT01587794 | Samsung Medical Center | — |
| Completed | Corneal Changes After Retinal Surgery NCT01446367 | Universidade Federal do Paraná | — |
| Completed | Anatomical and Functional Macular Changes in Retinal Detachment NCT01343134 | Centre Hospitalier Universitaire Dijon | — |
| Completed | Clinical Trial of Cryotherapy Versus Postoperative Laser Photocoagulation NCT01068379 | University of Campinas, Brazil | Phase 3 |
| Completed | Primary Vitrectomy With Endolaser or Encircling Band for Rhegmatogenous Retinal Detachment NCT00757536 | The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery | N/A |
| Completed | Macular Function After Scleral Buckle NCT00345007 | Singapore National Eye Centre | — |
| Unknown | Efficacy of Oral Colchicine in Prevention of Proliferative Vitreoretinopathy in Rhegmatogenous Retinal Detachm NCT00370201 | Shahid Beheshti University of Medical Sciences | Phase 3 |