Trials / Unknown
UnknownNCT04520789
Early Prevention Strategies of Severe Proliferative Vitreoretinopathy Base on Precision Diagnosis of Single Cell Sequencingvitreoretinopathy
Early Prevention Strategies of Severe Proliferative Vitreoretinopathy Base on Precision Diagnosis of Single Cell Sequencing
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- Sponsor
- Shanghai 10th People's Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 60 Years
- Healthy volunteers
- Not accepted
Summary
Study of initiating proliferative vitreoretinopathy (PVR)cell subtype (PVR initiating cells (PVR-IC) in RPE cells of rhegmatogenous retinal detachment (RRD) patients; to prove the percentage of PVR-IC decides the risk of serious PVR occurring after surgery; to investigate the safety and efficacy of early local steroids drug intervention in patients with severe postoperative PVR.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | RPE cell collection and single cell heterogeneity study | Study of initiating proliferative vitreoretinopathy (PVR)cell subtype (PVR initiating cells (PVR-IC) in RPE cells of rhegmatogenous retinal detachment (RRD) patients, the percentage of which decides the risk of serious PVR occurring after surgery. |
| PROCEDURE | Postoperative intervention | Early local steroids drug intervention in patients with severe postoperative PVR |
| PROCEDURE | Conventional Surgery for Retinal Detachment | Conventional Surgery for Retinal Detachment |
Timeline
- Start date
- 2020-09-01
- Primary completion
- 2022-06-30
- Completion
- 2022-12-31
- First posted
- 2020-08-20
- Last updated
- 2020-08-20
Source: ClinicalTrials.gov record NCT04520789. Inclusion in this directory is not an endorsement.