Clinical Trials Directory

Trials / Conditions / Recurrent Chronic Lymphocytic Leukemia

Recurrent Chronic Lymphocytic Leukemia

54 registered clinical trials studyying Recurrent Chronic Lymphocytic Leukemia9 currently recruiting.

StatusTrialSponsorPhase
RecruitingTesting the Effectiveness of the Anti-cancer Drug, Mirdametinib, in Treating Relapsed, Refractory Chronic Lymp
NCT07061951
National Cancer Institute (NCI)Phase 2
RecruitingAnti-CD19/20/22 Chimeric Antigen Receptor T Cells (TriCAR19.20.22 T Cells) for the Treatment of Relapsed or Re
NCT07166419
Ohio State University Comprehensive Cancer CenterPhase 1
RecruitingQ702 for the Treatment of Patients With Hematologic Malignancies
NCT06712810
Mayo ClinicPhase 1
RecruitingSonrotoclax, Rituximab, and Zanubrutinib in Treating Participants With Chronic Lymphocytic Leukemia, Small Lym
NCT06839053
Fred Hutchinson Cancer CenterPhase 2
TerminatedGenetically Engineered Cells (EGFRt/19-28z/IL-12 CAR T Cells) for the Treatment of Relapsed or Refractory CD19
NCT06343376
Roswell Park Cancer InstitutePhase 1
RecruitingB-Cell Activating Factor Receptor (BAFFR)-Based Chimeric Antigen Receptor T-Cells With Fludarabine and Cycloph
NCT06191887
Mayo ClinicPhase 1
RecruitingAcalabrutinib in Combination With Venetoclax for the Treatment of Refractory or Recurrent Chronic Lymphocytic
NCT04941716
Fred Hutchinson Cancer CenterPhase 2
RecruitingCD19-Directed CAR-T Cell Therapy for the Treatment of Relapsed/Refractory B Cell Malignancies
NCT04892277
Mayo ClinicPhase 1
WithdrawnIpilimumab, Ibrutinib, and Nivolumab for the Treatment of Chronic Lymphocytic Leukemia and Richter Transformat
NCT04781855
M.D. Anderson Cancer CenterPhase 1
RecruitingGenetically Engineered Cells (Anti-CD19/CD20/CD22 CAR T-cells) for the Treatment of Relapsed or Refractory Lym
NCT05418088
Sumithira VasuPhase 1
TerminatedDaratumumab and Ibrutinib for the Treatment of Relapsed or Refractory Chronic Lymphocytic Leukemia, DIRECT Stu
NCT04230304
Mayo ClinicPhase 2
CompletedCC-486, Lenalidomide, and Obinutuzumab for the Treatment of Recurrent or Refractory CD20 Positive B-cell Lymph
NCT04578600
Joseph TuscanoPhase 1
RecruitingAcalabrutinib and Venetoclax With or Without Early Obinutuzumab for the Treatment of High Risk, Recurrent, or
NCT04169737
M.D. Anderson Cancer CenterPhase 2
TerminatedCD19-Specific T Cells Post AlloSCT
NCT03579888
M.D. Anderson Cancer CenterPhase 1
Active Not RecruitingNivolumab for Relapsed, Refractory, or Detectable Disease Post Chimeric Antigen Receptor T-cell Treatment in P
NCT04205409
University of WashingtonPhase 2
Active Not RecruitingIntermittent Duvelisib Dosing in Treating Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymp
NCT03961672
City of Hope Medical CenterPhase 2
TerminatedSerial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial
NCT03878524
OHSU Knight Cancer InstitutePhase 1
WithdrawnRivogenlecleucel Donor Lymphocyte Immunotherapy in Treating Patients With Recurrent Blood Cancers After Stem C
NCT03807063
Fred Hutchinson Cancer CenterPhase 1
Active Not RecruitingModified Immune Cells (CD19/CD20 CAR-T Cells) in Treating Patients With Recurrent or Refractory B-Cell Lymphom
NCT04007029
Jonsson Comprehensive Cancer CenterPhase 1
WithdrawnModified Immune Cells (CD19-CD22 CAR T Cells) in Treating Patients With Recurrent or Refractory CD19 Positive,
NCT04029038
M.D. Anderson Cancer CenterPhase 1 / Phase 2
Active Not RecruitingPevonedistat and Ibrutinib in Treating Participants With Relapsed or Refractory CLL or Non-Hodgkin Lymphoma
NCT03479268
City of Hope Medical CenterPhase 1
Active Not RecruitingA Phase I/II Study to Evaluate the Safety of Cellular Immunotherapy Using Autologous T Cells Engineered to Exp
NCT03277729
Fred Hutchinson Cancer CenterPhase 1 / Phase 2
CompletedVenetoclax and Ibrutinib in Patients With Relapsed/Refractory CLL or SLL
NCT03045328
Steven E. CoutrePhase 2
TerminatedComparison of Triple GVHD Prophylaxis Regimens for Nonmyeloablative or Reduced Intensity Conditioning Unrelate
NCT03246906
Fred Hutchinson Cancer CenterPhase 2
CompletedMetformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chr
NCT02948283
City of Hope Medical CenterPhase 1
CompletedEntospletinib and Obinutuzumab in Treating Patients With Relapsed Chronic Lymphocytic Leukemia, Small Lymphocy
NCT03010358
Alexey Danilov, MDPhase 1 / Phase 2
CompletedIbrutinib in Treating Patients With Refractory or Relapsed Lymphoma After Donor Stem Cell Transplant
NCT02869633
Vanderbilt-Ingram Cancer CenterPhase 2
Active Not RecruitingVenetoclax and Ibrutinib in Treating Patients With Chronic or Small Lymphocytic Leukemia
NCT02756897
M.D. Anderson Cancer CenterPhase 2
TerminatedLenalidomide and Obinutuzumab in Treating Patients With Recurrent or Refractory Chronic Lymphocytic Leukemia o
NCT02225275
M.D. Anderson Cancer CenterPhase 2
WithdrawnIbrutinib or Idelalisib in Treating Patients With Persistent or Relapsed Chronic Lymphocytic Leukemia, Small L
NCT02662296
Fred Hutchinson Cancer CenterPhase 2
TerminatedMechanisms of Idelalisib-Associated Diarrhea in Patients With Relapsed Chronic Lymphocytic Leukemia, Indolent
NCT02928510
Jonsson Comprehensive Cancer Center
TerminatedBuparlisib and Ofatumumab or Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Le
NCT02614508
Emory UniversityPhase 1
CompletedEx Vivo-activated Autologous Lymph Node Lymphocytes in Treating Patients With Chronic Lymphocytic Leukemia
NCT02530515
M.D. Anderson Cancer CenterPhase 2
CompletedAdoptive Immunotherapy in Relapsed Hematological Malignancy: Early GVHD Prophylaxis
NCT02593123
Virginia Commonwealth UniversityPhase 2
TerminatedLenalidomide and AT-101 in Treating Patients With Relapsed B-Cell Chronic Lymphocytic Leukemia
NCT01003769
Mayo ClinicPhase 1 / Phase 2
CompletedNivolumab and Ibrutinib in Treating Patients With Relapsed, Refractory, or High-Risk Untreated Chronic Lymphoc
NCT02420912
M.D. Anderson Cancer CenterPhase 2
CompletedPembrolizumab Alone or With Idelalisib or Ibrutinib in Treating Patients With Relapsed or Refractory Chronic L
NCT02332980
Mayo ClinicPhase 2
Active Not RecruitingCellular Immunotherapy Following Chemotherapy in Treating Patients With Recurrent Non-Hodgkin Lymphomas, Chron
NCT02153580
City of Hope Medical CenterPhase 1
Active Not RecruitingLenalidomide, Ibrutinib, and Rituximab in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Le
NCT02160015
National Cancer Institute (NCI)Phase 1
Active Not RecruitingIbrutinib With or Without Rituximab in Treating Patients With Relapsed Chronic Lymphocytic Leukemia
NCT02007044
M.D. Anderson Cancer CenterPhase 2
CompletedLaboratory Treated T Cells in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Non-
NCT01865617
Fred Hutchinson Cancer CenterPhase 1 / Phase 2
CompletedIpilimumab or Nivolumab in Treating Patients With Relapsed Hematologic Malignancies After Donor Stem Cell Tran
NCT01822509
National Cancer Institute (NCI)Phase 1
UnknownNK Cells in Cord Blood Transplantation
NCT01619761
M.D. Anderson Cancer CenterPhase 1
CompletedLenalidomide and Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Sm
NCT01886859
National Cancer Institute (NCI)Phase 1
CompletedDonor Atorvastatin Treatment in Preventing Severe Acute GVHD After Nonmyeloablative Peripheral Blood Stem Cell
NCT01527045
Fred Hutchinson Cancer CenterPhase 2
CompletedRomidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver Dysfun
NCT01638533
National Cancer Institute (NCI)Phase 1
CompletedSirolimus, Cyclosporine, and Mycophenolate Mofetil in Preventing Graft-versus-Host Disease in Treating Patient
NCT01251575
Fred Hutchinson Cancer CenterPhase 2
CompletedGraft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated
NCT01231412
Fred Hutchinson Cancer CenterPhase 3
CompletedAutologous Peripheral Blood Stem Cell Transplant Followed by Donor Bone Marrow Transplant in Treating Patients
NCT01008462
Fred Hutchinson Cancer CenterPhase 2
CompletedFludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation, and Donor Bone Marrow Transplant Followed by
NCT00789776
Fred Hutchinson Cancer CenterPhase 1 / Phase 2
CompletedVorinostat, Cladribine, and Rituximab in Treating Patients With Mantle Cell Lymphoma, Relapsed Chronic Lymphoc
NCT00764517
OHSU Knight Cancer InstitutePhase 2
CompletedDonor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer
NCT00723099
Fred Hutchinson Cancer CenterPhase 2
CompletedFludarabine Phosphate and Total-Body Irradiation Before Donor Peripheral Blood Stem Cell Transplant in Treatin
NCT00060424
Fred Hutchinson Cancer CenterPhase 2
CompletedAutologous Stem Cell Transplant Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or R
NCT00005803
Fred Hutchinson Cancer CenterPhase 1 / Phase 2