Clinical Trials Directory

Trials / Conditions / Pyruvate Kinase Deficiency

Pyruvate Kinase Deficiency

13 registered clinical trials studyying Pyruvate Kinase Deficiency — 1 currently recruiting.

StatusTrialSponsorPhase
SuspendedClinical Trial to Evaluate the Efficacy of Gene Therapy for Pyruvate Kinase Deficiency
NCT06422351
Rocket Pharmaceuticals Inc.Phase 2
Enrolling By InvitationA Study to Provide Continued Access to Mitapivat for Participants Who Previously Completed an Agios-Sponsored
NCT05777993
Agios Pharmaceuticals, Inc.Phase 4
Active Not RecruitingAcquired Pyruvate Kinase Deficiency In Clonal Myeloid Neoplasms
NCT04902833
Massachusetts General Hospital—
TerminatedPyruvate Kinase (PK) Deficiency Global Longitudinal Registry: Patient-Reported Outcomes (PRO)
NCT04964323
Agios Pharmaceuticals, Inc.—
CompletedPyruvate Kinase Deficiency Global Longitudinal Registry Substudy of Protocol AG348-C-008
NCT04995315
Agios Pharmaceuticals, Inc.—
CompletedGene Therapy for Pyruvate Kinase Deficiency (PKD)
NCT04105166
Rocket Pharmaceuticals Inc.Phase 1
CompletedPyruvate Kinase Deficiency Epidemiological Study (PIECE)
NCT03866590
CENTOGENE GmbH Rostock—
CompletedExtension Study of AG-348 in Adult Participants With Pyruvate Kinase Deficiency Previously Enrolled in AG-348-
NCT03853798
Agios Pharmaceuticals, Inc.Phase 3
CompletedA Study to Evaluate Efficacy and Safety of AG-348 in Not Regularly Transfused Adult Participants With Pyruvate
NCT03548220
Agios Pharmaceuticals, Inc.Phase 3
CompletedA Study Evaluating the Efficacy and Safety of AG-348 in Regularly Transfused Adult Participants With Pyruvate
NCT03559699
Agios Pharmaceuticals, Inc.Phase 3
Active Not RecruitingPyruvate Kinase Deficiency Global Longitudinal Registry
NCT03481738
Agios Pharmaceuticals, Inc.—
CompletedA Study of AG-348 in Adult Participants With Pyruvate Kinase (PK) Deficiency
NCT02476916
Agios Pharmaceuticals, Inc.Phase 2
CompletedPyruvate Kinase Deficiency Natural History Study
NCT02053480
Boston Children's Hospital—