Clinical Trials Directory

Trials / Conditions / Prolymphocytic Leukemia

Prolymphocytic Leukemia

63 registered clinical trials studyying Prolymphocytic Leukemia5 currently recruiting.

StatusTrialSponsorPhase
RecruitingAllo HSCT Using RIC and PTCy for Hematological Diseases
NCT05805605
Masonic Cancer Center, University of MinnesotaPhase 2
RecruitingDonor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hemat
NCT04195633
Fred Hutchinson Cancer CenterPhase 2
RecruitingObservatory of Prolymphocytic Leukemia T
NCT04411043
French Innovative Leukemia Organisation
CompletedReduced Intensity Flu/Mel/TBI Conditioning for HAPLO HCT Patients With Hematologic Malignancies
NCT04191187
H. Lee Moffitt Cancer Center and Research InstitutePhase 2
RecruitingMyeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders
NCT03314974
Masonic Cancer Center, University of MinnesotaPhase 2
TerminatedComparison of Triple GVHD Prophylaxis Regimens for Nonmyeloablative or Reduced Intensity Conditioning Unrelate
NCT03246906
Fred Hutchinson Cancer CenterPhase 2
UnknownTreatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by Tandem CAR T Cells Targeting CD19 an
NCT03185494
Chinese PLA General HospitalPhase 1 / Phase 2
CompletedUCB Transplant for Hematological Diseases Using a Non Myeloablative Prep
NCT02722668
Masonic Cancer Center, University of MinnesotaPhase 2
CompletedTreatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by Tandem CAR T Cells Targeting CD19 an
NCT03097770
Chinese PLA General HospitalPhase 1 / Phase 2
CompletedAllo HSCT Using RIC for Hematological Diseases
NCT02661035
Masonic Cancer Center, University of MinnesotaPhase 2
TerminatedAdoptive TReg Cell for Suppression of aGVHD After UCB HSCT for Heme Malignancies
NCT02991898
Masonic Cancer Center, University of MinnesotaPhase 2
RecruitingUmbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases
NCT01962636
Masonic Cancer Center, University of MinnesotaN/A
WithdrawnIbrutinib or Idelalisib in Treating Patients With Persistent or Relapsed Chronic Lymphocytic Leukemia, Small L
NCT02662296
Fred Hutchinson Cancer CenterPhase 2
CompletedEx Vivo-activated Autologous Lymph Node Lymphocytes in Treating Patients With Chronic Lymphocytic Leukemia
NCT02530515
M.D. Anderson Cancer CenterPhase 2
CompletedShorter Course Tacro After NMA, Related Donor PBSCT With High-dose Posttransplant Cy for Hard-to-Engraft Malig
NCT02556931
Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsPhase 2
CompletedSelinexor and Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Aggre
NCT02303392
Jennifer WoyachPhase 1
WithdrawnSotrastaurin Acetate in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Small Lymp
NCT02285244
James BlachlyPhase 2
CompletedAcalabrutinib in Combination With Anti-CD20 and Venetoclax in Relapsed/Refractory or Untreated CLL/SLL/PLL
NCT02296918
Acerta Pharma BVPhase 1
Active Not RecruitingACP-196 (Acalabrutinib), a Novel Bruton Tyrosine Kinase (BTK) Inhibitor, for Treatment of Chronic Lymphocytic
NCT02029443
Acerta Pharma BVPhase 1 / Phase 2
CompletedPhase II MOR00208 in Combination With Lenalidomide for Patients With Relapsed or Refractory CLL, SLL or PLL or
NCT02005289
Ohio State University Comprehensive Cancer CenterPhase 2
Active Not RecruitingIbrutinib With or Without Rituximab in Treating Patients With Relapsed Chronic Lymphocytic Leukemia
NCT02007044
M.D. Anderson Cancer CenterPhase 2
UnknownTreatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by CART19
NCT01864889
Chinese PLA General HospitalN/A
UnknownGenetically Engineered Lymphocyte Therapy in Treating Patients With Lymphoma That is Resistant or Refractory t
NCT01735604
Chinese PLA General HospitalPhase 1 / Phase 2
TerminatedAllogeneic Stem Cell Transplant for CLL
NCT01629511
M.D. Anderson Cancer CenterPhase 1 / Phase 2
CompletedVaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing
NCT01588015
City of Hope Medical CenterPhase 1
CompletedDonor Atorvastatin Treatment in Preventing Severe Acute GVHD After Nonmyeloablative Peripheral Blood Stem Cell
NCT01527045
Fred Hutchinson Cancer CenterPhase 2
Active Not RecruitingPCI-32765 (Ibrutinib) in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Small Lym
NCT01589302
Kami Maddocks, MDPhase 2
WithdrawnMechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem Cell Transplant
NCT01558778
Roswell Park Cancer InstituteN/A
TerminatedLenalidomide With or Without Rituximab in Treating Patients With Progressive or Relapsed Chronic Lymphocytic L
NCT01419795
Fred Hutchinson Cancer CenterPhase 2
CompletedOfatumumab and Dinaciclib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Small
NCT01515176
National Cancer Institute (NCI)Phase 1 / Phase 2
CompletedProlonged or Standard Infusion of Cefepime Hydrochloride in Treating Patients With Febrile Neutropenia
NCT01484015
Wake Forest University Health SciencesPhase 1
CompletedMK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia
NCT01231919
National Cancer Institute (NCI)Phase 1
Active Not RecruitingInfection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic
NCT01199562
City of Hope Medical Center
CompletedSirolimus, Cyclosporine, and Mycophenolate Mofetil in Preventing Graft-versus-Host Disease in Treating Patient
NCT01251575
Fred Hutchinson Cancer CenterPhase 2
CompletedLenalidomide After Donor Bone Marrow Transplant in Treating Patients With High-Risk Hematologic Cancers
NCT01254578
National Cancer Institute (NCI)Phase 1
CompletedGraft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated
NCT01231412
Fred Hutchinson Cancer CenterPhase 3
CompletedStudy of Carfilzomib in Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL) or Prolymphocytic
NCT01212380
Ohio State University Comprehensive Cancer CenterPhase 1
CompletedAR-42 in Treating Patients With Advanced or Relapsed Multiple Myeloma, Chronic Lymphocytic Leukemia, or Lympho
NCT01129193
Amir MortazaviPhase 1
CompletedBortezomib and Azacitidine in Treating Patients With Relapsed or Refractory T-Cell Lymphoma
NCT01129180
Pierluigi PorcuPhase 1
TerminatedAlvespimycin Hydrochloride in Treating Patients With Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic
NCT01126502
National Cancer Institute (NCI)Phase 1
CompletedMassage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Canc
NCT01053494
Wake Forest University Health SciencesN/A
TerminatedCyclophosphamide, Alvocidib, and Rituximab in Treating Patients With High Risk B-Cell Chronic Lymphocytic Leuk
NCT01076556
National Cancer Institute (NCI)Phase 1
CompletedCART19 to Treat B-Cell Leukemia or Lymphoma That Are Resistant or Refractory to Chemotherapy
NCT01029366
University of PennsylvaniaPhase 1
CompletedSunitinib Malate in Treating HIV-Positive Patients With Cancer Receiving Antiretroviral Therapy
NCT00890747
National Cancer Institute (NCI)Phase 1
CompletedLenalidomide and Alvocidib in Treating Patients With Relapsed or Refractory B-cell Chronic Lymphocytic Leukemi
NCT00735930
National Cancer Institute (NCI)Phase 1
TerminatedObatoclax, Fludarabine, and Rituximab in Treating Patients With Previously Treated Chronic Lymphocytic Leukemi
NCT00612612
National Cancer Institute (NCI)Phase 1
CompletedDonor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies
NCT01093586
Case Comprehensive Cancer CenterPhase 2
TerminatedSunitinib in Treating Patients With Idiopathic Myelofibrosis
NCT00387426
National Cancer Institute (NCI)Phase 2
CompletedA Pilot Study to Evaluate the Co-Infusion of Ex Vivo Expanded Cord Blood Cells With an Unmanipulated Cord Bloo
NCT00343798
Fred Hutchinson Cancer CenterPhase 1
CompletedUmbilical Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patient
NCT00719888
Fred Hutchinson Cancer CenterPhase 2
CompletedMyeloablative Umbilical Cord Blood Transplantation in Hematological Diseases
NCT00309842
Masonic Cancer Center, University of MinnesotaPhase 2
TerminatedFlavopiridol in Treating Patients With Chronic Lymphocytic Leukemia or Prolymphocytic Leukemia
NCT00098371
National Cancer Institute (NCI)Phase 2
Terminated17-N-Allylamino-17-Demethoxygeldanamycin With or Without Rituximab in Treating Patients With Relapsed B-Cell C
NCT00098488
National Cancer Institute (NCI)Phase 1
CompletedFludarabine Phosphate, Radiation Therapy, and Rituximab in Treating Patients Who Are Undergoing Donor Stem Cel
NCT00104858
Fred Hutchinson Cancer CenterPhase 2
CompletedTacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone To
NCT00089011
Fred Hutchinson Cancer CenterPhase 2
CompletedCollecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With
NCT00898079
Children's Oncology Group
CompletedFludarabine Phosphate and Total-Body Irradiation Before Donor Peripheral Blood Stem Cell Transplant in Treatin
NCT00060424
Fred Hutchinson Cancer CenterPhase 2
CompletedCombination Chemotherapy Followed By Alemtuzumab in Treating Patients With Chronic Lymphocytic Leukemia or Pro
NCT00278213
German CLL Study GroupPhase 2
CompletedImatinib Mesylate in Treating Patients With Advanced Cancer and Liver Dysfunction
NCT00025415
National Cancer Institute (NCI)Phase 1
TerminatedArsenic Trioxide in Treating Patients With Relapsed or Refractory Lymphoma or Leukemia
NCT00005786
National Cancer Institute (NCI)N/A
CompletedFludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenola
NCT00112593
Fred Hutchinson Cancer CenterN/A
CompletedAutologous Stem Cell Transplant Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or R
NCT00005803
Fred Hutchinson Cancer CenterPhase 1 / Phase 2
TerminatedFludarabine, Cyclophosphamide, and Rituximab in Treating Patients With Prolymphocytic Leukemia
NCT00281931
German CLL Study GroupPhase 2