| Not Yet Recruiting | A Prospective Observational Trial to Assess Treatment Sequences and Factors That Impact Overall Sur-vival in P Chronic Lymphocytic Leukemia | — | 2026-01-01 |
| Recruiting | A Phase-3-trial of Acalabrutinib, Obinutuzumab & Venetoclax Compared to Obinutuzumab and Venetoclax in Previou Chronic Lymphocytic Leukemia | Phase 3 | 2022-04-19 |
| Completed | Efficacy of Acalabrutinib in Very Old or Frail Patients With Treatment-naïve or Relapsed/Refractory CLL Chronic Lymphoid Leukemia | Phase 2 | 2021-06-01 |
| Active Not Recruiting | Ibrutinib Monotherapy Versus Fixed-duration Venetoclax Plus Obinutuzumab Versus Fixed-duration Ibrutinib Plus Chronic Lymphoid Leukemia | Phase 3 | 2021-03-01 |
| Active Not Recruiting | Sequential Regimen of Bendamustine Followed by Obinutuzumab (GA101), Zanubrutinib (BGB-3111) and Venetoclax (A Chronic Lymphoid Leukemia | Phase 2 | 2020-10-01 |
| Recruiting | Efficacy and Safety of Zanubrutinib Plus Tislelizumab Treatment with or Without Sonrotoclax for Patients with Richter Transformation | Phase 2 | 2020-02-19 |
| Completed | Sequential Regimen of Bendamustin-Debulking Followed by Obinutuzumab, Acalabrutinib and Venetoclax in Patients Chronic Lymphoid Leukemia | Phase 2 | 2019-01-14 |
| Terminated | Obinutuzumab Containing Conditioning Regimen for Patients With Poor Risk CLL or Richter's Transformation Requi Chronic Lymphocytic Leukemia, Richter's Transformation | Phase 2 | 2017-11-13 |
| Completed | Standard Chemoimmunotherapy (FCR/BR) Versus Rituximab + Venetoclax (RVe) Versus Obinutuzumab (GA101) + Venetoc Chronic Lymphocytic Leukemia | Phase 3 | 2016-12-13 |
| Completed | Sequential Regimen of Bendamustin-Debulking Followed by Ofatumumab and Ibrutinib in CLL Patients (CLL2-BIO) Chronic Lymphocytic Leukemia | Phase 2 | 2016-02-04 |
| Completed | Sequential Regimen of Bendamustine-Debulking Followed by CAL-101 and GA101-Induction and -Maintenance in CLL ( Chronic Lymphocytic Leucemia | Phase 2 | 2015-05-28 |
| Completed | Sequential Regimen of Bendamustine-Debulking Followed by ABT-199 and GA101-Induction and -Maintenance in CLL ( Chronic Lymphocytic Leucemia | Phase 2 | 2015-05-06 |
| Completed | Sequential Regimen of Bendamustin [B] Followed by GA101 and Ibrutinib [I] in CLL Patients Chronic Lymphocytic Leucemia | Phase 2 | 2015-01-16 |
| Completed | Ibrutinib in Previously Untreated Binet Stage A Chronic Lymphocytic Leukemia With Risk of Disease Progression Chronic Lymphocytic Leukemia | Phase 3 | 2014-04-30 |
| Recruiting | Registry of the German CLL Study Group CLL, SLL, HCL | — | 2013-08-01 |
| Completed | A Study of Lenalidomide Maintenance for High-risk Patients With CLL Following First-line Therapy Chronic Lymphocytic Leukemia | Phase 3 | 2012-07-20 |
| Completed | A Safety and Efficacy Trial of a Combination of Bendamustine, Rituximab and Lenalidomide in Patients With Chro Chronic Lymphocytic Leukemia | Phase 1 / Phase 2 | 2011-02-01 |
| Completed | Combined Immunochemotherapy in Patients With T-Prolymphocytic Leukemia (T-PLL) T-cell-prolymphocytic Leukemia | Phase 2 | 2010-06-01 |
| Completed | FCR or BR in Patients With Previously Untreated B-Cell Chronic Lymphocytic Leukemia Chronic Lymphocytic Leukemia | Phase 3 | 2008-10-02 |
| Completed | Bendamustine and Rituximab in Treating Patients With Previously Untreated or Relapsed Chronic Lymphocytic Leuk Chronic Lymphocytic Leukemia | Phase 2 | 2005-11-01 |
| Completed | Rituximab, Fludarabine, and Cyclophosphamide or Observation Alone in Treating Patients With Stage 0, Stage I, Chronic Lymphocytic Leukemia | Phase 3 | 2005-10-01 |
| Terminated | Methotrexate Followed by Fludarabine in Patients With T-Cell Large Granular Lymphocytic Leukemia T-Cell Large Granular Lymphocytic Leukemia | Phase 2 | 2005-06-01 |
| Completed | Fludarabine, Cyclophosphamide, and Alemtuzumab in Patients With B-cell Chronic Lymphatic Leukemia (B-CLL) B-cell Chronic Lymphocytic Leukemia | Phase 2 | 2005-01-01 |
| Completed | Bendamustine and Mitoxantrone in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia Chronic Lymphocytic Leukemia | Phase 2 | 2004-10-01 |
| Completed | Fludarabine and Darbepoetin Alfa in Treating Older Patients With Chronic Lymphocytic Leukemia Chronic Lymphocytic Leukemia, Anemia | Phase 3 | 2004-09-01 |
| Completed | Alemtuzumab in Treating Patients With B-Cell Chronic Lymphocytic Leukemia Chronic Lymphocytic Leukemia | Phase 1 / Phase 2 | 2003-11-01 |
| Completed | Fludarabine or Chlorambucil as First-Line Therapy in Treating Older Patients With Previously Untreated Chronic Chronic Lymphocytic Leukemia | Phase 3 | 2003-09-01 |
| Completed | Combination Chemotherapy and Rituximab in Treating Patients With Chronic Lymphocytic Leukemia (CLL) That Did N Chronic Lymphocytic Leukemia | Phase 2 | 2003-04-01 |
| Completed | Combination Chemotherapy Followed By Alemtuzumab in Treating Patients With Chronic Lymphocytic Leukemia or Pro Prolymphocytic Leukemia | Phase 2 | 2002-09-01 |
| Completed | Alemtuzumab in Treating Patients With Advanced Chronic Lymphocytic Leukemia That Did Not Respond to Previous F Leukemia | Phase 2 | 2002-09-01 |
| Completed | Combination Chemotherapy, Total-Body Irradiation, and Alemtuzumab in Treating Patients Undergoing an Autologou Chronic Lymphocytic Leukemia | Phase 2 | 2001-06-01 |
| Completed | Fludarabine and Cyclophosphamide in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Chroni Chronic Lymphocytic Leukemia | Phase 1 / Phase 2 | 2000-06-01 |
| Terminated | Fludarabine, Cyclophosphamide, and Rituximab in Treating Patients With Prolymphocytic Leukemia Prolymphocytic Leukemia | Phase 2 | 1999-09-01 |
| Terminated | Combination Chemotherapy With or Without G-CSF in Treating Patients With Relapsed Chronic Lymphocytic Leukemia Chronic Lymphocytic Leukemia | Phase 3 | 1999-07-01 |
| Completed | Fludarabine With or Without Cyclophosphamide in Treating Patients With Advanced Chronic Lymphocytic Leukemia Chronic Lymphocytic Leukemia | Phase 3 | 1999-07-01 |
| Completed | Cyclophosphamide and Total Body Irradiation in Treating Patients Who Are Undergoing an Autologous Peripheral S Chronic Lymphocytic Leukemia | Phase 2 | 1998-01-01 |
| Completed | Fludarabine or Observation in Treating Patients With Stage 0, Stage I, or Stage II Chronic Lymphocytic Leukemi Chronic Lymphocytic Leukemia | Phase 3 | 1997-04-01 |