| Not Yet Recruiting | Vbeam Pro Pulse Dye Laser for the Treatment of Vascular Conditions NCT07290426 | Candela Corporation | N/A |
| Recruiting | A Study to Evaluate Efficacy and Safety of Light Dose in Subjects With PWB Treated With Hemoporfin PDT NCT05171894 | Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. | Phase 2 |
| Completed | Retrospective Cohort Study on the Impact of PDL Treatment History on the Efficacy of HMME-PDT in Treating PWS NCT06875492 | Second Affiliated Hospital of Xi'an Jiaotong University | — |
| Recruiting | Tolerability of 532 nm Laser Treatment of Port Wine Stains NCT05841628 | Massachusetts General Hospital | N/A |
| Unknown | KTP Laser vs Pulsed Dye Laser for Port-Wine Stains NCT05771311 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Unknown | Effect of Pulsed Dye Laser on Photodynamic Therapy of Port-Wine Stains NCT04536740 | Gang Ma | N/A |
| Completed | A Pilot Study of Hemoporfin PDT in Children(2-7 Years Old) With Port-wine Stain NCT04106258 | Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. | Phase 4 |
| Suspended | Pilot Study to Evaluate the Effect of Multiple Passes on Port Wine Stain Treatments With the Cutera Excel V™ L NCT04103164 | Massachusetts General Hospital | N/A |
| Completed | A New Approach in Laser Surgery Using the Regenerative Solution in Children Diagnosed With Vascular Pathology NCT04999618 | Center for Vascular Pathology, Moscow | Phase 4 |
| Terminated | Skin Imaging to Inform Laser Treatments NCT04336163 | University of California, Irvine | N/A |
| Completed | Postmarketing Safety Study of Hemoporfin in Patients With Port Wine Stain NCT03181984 | Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. | Phase 4 |
| Completed | A Pilot Study of Hemoporfin PDT in Children With Port-wine Stain NCT03125057 | Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. | Phase 4 |
| Completed | The Role of Angiogenesis-related Pathways in the Development of Port Wine Stains NCT03948997 | xjpfW | N/A |
| Terminated | Treatment of Port Wine Stains Using Pulsed Dye Laser, Erbium Yag Laser and Topical Sirolimus NCT02214706 | Erasmus Medical Center | N/A |
| Withdrawn | Effect of Laser Treatment on Capillary Malformations NCT02035319 | Children's Hospital Medical Center, Cincinnati | — |
| Completed | Novel Treatment for Port Wine Stain Birthmarks NCT01924273 | University of California, Irvine | Phase 1 |
| Completed | Pathogenic Mechanisms of Port Wine Stain and Repository of Port Wine Stain Biopsy Samples NCT02051101 | University of California, Irvine | N/A |
| Completed | Combined Bipolar Radiofrequency&Pulsed Dye Laser Treatment NCT01775722 | University of California, Irvine | N/A |
| Completed | Evaluate the Port-wine Stain Birthmark Treatment Before and After Pulsed Dye Laser Treatment NCT01774552 | University of California, Irvine | — |
| Completed | French National Cohort of Children With Port Wine Stain NCT01364857 | University Hospital, Tours | N/A |
| Withdrawn | Optical Frequency Domain Imaging (OFDI) in Dermatology NCT01438047 | Massachusetts General Hospital | — |
| Completed | Monitoring the Response of Port Wine Stain Birthmarks to Laser Therapy With Wide-field Functional Imaging Tech NCT01333553 | University of California, Irvine | — |
| Withdrawn | Pilot Study on the Use of the Matrix Radiofrequencyfor Treatment of Port Wine Stain Birthmarks NCT01166919 | University of California, Irvine | Phase 1 |
| Withdrawn | Combined Use of Pulsed Dye Laser and Topical Antiangiogenic Agents for Treatment of Port Wine Stain Birthmarks NCT00969397 | University of California, Irvine | Phase 1 / Phase 2 |
| Completed | A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks. NCT00830466 | University of California, Irvine | Phase 1 |
| Completed | A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks. NCT00800722 | University of California, Irvine | Phase 1 |
| Terminated | Personalized Interactive Laser Therapy of Port Wine Stain NCT00782483 | University of Arkansas | N/A |
| Withdrawn | Combined Pulsed Dye Laser and Topical Ranibizumab for Treatment of Port Wine Stain Birthmarks NCT00667472 | University of California, Irvine | Phase 1 |
| Withdrawn | Combined Alexandrite and Pulsed Dye Laser Treatment of Port Wine Stain Birthmarks NCT00580944 | University of California, Irvine | Phase 1 |
| Completed | Combining Topical Imiquimod 5% Cream With a Pulsed Dye Laser to Treat Port Wine Stain Birthmarks NCT00585247 | University of California, Irvine | N/A |
| Completed | Treatment of Naevus Flammeus Using Intense Pulsed Light and Pulsed Dye Laser NCT00365118 | Bispebjerg Hospital | N/A |
| Unknown | Evaluation and Optimization of the Technical and Clinical Performance of the Lumenis ONE Platform NCT00247299 | Rambam Health Care Campus | N/A |
| Completed | Optical Clearing of the Skin in Conjunction With Laser Treatments NCT00580736 | University of California, Irvine | Phase 1 |
| Completed | Measurement Skin Temperature During Pulsed Laser Exposure NCT00540917 | University of California, Irvine | Phase 2 |
| Completed | Dynamic Epidermal Cooling During Pulsed Dye Laser Treatment of Port Wine Stain Birthmark at High Fluences NCT00540371 | University of California, Irvine | — |
| Completed | Optical Biopsy of Human Skin in Conjunction With Laser Treatment NCT00540566 | University of California, Irvine | — |