NCT00540917

Measurement Skin Temperature During Pulsed Laser Exposure

Phase II Clinical Trial is to Compare Epidermal Temperature Measurements During 1.Laser Treatment at Standard Treatment Energies 2.Cryogen Spray Cooling (CSC) Plus Laser Treatment. 3.Contact Cooling Plus Laser Treatment.

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 118 (actual)
• Sponsor: University of California, Irvine · Academic / Other
• Sex: All
• Age: 7 Years – 75 Years
• Healthy volunteers: Accepted

Summary

Lasers are the treatment modality of choice for Port Wine Stain birthmarks.The epidermis is not totally spared due to partial absorption of energy therein by melanin that presents an optical barrier through which the light must pass to reach the underlying blood vessels. Absorption of laser energy by melanin causes localized heating in the epidermis, which may, if not controlled, produce permanent complications such as hypertrophic scarring or dyspigmentation.

Detailed description

The researchers want to establish a correlation between non-invasive skin temperature measurements and the minimum laser energy during skin laser treatment using cryogen spray cooling. This study would eliminate the need for test pulses to estimate the safe and acceptable radiant exposure prior to laser treatment.

Conditions

• Port-Wine Stain

Interventions

Type	Name	Description
PROCEDURE	cooling spray during laser treatment	skin temperature measurement

Timeline

• Start date: 2002-07-01
• Primary completion: 2010-03-01
• Completion: 2010-03-01
• First posted: 2007-10-08
• Last updated: 2022-11-01

Locations

1 site across 1 country: United States