| Recruiting | Pediatric Pilonidal Sinus Surgical Treatment NCT07369921 | Zeliha Alicikus | N/A |
| Not Yet Recruiting | Sacral Erector Spinae Plane Block in Pilonidal Sinus Surgery NCT07534488 | Medipol University | N/A |
| Recruiting | Prospective Study in Laser Treatment of Pilonidal Cysts NCT07314632 | Centre Hospitalier Departemental Vendee | — |
| Not Yet Recruiting | SiLaC Laser Technique for Pilonidal Sinus - La Paz Cohort Study. NCT07260643 | Hospital Universitario La Paz | — |
| Recruiting | Bascom Cleft Lift for Primary Wound Healing in Complex and Recurrent Sacrococcygeal Pilonidal Sinus Disease NCT06683274 | Albert Schweitzer Ziekenhuis, Netherlands | — |
| Recruiting | Topical Anti-Androgens in Pilonidal Sinus Disease NCT06286397 | University of Pennsylvania | Phase 2 |
| Recruiting | ENVELOP: Wound Care Following Pilonidal Sinus Surgery NCT06647290 | Royal College of Surgeons, Ireland | N/A |
| Recruiting | Comparison of Pit Picking, Phenol and Combined Pit Picking and Phenol Applications in Pilonidal Sinus Treatmen NCT06517472 | Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital | — |
| Not Yet Recruiting | Comparing Minimally Invasive Treatments for Pilonidal Disease: LA POPA Trial (Laser And Pit-picking OR Pit-pic NCT06140199 | dr. IJM Han-Geurts | N/A |
| Recruiting | Outcomes of Karydakis, Primary Closure, and Pit Picking Methods in the Treatment of Pilonidal Sinus: A Prospec NCT06518499 | Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital | — |
| Recruiting | Pilonidal Sinus Disease NCT06508086 | Sohag University | N/A |
| Recruiting | The Role of Mesenchymal Stem Cell and Exosome in Treating Pilonidal Sinus Disease in Children NCT06391307 | Mustafa Azizoğlu | N/A |
| Unknown | Comparative Study Between Wide Local Excision and Minimal Excision of Pilonidal Sinus NCT06021392 | Abanoub emad fayez | — |
| Recruiting | The Efficacy of Combining Platelet-rich Plasma With Crystallized Phenol in Pilonidal Sinus Disease NCT06324656 | Necmi Kadıoğlu Hospital | N/A |
| Completed | Effect of Sacral Erector Spinae Plane Block on Hemorrhoid and Pilonidal Sinus Surgery NCT06459739 | Erzincan Binali Yildirim Universitesi | N/A |
| Unknown | Pudendal Nerve Block With Bupivacaine Alone and Bupivacaine With Methylene Blue for Postoperative Analgesia NCT05990569 | Nepal Mediciti Hospital | N/A |
| Unknown | PILONIDAL SINUS: CONVENTIONAL CARE VERSUS NEGATIVE PRESSURE THERAPY. NCT05474911 | Sebastiano Biondo | N/A |
| Unknown | Karydakis Flap Versus Burow's Triangle Advancement Flap in the Surgery of Sacrococcygeal Pilonidal Sinus Disea NCT05289297 | Istanbul Sultanbeyli State Hospital | N/A |
| Completed | Comparative Analysis of Hypobaric Versus Hyperbaric Bupivacaine for Spinal Anesthesia in Day-Case Anorectal Su NCT05409820 | Ankara City Hospital Bilkent | — |
| Recruiting | Myriad™ Augmented Soft Tissue Reconstruction Registry NCT05243966 | Aroa Biosurgery Limited | — |
| Completed | Effect of Platelet Rich Plasma (PRP) on Healing Time in Patients Following Pilonidal Sinus Surgery NCT06206330 | İsmail Oskay Kaya | N/A |
| Unknown | Metronidazole Ointment in Non-healing Pilonidal Sinus Wounds NCT04273997 | S.L.A. Pharma AG | Phase 2 |
| Completed | Clinical Trial to Test the Phenolization in Sacrococcygeal Pilonidal Disease NCT05404243 | HJ23 | Phase 4 |
| Completed | The Most Frequently Preferred Surgical Method In The Treatment Of Sacrococcygeal Pilonidal Disease NCT04599517 | Konya Meram State Hospital | — |
| Unknown | Endoscopic Pilonidal Sinus Treatment (EPSIT) Versus Sinus Laser Closure (SiLaC) Versus Lay Open Technique NCT04418336 | Mansoura University | N/A |
| Unknown | Comparison of Karydakis and Limberg Flap Treatment of Pilonidal Sinus in Adolescent. a Prospective, Randomised NCT04217824 | Kahramanmaras Sutcu Imam University | N/A |
| Unknown | Non-Powered Negative Pressure Wound Therapy vs Open Technique for Pilonidal Disease NCT03483480 | The National Children's Hospital, Tallaght | N/A |
| Completed | Application of Platelet-rich Plasma in Pilonidal Sinus Disease NCT04697082 | Cihangir Akyol | N/A |
| Completed | Karydakis Procedure Vs Limberg Flap in Treatment of Sacrococcygeal Pilonidal Sinus NCT03765086 | Services Hospital, Lahore | N/A |
| Unknown | GLUtEus Maximus Fascia Plasty Flap for Pilonidal Sinus NCT03914729 | Russian Society of Colorectal Surgeons | N/A |
| Completed | Lateral Advancement Flap Versus Classic Limberg Flap in The Treatment Of NonComplicated Pilonidal Sinus NCT04572919 | Zagazig University | N/A |
| Completed | Pilonidal Sinus Disease: Preliminare Study NCT03764657 | Ospedale di Cavalese | — |
| Completed | Minimally Invasive Treatment Methods for Pilonidal Disease NCT03070028 | Uşak University | N/A |
| Unknown | Sacrococcygeal Local Anesthesia With Different Doses of Clonidine for Pilonidal Sinus Surgery NCT02539693 | Makassed General Hospital | N/A |
| Completed | Comparison of Two Different Flap Methods in the Treatment of Pilonidal Sinus Disease NCT05851690 | Atlas University | N/A |
| Completed | Pilonidal Excision Versus Endoscopic Surgery NCT03923621 | St Helens & Knowsley Teaching Hospitals NHS Trust | N/A |
| Completed | Combined Open and Closed Approach for Management of Pilonidal Sinus by Special U-shaped Sutures Without Drain. NCT04017260 | Zagazig University | N/A |
| Completed | Asymmetric Primary Closure and Additional Skin Excision Technique. NCT03424057 | Siverek Devlet Hastanesi | N/A |
| Unknown | Feasibility of a Novel Technique for Pilonidal Wound Healing NCT02330159 | Southeast Clinical Research Associates, Houston, Texas | — |
| Completed | Off-midline Closure Errors as a Risk Factor for Recurrence Following Limberg Flap in Patients With Pilonidal S NCT02663466 | Medical Park Gaziantep Hospital | — |
| Completed | A Single Center Experience in the Management of Pilonidal Disease NCT05892198 | Mansoura University | N/A |
| Completed | Endoscopic Pilonidal Sinus Treatment With Additional Crystalized Phenol NCT02277340 | Ankara University | Phase 1 |
| Completed | Reduction Dead Space Volume With Karydakis Modification NCT02574936 | Siverek Devlet Hastanesi | N/A |
| Unknown | Video Assisted Ablation of Pilonidal Sinus NCT01963273 | Federico II University | N/A |
| Unknown | Crystallized Phenol Versus Transposition Flaps for Treatment of Pilonidal Disease: A Prospective Study NCT01792557 | S.B. Konya Education and Research Hospital | N/A |
| Completed | Umbilical Pilonidal Sinus: a Case Report NCT03007173 | Medical Park Gaziantep Hospital | — |
| Terminated | Fistulectomy vs. Modified Karydakis Procedure for Pilonidal Sinus NCT03271996 | Dimitri Christoforidis | N/A |
| Completed | Bilateral Gluteal Fascio-myo-cutaneous Flap in Treatment of Recurrent Pilonidal Disease NCT02621879 | Mansoura University | N/A |
| Completed | Umblical Pilonidal Sinus Evaluation NCT04856605 | Istanbul Medeniyet University | — |
| Completed | Effectiveness of Methylene Blue Guidance in Total Excision of Pilonidal Sinus. NCT01513382 | Bezmialem Vakif University | N/A |
| Unknown | Bascom Cleft Lift Versus Limberg Flap for Sacrococcygeal Pilonidal Sinus NCT01337869 | Trabzon Numune Training and Research Hospital | N/A |
| Completed | Staging System for Chronic Symptomatic Pilonidal Sinus Disease NCT02712970 | Trabzon Numune Training and Research Hospital | — |
| Completed | Study on Surgical Treatment of Pilonidal Sinus Disease NCT02849197 | Bezmialem Vakif University | — |
| Completed | A Preliminary, Non-comparative Study to Evaluate a Bioresorbable Wound Scaffold in Acute Wounds NCT01081522 | ConvaTec Inc. | — |
| Completed | Use of Plasma Rich in Growth Factors (PRGF) in Pilonidal Sinus Excision NCT02246192 | Hospital Quiron Sagrado Corazon | N/A |
| Completed | Ghnnam Excision Technique for Pilonidal Sinus NCT01399320 | Mansoura University | Phase 1 |
| Completed | Karydakis Procedure Versus Excision With Healing by Secondary Intention (EHSI) in Sacrococcygeal Pilonidal Sin NCT00716937 | Tehran University of Medical Sciences | Phase 4 |
| Completed | Long-term Outcome After Cleft-lift for Pilonidal Sinus Disease NCT05356208 | Nordsjaellands Hospital | — |
| Unknown | Pore Excision, Curettage, and Injection of Cymetra for Pilonidal Disease NCT00493493 | Matino, James, M.D. | N/A |
| Completed | Limberg-flap: Prospective Data Collection NCT00672555 | Cantonal Hospital of St. Gallen | N/A |
| Completed | Mid-line Excision Versus Karydakis Operation for Pilonidal Sinus NCT00412659 | Umeå University | Phase 2 / Phase 3 |
| Completed | Primary Wound Closure Using a Limberg Flap Versus Secondary Wound Healing Following Pilonidal Sinus Excision NCT01889394 | Kantonsspital Liestal | N/A |
| Completed | Conservative Versus Surgical Treatment of Umbilical Pilonidal Disease NCT01662765 | Medical Park Gaziantep Hospital | N/A |
| Completed | Comparison Between Laying Open and Sinus Excision of Pilonidal Sinus - a Randomized Study NCT00997048 | Uppsala University | N/A |
| Completed | Nonoperative Treatment of Recurrent Pilonidal Sinus Disease NCT04423510 | Osman DOĞRU | — |