NCT02246192

Use of Plasma Rich in Growth Factors (PRGF) in Pilonidal Sinus Excision

Application of PRGF (Plasma Rich in Growth Factors) to Reduce the Healing Time After Pilonidal Sinus Excision. A Randomized 5-years Prospective Controlled Trial.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 51 (actual)
• Sponsor: Hospital Quiron Sagrado Corazon · Academic / Other
• Sex: All
• Age: 13 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The use of plasma rich in growth factors in wound excision pilonidal sinus could improve the healing process of the wound, when compared with the usual technique of daily local healing. The investigators propose the objective of evaluating the efficacy of intra- and postoperative application of plasma rich in growth factors, to reduce healing time and complications, arising from its removal, compared to the standard surgical treatment.

Detailed description

prospective randomized control trial, comparing PRGF application vs daily local care(betadine +saline) in sinus pilonidal wound excision. PRGF is extracted from de patient blood and infiltrated in the pilonidal wound every week. this treatment is compared with betadine and saline wound care in terms of wound healing time, pospoperative pain and other complications. this study try to keeps the advantages of using open technique for pilonidal desease( low recurrence rate and surgical site infections) and improving the disadvantages (high wound healing time and postperative pain with wore quality of life) when it´s compared with direct closure or flap techniques.

Conditions

• Pilonidal Sinus

Interventions

Type	Name	Description
PROCEDURE	sinus pilonidal excision+ PRGF	open sinus pilonidal excision and plasma rich grow factor infiltration intra and postoperatively
PROCEDURE	sinus pilonidal excision and standard cares	sinus pilonidal excision and postoperative standard care with povidone daily

Timeline

• Start date: 2008-11-01
• Primary completion: 2014-01-01
• Completion: 2014-01-01
• First posted: 2014-09-22
• Last updated: 2015-03-19