| Not Yet Recruiting | Reaching Calm: A Digital Intervention to Prevent Perinatal Anxiety Disorders NCT07458698 | University of Massachusetts, Worcester | N/A |
| Not Yet Recruiting | Efficacy of Yoga-Based Intervention in Improving Mother-Child Bonding in Maternal Depression NCT07515222 | All India Institute of Medical Sciences | N/A |
| Recruiting | Pathways to Perinatal Mental Health Equity NCT06790641 | University of Massachusetts, Worcester | N/A |
| Not Yet Recruiting | Center M Randomized Trial NCT07304895 | Oregon Health and Science University | N/A |
| Recruiting | Testing "Doula Link", a Multi-Component Intervention to Improve Perinatal Mental Health NCT07217561 | Beth Israel Deaconess Medical Center | N/A |
| Active Not Recruiting | Group Cognitive Behavioural Therapy for Paternal Perinatal Depression NCT07166237 | McMaster University | N/A |
| Recruiting | Accelerated TMS for Perinatal Depression NCT06968390 | Brigham and Women's Hospital | N/A |
| Not Yet Recruiting | Clinical and Cost-effectiveness of an Online Self-help Intervention and a Face-to-face Intervention Versus Usu NCT07027761 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Recruiting | Feasibility Study and Pilot Hybrid Effectiveness-Implementation Trial for the Universal Prevention of Maternal NCT06640907 | University of Seville | N/A |
| Not Yet Recruiting | Preventing Perinatal Depression with an App-Based CBT Program NCT06672432 | Jintang County Maternal and Child Health Hospital | N/A |
| Recruiting | Validation of the French Version of the Perinatal Assessment of Paternal Affectivity (PAPA) NCT06594263 | University Hospital, Clermont-Ferrand | — |
| Recruiting | TrueBlue Clinical Study - Investigating the Use of a Mobile Phone App TrueBlue for Monitoring Depression and A NCT06364488 | BlueSkeye AI | N/A |
| Recruiting | A Chinese Version of the Thinking Health Program for East Asian Pregnant Immigrant People in Canada NCT06446089 | Queen's University | N/A |
| Completed | Study of the Intervention Effect of Self-help Training Camps in Promoting Mental Health Among Perinatal Women NCT06405932 | Fangbiao Tao | N/A |
| Recruiting | Perinatal Depression & Anxiety (PDA) and Maternal Gut Microbiome NCT06074250 | The Canadian College of Naturopathic Medicine | Phase 2 / Phase 3 |
| Recruiting | Maternal Well-being in the Perinatal Period NCT06473935 | IRCCS San Raffaele | — |
| Enrolling By Invitation | A Randomized Controlled Trial of the "Psychological Training Camp & Obstetrician-Led Psychoprenatal Interventi NCT06383221 | Fangbiao Tao | N/A |
| Unknown | Feasibility and Acceptability of a Telehealth Intervention Among Women With Perinatal Mental Health NCT05832424 | Boise State University | N/A |
| Recruiting | Supporting At-Risk Mothers Across Perinatal Period NCT06363019 | National University of Singapore | N/A |
| Recruiting | The Relationship Between Maternal Perinatal Depression and Feeding Behavior Among Primiparas NCT06231602 | National Taiwan University Hospital | — |
| Completed | Daring Birth - Digital Coaching Solution to Improve Childbirth Experience NCT06585839 | Aalto University | N/A |
| Completed | Center M: Digital Health Innovation Pilot NCT06000449 | Oregon Health and Science University | N/A |
| Recruiting | Gestational Diabetes and Perinatal Depression: an Intervention Program NCT05800509 | National Taiwan University Hospital | N/A |
| Unknown | Genetic Risk Factors Predictive of the Occurrence of Maternally Diagnosed Perinatal Depression in Women NCT05175755 | Fondation Hôpital Saint-Joseph | N/A |
| Recruiting | Feasibility and Acceptability of a Novel Cognitive Behavioral Skills Mobile App for Pregnant and Postpartum In NCT05897619 | Weill Medical College of Cornell University | N/A |
| Completed | Cognitive Behavioral Couple Therapy for Perinatal Distress NCT06001021 | Sameera Shafiq | N/A |
| Recruiting | Brief Cognitive Behavioural Therapy for Insomnia Versus Sleep Hygiene for Sleep Difficulties in Early Pregnanc NCT05710991 | St. Joseph's Healthcare Hamilton | N/A |
| Unknown | Hybrid Health Education Intervention Integrated Within a Mental Health Package for Adolescent Perinatal Depres NCT06154655 | University of Ibadan | N/A |
| Recruiting | Perinatal Depression and Adverse Childhood Experiences: Prevention Trial NCT05795114 | Northwestern University | N/A |
| Active Not Recruiting | Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women NCT05552053 | Cedars-Sinai Medical Center | Phase 2 / Phase 3 |
| Recruiting | Maternal Mental Health Access - MaMa NCT06049433 | University of Utah | N/A |
| Completed | Pilot Study of Mothers and Babies Online in Home Visiting NCT05714956 | Northwestern University | N/A |
| Completed | Reducing Stress-Sensitive Problems Among Pregnant Black Women With Childhood Adversity NCT05718479 | University of Illinois at Chicago | N/A |
| Unknown | Perinatal Mental Health for Refugee Women NCT05654987 | Universidad Nacional de Educación a Distancia | — |
| Completed | Effect of 'Parentbot - a Digital Healthcare Assistant (PDA)' in Improving Parenting Outcomes During the Perina NCT05463926 | National University of Singapore | N/A |
| Unknown | "Thinking Healthy Programme" for Perinatal Depression in Nepal NCT05393479 | Transcultural Psychosocial Organization Nepal | N/A |
| Completed | Baby2Home (B2H) Mobile Health Application NCT05595486 | Women and Infants Hospital of Rhode Island | N/A |
| Active Not Recruiting | The DC Mother-Infant Behavioral Wellness Program NCT05345834 | Children's National Research Institute | N/A |
| Unknown | Global Mental Health of Urban Mothers NCT04363177 | Karolinska Institutet | N/A |
| Active Not Recruiting | mHealth Mindfulness Intervention for Pregnant Black and Latina Women at Risk of Postpartum Depression NCT05186272 | Kaiser Permanente | Phase 3 |
| Completed | Thinking Healthy Program-Technology Assisted (THP-TA) NCT05353491 | Human Development Research Foundation, Pakistan | N/A |
| Completed | The SUPPORT Study: Effectiveness and Usability of a Web-Enabled Resource for Postpartum Mental Health NCT05382884 | University of British Columbia | Phase 2 |
| Completed | MomMoodBooster VA Program NCT05196152 | University of Iowa | N/A |
| Unknown | Exposures to Perinatal Adverse Experiences: Multimodal Omics Signature of Stress Vulnerability and Resilience NCT05951738 | IRCCS Centro San Giovanni di Dio Fatebenefratelli | N/A |
| Completed | Peer Mentor Texting NCT07380061 | University of Washington | N/A |
| Completed | The Feasibility of an Online Intergenerational Co-parenting Program NCT05119062 | The Hong Kong Polytechnic University | N/A |
| Completed | Accelerating Implementation of Mindful Mood Balance for Moms NCT04846504 | Kaiser Permanente | N/A |
| Terminated | Maternal Telemental Health Interventions in Response to Covid-19* NCT04594525 | Hamad Medical Corporation | N/A |
| Completed | Preventing Perinatal Depression NCT06525922 | Oregon Health and Science University | N/A |
| Withdrawn | Prospective Study Evaluating a Novel Mobile App Based Preventive Behavioral Intervention for Perinatal Mood Di NCT04914299 | Massachusetts General Hospital | N/A |
| Completed | MoodUP in Improving Psychological Outcomes Among Perinatal Women NCT03970057 | National University of Singapore | N/A |
| Active Not Recruiting | Elevating Voices, Addressing Depression, Toxic Stress and Equity in Group Prenatal Care NCT04838210 | Washington University School of Medicine | N/A |
| Completed | Evaluating Overcoming Anxiety in Pregnancy and Postpartum as an Online Self-Directed Program NCT04844138 | University of Manitoba | N/A |
| Completed | A Pilot Randomized Trial of Video-based Family Therapy for Depressed Home Visited Mothers NCT04741776 | Dartmouth-Hitchcock Medical Center | N/A |
| Completed | New Moms Mood Tracking & Wellbeing NCT05056454 | University of California, Los Angeles | N/A |
| Completed | Addressing Perinatal Depression in Deprived Areas of Istanbul, Turkey NCT04819711 | Perran Boran | N/A |
| Completed | The Stony Brook University Calm-Mom Study NCT04018625 | Stony Brook University | N/A |
| Unknown | Collaborative Care for Perinatal Depression Care in Vietnam NCT04650334 | University of Washington | N/A |
| Completed | "Mamma Mia" for Perinatal Health and Wellness NCT04300894 | Virginia Commonwealth University | N/A |
| Completed | A Smartphone-Assisted Brief Behavioral Intervention for Pregnant Women With Depression NCT04495166 | University of Sao Paulo | N/A |
| Completed | Efficacy of Brief Acceptance and Commitment Therapy (ACT) for Perinatal Anxiety NCT03837392 | University of Iowa | N/A |
| Completed | Telehealth Group Intervention for Perinatal Depressive Symptoms NCT03932760 | University of Utah | N/A |
| Completed | A Common Elements-based Intervention to Improve Maternal Psychological Well-being and Mother-infant Interactio NCT04252807 | Human Development Research Foundation, Pakistan | N/A |
| Completed | CSF/Serum Biomarkers in Predicting PND/Persistent Pain After Cesarean NCT04271072 | Duke University | — |
| Completed | Scaling Up Maternal Mental Healthcare by Increasing Access to Treatment (SUMMIT) NCT04153864 | Mount Sinai Hospital, Canada | N/A |
| Completed | Characterizing the Neural Substrates of Irritability in Women: an Experimental Neuroendocrine Model NCT04051320 | University of North Carolina, Chapel Hill | Phase 2 |
| Recruiting | Implementation of Prevention and Intervention of Maternal Perinatal Depression to Strengthen Maternal and Chil NCT04069091 | Katri Räikkönen | N/A |
| Completed | Adaptation of the Friendship Bench Intervention for HIV-infected Perinatal Women in Lilongwe NCT04143009 | University of North Carolina, Chapel Hill | N/A |
| Completed | A Pilot Trial of Perinatal Depression Treatment in HIV Infected Women NCT04094870 | University of North Carolina, Chapel Hill | Phase 4 |
| Completed | Dialectical Behavior Therapy for Pregnant Women NCT03938350 | Emory University | N/A |
| Unknown | Cohort Study on the Outcome and Influencing Factors of Perinatal Depression NCT04517981 | Shanghai Mental Health Center, Jingan District | — |
| Completed | Development and Evaluation of SM-ART Intervention (SM-ART) NCT04694261 | Aga Khan University | N/A |
| Completed | The Role of Sex Steroids and Serotonin Brain Dynamics in Perinatal Mental Health NCT03795688 | Vibe G Frøkjær, MD, PhD | — |
| Completed | Responsive e-Health Intervention for Perinatal Depression in Healthcare Settings NCT03995316 | Oregon Research Behavioral Intervention Strategies, Inc. | N/A |
| Completed | Development, Feasibility and Acceptability of Fathers and Babies (FAB): A Pilot Study NCT03427528 | Northwestern University | N/A |
| Completed | Low-dose Ketamine and Postpartum Depression in Parturients With Prenatal Depression NCT03336541 | Peking University First Hospital | Phase 4 |
| Completed | Virtual Psychiatric Care for Perinatal Depression NCT03291600 | Women's College Hospital | N/A |
| Completed | Integrating Text Messages Into the Mothers and Babies Course NCT03420755 | Northwestern University | N/A |
| Unknown | Remote Supervision for Implementing Collaborative Care for Perinatal Depression NCT02976025 | University of Washington | N/A |
| Completed | Comparing the Effectiveness of Clinicians and Paraprofessionals to Reduce Disparities in Perinatal Depression NCT02979444 | Northwestern University | N/A |
| Completed | PRogram In Support of Moms (PRISM): A Pilot Study NCT02935504 | University of Massachusetts, Worcester | N/A |
| Completed | Medicaid Enhanced Prenatal/Postnatal Services Using a Nurse-Community Health Worker Team NCT00536159 | Michigan State University | N/A |