| Not Yet Recruiting | Catheter Ablation Using a Novel Navigation and Imaging System NCT06895187 | LUMA Vision Ltd. | — |
| Recruiting | REPRESENT-PF Registry NCT07535268 | Vivek Reddy | — |
| Recruiting | Evaluation of Novel Waveforms Delivered Using the FARAPULSE™ PFA System NCT07444320 | Boston Scientific Corporation | N/A |
| Recruiting | Determinates of Atrial Tracking and Prevalence of Atrial Fibrillation in the Micra AV2 (DANCE AFIB) NCT07344961 | Northwell Health | — |
| Not Yet Recruiting | Pulsed Field Ablation of SVC and PV in Paroxysmal Atrial Fibrillation (PASPA Study) NCT07191626 | Changhai Hospital | N/A |
| Recruiting | Burst Stimulation for Paroxysmal Atrial Fibrillation NCT07281898 | Zhibing Lu | N/A |
| Recruiting | A Study Assessing Arrhythmia Mapping With a Multi-Electrode Mapping Catheter NCT07116525 | Biosense Webster, Inc. | N/A |
| Active Not Recruiting | Pragmatic Evaluation of a Pentaspline Pulsed Field Ablation System to Treat Atrial Fibrillation and Related Ar NCT06765356 | Vivek Reddy | Phase 4 |
| Recruiting | EXercise Cardiac Magnetic Resonance Assessment of Left Atrial Mechanics Following Ablation NCT06212791 | Virginia Commonwealth University | — |
| Completed | ADVENT Trial Long Term Outcomes Evaluating Atrial Fibrillation Progression Study NCT06526546 | Boston Scientific Corporation | — |
| Active Not Recruiting | ADVENT Post Approval Study NCT06431815 | Boston Scientific Corporation | — |
| Active Not Recruiting | FIH of PFBalloon for PVI NCT07320976 | The Third People's Hospital of Chengdu | N/A |
| Recruiting | POLARx Post Approval Study (POLARx PAS) NCT06170606 | Boston Scientific Corporation | N/A |
| Recruiting | The Impact of Expandable Cryoballoon on Autonomic Control of the Heart NCT06053606 | Wroclaw Medical University | N/A |
| Not Yet Recruiting | Accelerated Pacing in Patients Undergoing Pace-and-ablate Strategy With LBBAP: a Randomized Controlled Pilot T NCT06377046 | Maastricht University Medical Center | N/A |
| Completed | Feasibility Study on the FARAVIEW Technology NCT06175234 | Boston Scientific Corporation | N/A |
| Completed | VOLT-AF IDE Clinical Study NCT06223789 | Abbott Medical Devices | N/A |
| Recruiting | The Long-term Safety and Effectiveness Evaluation of the QDOT MICRO System Use in Conjunction With VISITAG SUR NCT06324201 | Heart Rhythm Clinical and Research Solutions, LLC | — |
| Not Yet Recruiting | Role of Eplerenone in Reducing Recurrence of Atrial Fibrillation in Patient With Structural Heart Disease NCT06168994 | Assiut University | Phase 4 |
| Recruiting | ULTRA-HFIB-Redo: Ultrasound-based Renal Sympathetic Denervation vs Control in Redo Ablation Patients NCT05988411 | Vivek Reddy | N/A |
| Recruiting | Pulmonary Vein Isolation Strategy of Very High Power Short Duration in Patients With Paroxysmal Atrial Fibrill NCT05996159 | Seoul National University Hospital | N/A |
| Withdrawn | AcQBlate Force Sensing Ablation System US IDE Study for Atrial Fibrillation NCT04904354 | Acutus Medical | N/A |
| Recruiting | VOLT CE Mark Study NCT06106594 | Abbott Medical Devices | N/A |
| Active Not Recruiting | Treatment of PAF With the Synaptic System NCT05905835 | Synaptic Medical Corporation | N/A |
| Completed | A Study of Intracardiac Ultrasound With the NUVISION NAV Ultrasound Catheter NCT05970120 | Biosense Webster, Inc. | N/A |
| Completed | InsightPFA Trial of the LotosPFA Catheter NCT06014996 | Insight Medtech Co., Ltd. | N/A |
| Active Not Recruiting | Safety and Effectiveness of the Globe® Pulsed Field System for Treating Patients With Symptomatic Paroxysmal o NCT05462145 | Kardium Inc. | N/A |
| Completed | A RWS of the FARAPULSE in A Chinese Population With PAF NCT05493852 | Boston Scientific Corporation | — |
| Recruiting | BEAT AF - Braking Ectopic Atrial Trends In Atrial Fibrillation NCT05872776 | Ziv HealthCare Ltd. | N/A |
| Active Not Recruiting | A Study of the Acceptability and Performance of Wearables for Atrial Fibrillation Screening in Older Adults NCT04715555 | University of Cambridge | — |
| Withdrawn | Inflammatory and Endothelial Function Response, and Arrhythmia Recurrence Following Catheter Ablation for Atri NCT04269785 | Karan Saraf | N/A |
| Completed | Efficacy and Safety Evaluation of Refralon®, Concentrate for Solution for Intravenous Injection in Patients Wi NCT05773170 | R-Pharm | — |
| Completed | Safety-and-effectiveness Clinical Evaluation of Nanosecond-pulse Ablation for Atrial Fibrillation NCT06039722 | Shenzhen Pulsecare Medical Technology Co., Ltd. | N/A |
| Unknown | Combined Study of ATrial Strain and Voltage by High Density Mapping in Young Patients With Atrial Fibrillation NCT05565183 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | 3-Dimensional Mapping System: The PULSTAR Study NCT05618340 | Shanghai Shangyang Medical Technology Co., Ltd. | N/A |
| Active Not Recruiting | SINGLE SHOT CHAMPION NCT05534581 | Insel Gruppe AG, University Hospital Bern | Phase 4 |
| Recruiting | Biomarker-Guided Optimization of Transcutaneous Vagal Stimulation for Atrial (BiG tVNS-AF) NCT05172765 | University of Oklahoma | N/A |
| Completed | POLARx™ Cardiac Cryoablation System Post Market Clinical Study (POLAR SMART) NCT05282823 | Boston Scientific Corporation | — |
| Completed | A Study Assessing Arrhythmia Mapping With a Globe-Shaped, High-Density, Multi-Electrode Mapping Catheter NCT05373862 | Biosense Webster, Inc. | N/A |
| Completed | Clinical Performance of the AFGen1 Device Over a 7-day Period NCT05295056 | TriVirum, Inc. | — |
| Recruiting | STOP AF First Post-Approval Study NCT05227053 | Medtronic Cardiac Ablation Solutions | — |
| Terminated | Flecainide Acetate Inhalation Solution for Cardioversion of Recent-Onset, Symptomatic Atrial Fibrillation NCT05039359 | InCarda Therapeutics, Inc. | Phase 3 |
| Recruiting | Smartwatch and External Holter Monitoring to Detect Atrial Fibrillation in Patients With Cryptogenic Stroke NCT05565781 | Hospital Universitari Vall d'Hebron Research Institute | N/A |
| Terminated | MultiPulse Therapy (MPT) for AF (US) NCT05055921 | Cardialen, Inc. | N/A |
| Terminated | DIAMOND AF Post-Approval Study NCT05230524 | Medtronic Cardiac Ablation Solutions | — |
| Recruiting | Acute Responses to Exercise in Females and Males With Symptomatic Atrial Fibrillation NCT05085860 | Ottawa Heart Institute Research Corporation | N/A |
| Completed | High-Power, Short-Duration Ablation in Treatment of Patients With Atrial Fibrillation NCT06415149 | People's Friendship University of Russia | N/A |
| Unknown | Real-world Experience of Catheter Ablation Using Novel Ablation Technologies for the Treatment of Atrial Fibri NCT05006456 | Beijing Anzhen Hospital | — |
| Completed | The FARAPULSE FARA-Freedom Trial NCT05072964 | Boston Scientific Corporation | N/A |
| Completed | Evaluation of the Safety and Efficacy of the CardioPulseTM PuLsed fiEld Ablation SystEm in Patients With Parox NCT05114954 | Hangzhou Dinova EP Technology Co., Ltd | N/A |
| Recruiting | Computed Tomogram Myocardial Thickness Map Guided pulmOnary Vein iSolaTion vs. Empirical Pulmonary Vein Isolat NCT03912324 | Yonsei University | N/A |
| Completed | Automated Assessment of PVI Using a Novel EP Recording System NCT05043883 | CathVision ApS | N/A |
| Terminated | iCLAS™ Cryoablation System Post-Market Clinical Follow-up (PMCF) Study NCT05416086 | Adagio Medical | N/A |
| Unknown | Renal Denervation and pUlmonary Vein isolAtion With cryoabLation on Patients With Atrial Fibrillation and hypE NCT05024630 | Shanghai 10th People's Hospital | N/A |
| Completed | A Study Assessing Arrhythmia Mapping With the Multi-Electrode OPTRELL™ Mapping Catheter NCT04983797 | Biosense Webster, Inc. | N/A |
| Unknown | The Effect and Safety of Pulsed Field Ablation (PFA) in Patients With Paroxysmal Atrial Fibrillation (PAF) NCT05400928 | Tongji Hospital | N/A |
| Completed | Electrical Coupling Information From The RHYTHMIA HDx Mapping System and DIRECTSENSE Technology In The Treatme NCT04740801 | Boston Scientific Corporation | N/A |
| Completed | Baroreflex Sensitivity in Patients Undergoing Ablation of Atrial Fibrillation NCT04503122 | Poitiers University Hospital | — |
| Unknown | HIgh Power Short Duration Radiofrequency Ablation or Cryoballoon Ablation for Paroxysmal Atrial Fibrillation NCT04855890 | Universitätsklinikum Köln | N/A |
| Unknown | The RODEO Micro Mapping Catheter in Cryoablation Procedures NCT04845750 | afreeze GmbH | N/A |
| Completed | Clinical Evaluation of the StablePoint Catheter and Force Sensing System for Paroxysmal Atrial Fibrillation NCT04580914 | Boston Scientific Corporation | N/A |
| Active Not Recruiting | Comparison of PolarX and the Arctic Front Cryoballoons for PVI in Patients With Symptomatic Paroxysmal AF NCT04704986 | Insel Gruppe AG, University Hospital Bern | Phase 4 |
| Completed | The FARAPULSE ADVENT PIVOTAL Trial PFA System vs SOC Ablation for Paroxysmal Atrial Fibrillation NCT04612244 | Boston Scientific Corporation | N/A |
| Withdrawn | Boston Scientific's Single Shot LUMINIZE RF Balloon Catheter in the Treatment of Symptomatic, Drug Refractory NCT03852420 | Boston Scientific Corporation | N/A |
| Recruiting | Atrial Anomalies Predict Silent Atrial Fibrillation Detected by Implantable Cardiac Monitor in Cryptogenic Str NCT06542770 | Parc de Salut Mar | N/A |
| Unknown | Added Value of SVC Isolation in Patients With Pulmonary Vein Reconnection Undergoing Repeat Ablation for Recur NCT04602169 | AZ Sint-Jan AV | N/A |
| Completed | Determine AF Burden With PPG Trial - Detection and Quantification of Episodes of Atrial Fibrillation NCT04563572 | University Hospital, Basel, Switzerland | N/A |
| Unknown | Added Value of Vein of Marshal Ethanol Infusion Compared to Superior Vena Cava Isolation Alone in Patients Und NCT04529785 | AZ Sint-Jan AV | N/A |
| Unknown | Balloon Cryoablation Without Contrast NCT04344743 | Medicover Hospital | N/A |
| Completed | RHYTHMIA vs CARTO in Redo Ablation Procedures for Atrial Fibrillation NCT04835844 | The Cleveland Clinic | — |
| Completed | A Single Arm Pilot Study of Pulsed Field Ablation in the Treatment of Paroxysmal Atrial Fibrillation NCT04474054 | Boston Scientific Corporation | N/A |
| Completed | TactiFlex Paroxysmal Atrial Fibrillation IDE Trial NCT04356040 | Abbott Medical Devices | N/A |
| Completed | Boston Scientific's Cryoballoon in the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation NCT04133168 | Boston Scientific Corporation | N/A |
| Completed | Quality of Life Influencing Factors NCT05974098 | Peking University People's Hospital | — |
| Withdrawn | Ultrasensitive Electroanatomic Mapping to Adjudicate Endpoints for Ablation In Paroxysmal AF Patients Using Cr NCT04109053 | BayCare Health System | — |
| Completed | PEFCATII Expanded Safety and Feasibility Study of the FARAPULSE Endocardial Multi Ablation System to Treat Par NCT04170608 | Boston Scientific Corporation | N/A |
| Completed | HD Mapping of Atrial Fibrillation in Asia Pacific NCT04022954 | Abbott Medical Devices | — |
| Completed | High-Density (HD) Wave Mapping in Subjects With Atrial Fibrillation as a Predictor of Recurrence After a Singl NCT03882021 | Abbott Medical Devices | N/A |
| Completed | Reducing Recurrence of Symptomatic Atrial Fibrillation After Catheter Ablation by App-based Mental Training NCT04067427 | Helios Health Institute GmbH | N/A |
| Active Not Recruiting | THERMOCOOL SMARTTOUCH®SF Catheters With Ablation Index Study NCT03963349 | Biosense Webster, Inc. | — |
| Completed | LSI (Lesion Index) Workflow Observational Study NCT03906461 | Abbott Medical Devices | — |
| Unknown | First-in-Patient Study for Sing le Dose of M201-A Hydrochloride Injection in Japanese Patients With Paroxysmal NCT04609059 | Kitasato University | Phase 2 |
| Completed | High Power Short Duration Ablation Compared to Moderate Power Long Duration Ablation for Pulmonary Vein Isolat NCT05959798 | Deutsches Herzzentrum Muenchen | — |
| Unknown | Cryoballoon Pulmonary Vein Isolation vs. Radiofrequency Pulmonary Vein Isolation With Additional Right Atrial NCT03920917 | Yonsei University | N/A |
| Completed | Prospective Evaluation of Open Irrigated Ablation Catheters With High Resolution Mapping to Treat Paroxysmal A NCT03729830 | Boston Scientific Corporation | — |
| Completed | Evaluation of QDOT MICRO™ Catheter for Pulmonary Vein Isolation in Subjects With Paroxysmal Atrial Fibrillatio NCT03775512 | Biosense Webster, Inc. | N/A |
| Unknown | Compared With 2 Different Ablation Strategies Clinical Outcome for Treating Patients With Paroxysmal Atrial Fi NCT03190395 | Zhujiang Hospital | N/A |
| Unknown | Treatment Success With the CoolLoop Cryoablation System NCT03818724 | afreeze GmbH | — |
| Completed | Individualized Approach vs. Fixed Approach NCT03747263 | University of Luebeck | N/A |
| Completed | A Safety and Feasibility Study of the FARAPULSE Endocardial Ablation System to Treat Paroxysmal Atrial Fibrill NCT03714178 | Boston Scientific Corporation | N/A |
| Completed | Evaluation of VISITAG SURPOINT™ Module With External Processing Unit (EPU) NCT03624881 | Biosense Webster, Inc. | Phase 4 |
| Recruiting | Clinical Usefulness of Virtual Ablation Guided Catheter Ablation of Atrial Fibrillation: Virtual Rotor Mapping NCT02558699 | Yonsei University | N/A |
| Active Not Recruiting | Meditation and Education That is Nurse Delivered for Symptom Management in Paroxysmal Atrial Fibrillation (PAF NCT03834844 | Stanford University | N/A |
| Completed | AF Septal Pacing (Clinical Investigation Plan) NCT03242941 | Medtronic BRC | N/A |
| Completed | Additional Low Voltage Area Ablation in Older Patients With Paroxysmal Atrial Fibrillation NCT03462628 | The First Affiliated Hospital with Nanjing Medical University | N/A |
| Terminated | Model Based Fast Anatomical Mapping NCT03349476 | Vivek Reddy | N/A |
| Completed | Clinical Study for Safety and Acute Performance Evaluation of the THERMOCOOL SMARTTOUCH® SF-5D System Used Wit NCT03459196 | Biosense Webster, Inc. | N/A |
| Completed | Multi-electrode Radiofrequency Balloon Catheter Use for the Isolation of the Pulmonary Veins. NCT03437733 | Biosense Webster, Inc. | N/A |
| Completed | SMART Program for Paroxysmal Atrial Fibrillation NCT03450993 | Massachusetts General Hospital | N/A |
| Unknown | Atrial Electromechanical Function in Endurance Athletes With and Without Atrial Fibrillation NCT03305744 | University of Toronto | — |
| Unknown | Clinical Investigation of the VytronUS Ablation System for Treatment of Symptomatic Drug-refractory Paroxysmal NCT03513029 | VytronUS, Inc. | N/A |
| Completed | IMPULSE: A Safety and Feasibility Study of the IOWA Approach Endocardial Ablation System to Treat Atrial Fibri NCT03700385 | Boston Scientific Corporation | N/A |
| Completed | FIRE AND ICE Re-Ablations (Retrospective Data Collection) NCT03314753 | Medtronic Cardiac Ablation Solutions | — |
| Completed | Electrical Coupling Information From The Rhythmia HDx System And DirectSense Technology In Subjects With Parox NCT03232645 | Boston Scientific Corporation | N/A |
| Recruiting | Real-world Experience of Catheter Ablation for the Treatment of Paroxysmal and Persistent Atrial Fibrillation NCT04088071 | Heart Rhythm Clinical and Research Solutions, LLC | — |
| Completed | IMPACT: A Safety and Feasibility Study of the IOWA Approach Cardiac Ablation System NCT03700372 | Boston Scientific Corporation | — |
| Completed | TactiSense IDE Trial of TactiCath SE for Paroxysmal Atrial Fibrillation NCT03354663 | Abbott Medical Devices | N/A |
| Active Not Recruiting | Ectopy Triggering Ganglionated Plexus Ablation to Prevent Atrial Fibrillation NCT02487654 | Imperial College London | N/A |
| Completed | DiamondTemp™ Ablation System for the Treatment of Paroxysmal Atrial Fibrillation NCT03334630 | Medtronic Cardiac Ablation Solutions | N/A |
| Unknown | Influence of an Innovative Telemetric Smartphone Application on Re-hospitalization NCT03268707 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Active Not Recruiting | Adjunctive Ganglionated Plexus Ablation in Redo-Pulmonary Vein Isolation NCT03535818 | Imperial College London | N/A |
| Unknown | Safety and Feasibility of Electrical Isolation of the Superior Vena Cava for Paroxysmal Atrial Fibrillation NCT03190096 | Ettore Sansavini Health Science Foundation | — |
| Completed | CardioFocus vs. Contact Force Guided Pulmonary Vein Isolation in Paroxysmal Atrial Fibrillation NCT03056222 | I-Med-Pro GmbH | N/A |
| Completed | Evaluation of Ablation Index and VISITAG™ (ABI-173) NCT03062046 | Biosense Webster, Inc. | N/A |
| Completed | Addition of Six Short Lines on Pulmonary Vein Isolation NCT02637453 | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | N/A |
| Completed | Predictive Factors to Effectively Terminate Paroxysmal Atrial Fibrillation by Blocking Atrial Selective Ionic NCT03005366 | David Filgueiras-Rama | Phase 4 |
| Completed | Randomized Evaluation of Redo Ablation Procedures of Atrial Fibrillation With FIRM Guided Procedures NCT02799043 | Abbott Medical Devices | N/A |
| Completed | CAPA-VU Trial Catheter Ablation in Paroxymal Atrial Fibrillation Based on UNIVU NCT03198858 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Terminated | FIRM Ablation Versus Pulmonary Vein Isolation for the Treatment of Paroxysmal Atrial Fibrillation (PAF) NCT02703454 | Abbott Medical Devices | N/A |
| Completed | Effect of Treatment of Sleep Apnea in Patients With Paroxysmal Atrial Fibrillation NCT02727192 | Oslo University Hospital | N/A |
| Completed | Clinical Investigation of the VytronUS Ablation System for Treatment of Paroxysmal Atrial Fibrillation NCT03639597 | VytronUS, Inc. | N/A |
| Completed | ACT DiamondTemp TempeRAture-Controlled and Contact Sensing RF Ablation Clinical Trial for Atrial Fibrillation NCT02821351 | Medtronic Cardiac Ablation Solutions | N/A |
| Withdrawn | PVI Using Cryoablation Alone in Paroxysmal AF Patients Converted From Persistent AF With Dofetilide NCT01877486 | University of Rochester | — |
| Completed | Cryoballoon Pulmonary Vein Isolation Including Associated Esophageal Effects NCT02998866 | Baylor Research Institute | N/A |
| Unknown | Study of Statin for Reduction of Postoperative Paroxysmal Atrial Fibrillation NCT02502110 | The Third Xiangya Hospital of Central South University | Phase 4 |
| Completed | Comparison of Single Groin and Single Trans-septal Puncture and Conventional Bilateral Groin Puncture and Doub NCT02438176 | Yonsei University | N/A |
| Unknown | Assessment of Reconstruction and Inverse Reconstruction in Right Atrium by Multimodal Echocardiographic Techni NCT02838914 | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | N/A |
| Completed | TactiCath® Contact Force Ablation Catheter Study for Atrial Fibrillation Post Approval Study NCT02310100 | Abbott Medical Devices | N/A |
| Terminated | Reduction of AF Ablation Induced Thrombo-Embolic Incidence Pilot Study NCT02275260 | Biotronik SE & Co. KG | N/A |
| Completed | The OneFreeze Study NCT02217254 | University of California, San Francisco | N/A |
| Completed | Cryoballoon vs. Irrigated Radiofrequency Catheter Ablation: Double Short vs. Standard Exposure Duration NCT01913522 | University of British Columbia | N/A |
| Completed | Paroxysmal Atrial Fibrillation in Patients With Acute Ischemic Stroke NCT02610803 | Odense University Hospital | — |
| Terminated | A Blinded Study to Evaluate Effect on Atrial Fibrillation Burden in Patients With Paroxysmal Atrial Fibrillati NCT02156076 | Bristol-Myers Squibb | Phase 2 |
| Completed | A Feasibility Study to Evaluate the Effect of Concomitant Renal Denervation and Cardiac Ablation on AF Recurre NCT01907828 | Abbott Medical Devices | N/A |
| Completed | Treatment of Atrial Fibrillation in Patients by Pulmonary Vein Isolation in Combination With Renal Denervation NCT02115100 | Diagram B.V. | N/A |
| Unknown | Effects of Mediyoga in Patients With Paroxysmal Atrial Fibrillation-MYPAF NCT02223156 | Danderyd Hospital | — |
| Completed | Efficacy, Safety and Efficiency of the nMARQ Pulmonary Vein Isolation System in Paroxysmal Atrial Fibrillation NCT02268539 | Mid and South Essex NHS Foundation Trust | N/A |
| Completed | Increasing Atrial Base Rate Pacing to Reduce Atrial Fibrillation NCT02317068 | Urmia University of Medical Sciences | Phase 3 |
| Completed | Cryoballoon PVI With PWI Versus PVI Alone In Patients With PAF NCT05296824 | Sacramento EP Research | — |
| Completed | Pilot Study Evaluating the Toray Satake Balloon Thermal Ablation System for Treatment of Paroxysmal Atrial Fib NCT01997736 | Toray Industries (America), Inc. | N/A |
| Terminated | Focal Impulse and Rotor Modulation Ablation Trial for Treatment of Paroxysmal Atrial Fibrillation (FIRMAT-PAF) NCT01925885 | Indiana University | N/A |
| Withdrawn | Testing the Accuracy of a Personal Heart Rhythm Monitor to Detect Prolonged Paroxysmal Atrial Fibrillation NCT01917981 | University of Surrey | Phase 3 |
| Terminated | Use of the Hansen Medical System in Patients With Paroxysmal Atrial Fibrillation NCT01122173 | Hansen Medical | N/A |
| Completed | Evaluating the Efficacy and Feasibility of a Novel Wireless ECG Recording System in Monitoring Patients After NCT01912911 | The Cleveland Clinic | — |
| Unknown | Pulmonary Vein Isolation Versus Botulinum Toxin Injection Plus Pulmonary Vein Isolation in Patients With Atria NCT02002923 | Meshalkin Research Institute of Pathology of Circulation | Phase 2 |
| Unknown | Botulinum Toxin Injection Prevent Paroxysmal Atrial Fibrillation NCT02002988 | Meshalkin Research Institute of Pathology of Circulation | Phase 1 |
| Completed | A Study of the Safety and Efficacy of the VytronUS Low-Intensity Collimated Ultrasound Ablation System NCT01900678 | VytronUS, Inc. | N/A |
| Unknown | PV Reconnection After PVAI at Different Power Settings and Adenosine Provocation NCT01672346 | Texas Cardiac Arrhythmia Research Foundation | Phase 3 |
| Completed | Using a Personal Heart Rhythm Monitor to Diagnose Paroxsymal Atrial Fibrillation in the Community NCT01867060 | University of Surrey | Phase 3 |
| Terminated | Oral Anticoagulation Therapy Pilot Study NCT01959425 | Biosense Webster, Inc. | Phase 4 |
| Terminated | Surgical Pulmonary Vein Isolation Efficiency Study NCT01791218 | Kuopio University Hospital | N/A |
| Completed | Antazoline in Rapid Cardioversion of Paroxysmal Atrial Fibrillation NCT01527279 | National Institute of Cardiology, Warsaw, Poland | Phase 4 |
| Completed | Antiarrhythmic and Symptomatic Effect of ISIS CRP Rx Targeting CRP in Paroxysmal Atrial Fibrillation NCT01710852 | Ionis Pharmaceuticals, Inc. | Phase 2 |
| Completed | Atrial Fibrillation Force Contact Ablation Study NCT01693107 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | — |
| Completed | Botulinum Toxin Injection in Epicardial Fat Pads To Treat Atrial Fibrillation After Cardiac Surgery NCT01842529 | Meshalkin Research Institute of Pathology of Circulation | Phase 2 |
| Completed | Durability of Pulmonary Vein Isolation Following Cryoablation for Treatment of Paroxysmal Atrial Fibrillation NCT01645917 | Medtronic Cardiac Rhythm and Heart Failure | Phase 4 |
| Completed | Effect of Cavotricuspid Isthmus Ablation in Patients Without History of Typical Flutter During Ablation NCT02031705 | Yong Seog Oh | N/A |
| Completed | Effectiveness Study of Circumferential vs. Segmental Ablation in Paroxysmal Atrial Fibrillation NCT02106663 | University of California, San Diego | N/A |
| Unknown | Efficacy of Pilsicainide After Radiofrequency Ablation of Paroxysmal Atrial Fibrillation NCT01775891 | Korea University | N/A |
| Unknown | Left Atrial Ablation of Paroxysmal Atrial Fibrillation With Implantable Loop Recorder Follow Up Study: The LAA NCT01504451 | Neil Sulke | Phase 4 |
| Completed | Adenosine vs AF Termination for Paroxysmal AF Ablation NCT02238392 | Johannes Gutenberg University Mainz | N/A |
| Completed | HeartLight Ablation in Patients With Paroxysmal Atrial Fibrillation (PAF) NCT01456000 | CardioFocus | Phase 3 |
| Unknown | Ablation as First Line Treatment in Paroxysmal Atrial Fibrillation NCT01466842 | Maastricht University Medical Center | N/A |
| Terminated | Ascending Dose Study of OPC-108459 Intravenous Infusions in Patients With Paroxysmal and Persistent Atrial Fib NCT01483183 | Otsuka Pharmaceutical Development & Commercialization, Inc. | Phase 1 |
| Completed | GENESIS Feasibility Study of the BARD Over-the-Wire Mesh Ablation System for the Treatment of Paroxysmal Atria NCT01430949 | C. R. Bard | Phase 2 |
| Completed | Thoracoscopic Versus Endocardial Ablation in Patient With Paroxysmal AF After Failed Initial Endocardial Ablat NCT01794416 | Meshalkin Research Institute of Pathology of Circulation | Phase 2 |
| Terminated | Atrial Fibrillation: Ablation or Surgical Treatment II: FAST II NCT01336075 | Aalborg University Hospital | N/A |
| Completed | REVOLUTION (WFCC-133) - Treatment of Paroxysmal Atrial Fibrillation NCT01353586 | Biosense Webster, Inc. | Phase 2 |
| Completed | TactiCath Contact Force Ablation Catheter Study for Atrial Fibrillation NCT01278953 | Abbott Medical Devices | N/A |
| Completed | Safety and Efficacy of Cryoballoon Ablation of Atrial Fibrillation as First-line Therapy NCT01920295 | Yuksek Ihtisas Hospital | N/A |
| Completed | TactiCath® Prospective Effectiveness Pilot Study NCT02131337 | Abbott Medical Devices | N/A |
| Unknown | Contact Force Sensing and Pulmonary Vein Isolation NCT01630031 | Clinique Pasteur | — |
| Unknown | Repeat Ablation Procedure in Patients With Relapse of Atrial Fibrillation NCT01229306 | Deutsches Herzzentrum Muenchen | N/A |
| Terminated | Optimal Sensing in Atrial Tachyarrhythmia's Study NCT01074749 | Abbott Medical Devices | N/A |
| Completed | Clinical Evaluation of Therapy™ Cool Flex Ablation Catheter for the Treatment of Paroxysmal Atrial Fibrillatio NCT01185613 | Abbott Medical Devices | Phase 2 |
| Unknown | Left Atrial Ablation With Permanent Pacemaker or ImplanTable Loop Recorder Follow-UP NCT01095770 | Eastbourne General Hospital | N/A |
| Terminated | Safety and Efficacy Study of the Combined Ablation Procedure to Treat Paroxysmal Atrial Fibrillation NCT01103674 | nContact Surgical Inc. | N/A |
| Unknown | Dronedarone in Pacemakers Patients With Paroxysmal Atrial Fibrillation NCT01070667 | Eastbourne General Hospital | Phase 4 |
| Completed | Irrigated Ablation System Evaluation for Atrial Fibrillation (AF) NCT01056328 | Abbott Medical Devices | N/A |
| Completed | ADenosine Following Pulmonary Vein Isolation to Target Dormant Conduction Elimination: the ADVICE Trial NCT01058980 | Montreal Heart Institute | Phase 4 |
| Terminated | Post-Market Randomized Trial: Endoscopically- Guided Ablation vs. Radiofrequency Ablation NCT01057394 | CardioFocus | Phase 4 |
| Completed | Effects of Mediyoga in Patients With Paroxysmal Atrial Fibrillation NCT01789372 | Danderyd Hospital | — |
| Completed | Randomized Trial of Segmental Versus Circumferential Antral Ablation in Paroxysmal Atrial Fibrillation NCT01260220 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Terminated | Guided Radiofrequency Ablation Using the CARTO® 3 and NavX™ Systems for the Treatment of Paroxysmal Atrial Fib NCT01036724 | Biosense Webster, Inc. | — |
| Completed | Unexcitability Along the Ablation as an Endpoint for Atrial Fibrillation Ablation NCT01724437 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Completed | Cryoballoon Ablation of Pulmonary Veins After Failed RF Ablation in Patients With Paroxysmal AF NCT01611701 | Meshalkin Research Institute of Pathology of Circulation | Phase 3 |
| Completed | NAVISTAR® THERMOCOOL® Catheter Post Approval Registry NCT00964392 | Biosense Webster, Inc. | Phase 4 |
| Completed | Clinical Study of the CardioFocus Endoscopic Ablation System - Adaptive Contact (EAS-AC) for the Treatment of NCT00971204 | CardioFocus | Phase 2 |
| Completed | Clinical Study of the CardioFocus Endoscopic Ablation System for the Treatment of Symptomatic AF NCT00958165 | CardioFocus | Phase 3 |
| Terminated | Study of HD Mesh Ablation System for Treatment of Paroxysmal Atrial Fibrillation NCT00741611 | C. R. Bard | Phase 3 |
| Unknown | Primary Anatomical Versus Primary Electrophysiological Approach in Circumferential Pulmonary Vein Ablation NCT00556595 | University Hospital, Bonn | N/A |
| Completed | A Comparison of the Drug Therapy Versus Re-Ablation NCT01709682 | Meshalkin Research Institute of Pathology of Circulation | Phase 2 |
| Completed | Ablation of the Pulmonary Veins for Paroxysmal Afib NCT00744874 | Medtronic Cardiac Rhythm and Heart Failure | Phase 4 |
| Completed | A Clinical Study of the Arctic Front Cryoablation Balloon for the Treatment of Paroxysmal Atrial Fibrillation NCT00523978 | Medtronic Cardiac Rhythm and Heart Failure | Phase 3 |
| Completed | Navi-Star Thermo-Cool Catheter For Ablation of Atrial Fibrillation NCT00584415 | University of Oklahoma | N/A |
| Completed | A Comparison of Antiarrhythmic Drug Therapy and Radio Frequency Catheter Ablation in Patients With Paroxysmal NCT00540787 | Biosense Webster, Inc. | Phase 4 |
| Unknown | Statin and PAF in Patients With Pacemaker NCT00201552 | National Taiwan University Hospital | N/A |