| Not Yet Recruiting | Antibiotic Device for Osteomyelitis of the Extremities Pivotal Trial - Genex With Gentamicin. NCT07270380 | Biocomposites Ltd | N/A |
| Not Yet Recruiting | The ACHILLS Trial; Application of Cerament in Heel Infection for Lower Limb Salvage NCT07057817 | Royal College of Surgeons, Ireland | N/A |
| Recruiting | A Randomized Controlled Phase II Trial of STIMULAN VG vs Standard of Care (SoC) for the Treatment of Osteomyel NCT06283979 | Biocomposites Ltd | Phase 2 |
| Recruiting | CERAMENT G as Part of the Surgical Treatment of Osteomyelitis in a Single-Stage Procedure NCT06555848 | BONESUPPORT AB | — |
| Recruiting | Monotherapy vs Combination Therapy for Bone Infections Caused by Pseudomonas Aeruginosa NCT07056881 | Centre Hospitalier de Saint-Denis | — |
| Active Not Recruiting | Retention and Re-Engagement in Treatment for Addiction Following Serious Injection Related Infections (RETAIN) NCT06489535 | Boston Medical Center | N/A |
| Not Yet Recruiting | Surgical Treatment of Osteoarticular Infections Using Bioactive Bone Substitute NCT06402292 | Federal University of São Paulo | N/A |
| Active Not Recruiting | Quasi-Randomized Evaluation of the UCLA Next Day Clinic (NDC) NCT06526884 | University of California, Los Angeles | N/A |
| Unknown | Effect of Pulsed Electromagnetic Field Stimulation on Localized Pediatric Osteomyelitis NCT06084754 | Cairo University | N/A |
| Unknown | Don't Treat Ghosts Anti-MRSA Antibiotics in Osteomyelitis Without Identified MRSA NCT06096012 | Methodist Health System | — |
| Unknown | RETR(Osteomyelitis) NCT04936958 | Hospices Civils de Lyon | — |
| Recruiting | Treatment of Osteomyelitis-associated Pressure Ulcers by Surgical Flaps and Anti-bacterial Agents NCT05713149 | Institut de Sante Parasport Connecte Synergies | — |
| Unknown | Diabetic Foot Osteomyelitis Treatment Using Gentamicin-loaded Calcium Sulfate-hydroxyapatite Biocomposite NCT05316298 | University Medical Center Groningen | — |
| Terminated | Bacteriophage Therapy in Patients With Diabetic Foot Osteomyelitis NCT05177107 | Adaptive Phage Therapeutics, Inc. | Phase 2 |
| Recruiting | BonE and Joint Infections - Simplifying Treatment in Children Trial NCT04538053 | Murdoch Childrens Research Institute | Phase 4 |
| Unknown | Acute Non-severe Osteomyelitis in Children - Outpatient Management Strategy With Oral Antibiotic Therapy Compa NCT04554108 | Assistance Publique - Hôpitaux de Paris | N/A |
| Unknown | Treatment of Fracture Related Infection in Latin America. NCT05467644 | Manoel Victorino Hospital | — |
| Completed | Oral-only Antibiotics for Bone and Joint Infections in Children NCT04563325 | Rigshospitalet, Denmark | Phase 4 |
| Unknown | Development of Risk Score Model and Decision Tree Algorithm for Predicting Infections With CRKp in Colonized P NCT04229511 | SCARE (Study group for carbapenem resistance) | — |
| Completed | Next-Generation Sequencing for Pathogen Detection and Quantification in Children With Musculoskeletal Infectio NCT03846804 | Indiana University | N/A |
| Unknown | Ceftriaxone as Home IV for Staph Infections NCT04141787 | Vancouver Island Health Authority | Phase 4 |
| Completed | Cefadroxil and Cephalexin Drug Levels and Dosing in Pediatric Musculoskeletal Infections NCT03802552 | University of Colorado, Denver | Phase 1 |
| Completed | Short or Long Antibiotic Regimes in Orthopaedics NCT03806166 | Oxford University Hospitals NHS Trust | N/A |
| Completed | Evaluation of Outcomes of Surgical Treatment for Nonspecific Infectious Spondylodiscitis Via Posterior Approac NCT07349602 | Federal State Budgetary Organization, Federal Center for Traumatology, Orthopedics and Arthroplasty | N/A |
| Recruiting | Additional Hyperbaric Oxygen After Lower Extremity Amputation NCT03594344 | Oslo University Hospital | N/A |
| Completed | Dalbavancin For The Treatment of Gram Positive Osteoarticular Infections NCT03426761 | Infectious Diseases Physicians, Inc. | Phase 4 |
| Completed | Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics NCT03012529 | VA Office of Research and Development | Phase 4 |
| Terminated | Safety and Efficacy of Dalbavancin Versus Active Comparator in Adult Patients With Osteomyelitis NCT03091439 | Allergan | Phase 2 |
| Completed | Acinetobacter Baumannii-related Osteomyelitis: Clinical and Epidemiological Characterization NCT03559530 | University of Sao Paulo | — |
| Recruiting | Fosfomycin I.v. for Treatment of Severely Infected Patients NCT02979951 | Infectopharm Arzneimittel GmbH | — |
| Completed | Study on the Safety and Efficacy of Dalbavancin Versus Active Comparator in Adult Participants With Osteomyeli NCT02685033 | Durata Therapeutics Inc., an affiliate of Allergan plc | Phase 2 |
| Withdrawn | Dalbavancin vs Comparator in Pediatric Subjects With Acute Hematogenous Osteomyelitis NCT02344511 | Durata Therapeutics International BV (an Affiliate of Actavis, Inc.) | Phase 3 |
| Completed | Ceftaroline for Treatment of Hematogenously Acquired Staphylococcus Aureus Osteomyelitis in Children NCT02335905 | Baylor College of Medicine | Phase 1 / Phase 2 |
| Completed | Hematogenous Osteomyelitis in Childhood Can Relapse Dozens of Years in Adulthood NCT03898219 | Hospices Civils de Lyon | — |
| Completed | UT Southwestern Diabetic Foot Ulcers (DFU) and Osteomyelitis (DFO) Recruitment Database, Data and Tissue Repos NCT02463500 | University of Texas Southwestern Medical Center | — |
| Completed | Osteomyelitis: Procalcitonin to Diagnose and Monitor Osteomyelitis (PCT) NCT02308774 | University of Texas Southwestern Medical Center | — |
| Withdrawn | Investigation of the Use of Hyperspectral Imaging in Foot Surgery Patients NCT03787862 | University of Texas Southwestern Medical Center | — |
| Completed | Osteomyelitis: Procalcitonin to Diagnose and Monitor Osteomyelitis NCT02165579 | University of Texas Southwestern Medical Center | — |
| Unknown | CERAMENT™|G - Bone Healing and Re-infection Prophylaxis NCT02128256 | Dr. Olivier Borens | Phase 4 |
| Terminated | Efficacy of Oral Antibiotic Therapy Compared to Intravenous Antibiotic Therapy for Osteomyelitis NCT02168816 | Loyola University | Phase 2 |
| Terminated | Patients Response to Early Switch To Oral:Osteomyelitis Study NCT02099240 | Julio Ramirez | EARLY_Phase 1 |
| Completed | Ferumoxytol-enhanced Imaging of Osteomyelitis NCT05959590 | University of New Mexico | Phase 1 |
| Withdrawn | Ceftaroline in the Treatment of Bone and Joint Infections NCT02005068 | Orlando Health, Inc. | Phase 4 |
| Completed | PET-MRI in Diagnosing Patients With Cancer, Cardiac Diseases, or Neurologic Diseases NCT02084147 | Case Comprehensive Cancer Center | N/A |
| Completed | Denosumab Related Osteonecrossi of the Jaw : : an Emergent and Potentially Complex Bone and Joint Infection NCT03808285 | Hospices Civils de Lyon | — |
| Completed | Optimising Diagnosis and Antibiotic Prescribing for Acutely Ill Children in Primary Care NCT02024282 | KU Leuven | N/A |
| Completed | Risk Factors for Three Critical Stages of the Diabetic Foot Infections NCT02736253 | Ege University | — |
| Unknown | Clinical Effectiveness of S53P4 Bioactive Glass in Treatment of Long-bone Chronic Osteomyelitis NCT04945434 | Academisch Ziekenhuis Maastricht | N/A |
| Completed | Differentiation of Bone Sarcomas and Osteomyelitis With Ferumoxytol-Enhanced MRI NCT01336803 | Heike E Daldrup-Link | Phase 2 |
| Terminated | Diagnostic Tests to Help Determine Osteomyelitis NCT01612962 | Georgetown University | — |
| Completed | Drug Delivery Devices for Osteomyelitis NCT02968693 | Yulin Orthopedics Hospital of Chinese and Western Medicine | — |
| Unknown | Efficacy of Surgical Treatment of Osteomyelitis in Diabetic Foot Ulcers NCT01137903 | Universidad Complutense de Madrid | N/A |
| Completed | A Clinical Trial Testing the Efficacy of PDT in Preventing Amputation in Diabetic Patients NCT03380403 | Faculdade de Medicina do ABC | N/A |
| Completed | Comparative Effectiveness of Intravenous v. Oral Antibiotic Therapy for Serious Bacterial Infections NCT02311452 | Children's Hospital of Philadelphia | — |
| Completed | Procalcitonin Level and Kinetics in Children With Bacterial Infections NCT00714402 | Shaare Zedek Medical Center | — |
| Completed | The RAD-HOME Project: a Pilot Study of Domiciliary Teleradiology NCT01098916 | Azienda Ospedaliera San Giovanni Battista | N/A |
| Completed | Study of Daptomycin in Subjects Undergoing Surgery for Osteomyelitis Associated With an Infected Prosthetic Ca NCT00428844 | Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | Phase 2 |
| Completed | The Influence of Bisphosphonates in the Oral Cavity in Children NCT00402064 | Hadassah Medical Organization | — |
| Completed | Study Evaluating the Safety and Efficacy of a Once-daily Dose of Tigecycline vs Ertapenem in Diabetic Foot Inf NCT00366249 | Wyeth is now a wholly owned subsidiary of Pfizer | Phase 3 |
| Completed | Vancomycin Or Trimethoprim/Sulfamethoxazole for Methicillin-resistant Staphylococcus Aureus Osteomyelitis NCT00324922 | University of Washington | Phase 3 |