| Terminated | Pharmacologically-based Strategies for Opioid Substitution Therapy During Pregnancy NCT03831113 | Steve N. Caritis, MD | Phase 2 |
| Completed | Onsite Buprenorphine Treatment at Syringe Exchange Programs NCT03150173 | Montefiore Medical Center | Phase 2 |
| Completed | A Prospective Investigation of the Risks of Opioid Misuse, Abuse, and Addiction Among Patients Treated With Op NCT02751762 | Member Companies of the Opioid PMR Consortium | — |
| Unknown | The Effectiveness of Deep Brain Stimulation for Opioid Relapse Prevention NCT02440152 | Ruijin Hospital | Phase 2 / Phase 3 |
| Completed | Long-acting Naltrexone for Pre-release Prisoners NCT02867124 | Friends Research Institute, Inc. | Phase 3 |
| Completed | Pilot Study of Contingency Management for Smoking Cessation NCT03015597 | King's College London | N/A |
| Terminated | Discontinuation vs Continuation of Long-term Opioid Therapy in Suboptimal and Optimal Responders With Chronic NCT02741076 | Member Companies of the Opioid PMR Consortium | Phase 4 |
| Completed | Impact of Pregnancy on Buprenorphine Pharmacokinetics and Pharmacodynamics NCT02863601 | University of Pittsburgh | — |
| Completed | Using Artificial Intelligence To Monitor Medication Adherence in Opioid Replacement Therapy NCT02243670 | AiCure | N/A |
| Completed | Study to Evaluate the Exposures of Lofexidine and Its Major Metabolites in Subjects Seeking Buprenorphine Dose NCT02801357 | USWM, LLC (dba US WorldMeds) | Phase 1 |
| Completed | Impact of Different Educational Approaches on Post-operative Opiate Utilization After Elective Lower Extremity NCT02997644 | Brooke Army Medical Center | N/A |
| Completed | Immediate Postpartum Nexplanon Placement in Opioid Dependent Women NCT02657148 | University of Pittsburgh | — |
| Completed | On-site Evaluation of Substances Consumption on Opiate Maintenance NCT02345655 | University Hospital, Toulouse | N/A |
| Completed | Validation of PRISM-5-Op, Measure Of Addiction To Prescription Opioid Medication NCT02660619 | Member Companies of the Opioid PMR Consortium | — |
| Completed | Prevalence and Predictors of Prolonged Post-surgical Opioid Use: a Prospective Observational Cohort Study NCT02571400 | University of Notre Dame Australia | — |
| Completed | Acute and Short-term Effects of CBD on Cue-induced Craving in Drug-abstinent Heroin-dependent Humans NCT02539823 | Hurd,Yasmin, Ph.D. | Phase 2 |
| Completed | Study of Opioid Use After Lumbar and Cervical Spine Surgery NCT02674711 | Brooke Army Medical Center | N/A |
| Completed | An Observational Study to Develop Algorithms for Identifying Opioid Abuse and Addiction Based on Admin Claims NCT02667262 | Member Companies of the Opioid PMR Consortium | — |
| Completed | Study to Validate Coded Medical Terms Used to Identify Opioid-Related Overdose in Databases Used for PMR Study NCT02667197 | Member Companies of the Opioid PMR Consortium | — |
| Completed | A Quantitative Study to Assess the Construct Validity of the Prescription Opioid Misuse and Abuse Questionnair NCT02678507 | Member Companies of the Opioid PMR Consortium | — |
| Completed | Cross-Sectional Study to Define and Validate "Doctor/Pharmacy Shopping" as Outcomes Suggestive of Abuse and/or NCT02668549 | Member Companies of the Opioid PMR Consortium | — |
| Completed | A Qualitative Study to Assess the Content Validity of the Prescription Opioid Misuse and Abuse Questionnaire NCT02660606 | Member Companies of the Opioid PMR Consortium | — |
| Completed | Study of Treatment for Opioid Dependence and Anxiety Disorders NCT02252068 | Mclean Hospital | N/A |
| Completed | A Survey to Eval the Relation Between Doctor/Pharmacy Shopping and Outcomes Suggestive of Misuse, Abuse and/or NCT02667158 | Member Companies of the Opioid PMR Consortium | — |
| Completed | Study to Eval Relation Btw Doctor/Pharmacy Shopping & Outcomes of Misuse, Diversion, Abuse, Addiction by Med R NCT02667210 | Member Companies of the Opioid PMR Consortium | — |
| Completed | HIV, Buprenorphine, and the Criminal Justice System (STRIDE2) NCT03583138 | Yale University | — |
| Completed | The Comparison of Stress Response to Rapid Opioid Detoxification Applying Different Methods of Opioid Antagoni NCT02362256 | Vilnius University | N/A |
| Unknown | Effectiveness of a Hospital Addiction Service in Treating Opioid and Alcohol Addiction NCT01934751 | Women's College Hospital | N/A |
| Completed | Variation of COMT Val158Met Polymorphism Between COM-ON Patients and METHADOSE Patients NCT01570699 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Acute and Short-term Effects of Cannabidiol Admin on Cue-induced Craving in Drug-abstinent Heroin Dependent Hu NCT01605539 | Hurd,Yasmin, Ph.D. | Phase 2 |
| Completed | HIV, Buprenorphine, and the Criminal Justice System NCT01550341 | Yale University | N/A |
| Completed | Methadone Monitoring for Insights Into Adverse Events NCT01191242 | Intermountain Health Care, Inc. | — |
| Completed | Study to Test the Safety and Efficacy of Cannabidiol as a Treatment Intervention for Opioid Relapse NCT01311778 | Hurd,Yasmin, Ph.D. | Phase 1 |
| Completed | Intervention of HIV, Drug Use and the Criminal Justice System in Malaysia NCT02396979 | Yale University | Phase 4 |
| Unknown | Opiate Detoxification Using the Combined Hemoperfusion-hemodialysis NCT01021566 | First People's Hospital of Foshan | Phase 3 |
| Withdrawn | Comparison of Buprenorphine/Naloxone With Naltrexone in Opioid Dependent Adolescents NCT01015066 | State University of New York at Buffalo | Phase 4 |
| Completed | Buprenorphine and Methadone for Opioid Dependent Chronic Pain Patients NCT00879996 | State University of New York at Buffalo | Phase 4 |
| Completed | Safety Study of Intravenous 6β-Naltrexol (AIKO-150) in Opioid-Dependent Subjects NCT00829777 | California Pacific Medical Center Research Institute | Phase 1 |
| Completed | Models of Screening, Brief Intervention With a Facilitated Referral to Treatment (SBIRT) for Opioid Patients i NCT00913770 | Yale University | N/A |
| Completed | Examination of Cognitive Function in Patients Treated With Subutex NCT00687089 | BeerYaakov Mental Health Center | — |
| Completed | Treatment Study Using Depot Naltrexone (1/6) Philadelphia Coord/Data Mgmt Site NCT00781898 | University of Pennsylvania | Phase 2 / Phase 3 |
| Terminated | Buprenorphine as a Treatment in Opiate Dependent Pain Patients NCT00552578 | State University of New York at Buffalo | Phase 4 |
| Completed | Efficacy of Computer Delivered Community Reinforcement Approach (CRA) (Bup II) NCT00929253 | Virginia Polytechnic Institute and State University | N/A |
| Completed | Buprenorphine Maintenance for Opioid-Addicted Persons in Jail and Post-Release NCT00367302 | National Development and Research Institutes, Inc. | Phase 1 / Phase 2 |
| Completed | Lofexidine for Inpatient Opiate Detox NCT00235729 | US Department of Veterans Affairs | Phase 3 |
| Completed | Insomnia and Drug Relapse Risk NCT00253890 | Butler Hospital | Phase 3 |
| Completed | Integration of Buprenorphine Into HIV Clinical Settings - Primary Care Model (PCM) NCT00798538 | Yale University | Phase 4 |
| Completed | Naltrexone Implants vs. MMT Among Inmates in the Norwegian Correctional Services NCT00204243 | University of Oslo | Phase 2 |
| Completed | NAOMI: A Study to Compare Medically-prescribed Heroin With Oral Methadone in Chronic Opiate Addiction NCT00175357 | University of British Columbia | Phase 3 |
| Completed | Evaluation of DBT Compared to Drug Counseling for Opiate Addicts NCT00117741 | University of Washington | N/A |
| Completed | Real Time Assessment of Drug Craving, Use, and Abstinence During Outpatient: A Development and Feasibility Stu NCT00292136 | National Institute on Drug Abuse (NIDA) | — |
| Completed | Recovery Housing and Drug Abuse Treatment Outcome NCT03278496 | Johns Hopkins University | N/A |
| Unknown | Evaluation of Drug Utilization Patterns for Extended Release/Long Acting Opioids and Comparator Products NCT02925806 | ER/LA Opioid REMS Program Companies (RPC) | — |
| Unknown | Monitoring Patterns of Prescribing to Identify Changes in Access to ER/LA Opioid Analgesics NCT02920775 | ER/LA Opioid REMS Program Companies (RPC) | — |
| Unknown | Evaluation of Changes in Prescribing Behavior of ER/LA Opioid Prescribers NCT02920762 | ER/LA Opioid REMS Program Companies (RPC) | — |