| Not Yet Recruiting | An Extension Study to Assess the Long-term Safety of the Genio® System NCT05939141 | Nyxoah S.A. | — |
| Recruiting | Smartwatch-Based AI Model for OSA Prediction (SWOSA) NCT06792188 | Seoul National University Hospital | — |
| Recruiting | Cardiometabolic Risk Effects of Short-term Cessation of Neurostimulation Therapy NCT06720545 | Columbia University | N/A |
| Not Yet Recruiting | Obstructive Sleep Apnea Treatment in Serious Mental Illness NCT05457127 | University of California, San Diego | N/A |
| Completed | Reliability of the Samsung Galaxy for the Detection of Moderate to Severe Obstructive Sleep Apnea NCT06603441 | Stanford University | — |
| Completed | Pharmacological Treatment Targeting Endotypic Traits of Obstructive Sleep Apnea NCT06295562 | China Medical University Hospital | Phase 4 |
| Recruiting | Developing a Treatment Clustering System for Obstructive Sleep Apnea Using Polysomnographic Physiological Sign NCT06512779 | National Cheng-Kung University Hospital | N/A |
| Recruiting | OSA Risk Level in Dental Patients and Correlation With Complications After General Anesthesia NCT06430957 | Kırıkkale University | — |
| Recruiting | Effect of Inspiratory Muscle Training in Obstructive Sleep Apnea Syndrome. NCT06117579 | Centre Hospitalier Régional d'Orléans | N/A |
| Enrolling By Invitation | Imaging Predictors of Cryolysis Efficacy for Treatment of Obstructive Sleep Apnea NCT06434558 | University of Pennsylvania | — |
| Recruiting | Changes in Difficult Airway Markers After Surgery for Obstructive Sleep Apnoea Syndrome NCT06447818 | Kocaeli City Hospital | — |
| Recruiting | Impact GLP-1 Agonists Following Bariatric NCT06132477 | University of Missouri-Columbia | Phase 4 |
| Withdrawn | Mandibular Advancement Device (MAD) in Pregnant Women With Obstructive Sleep Apnea (OSA) NCT06256640 | Henry Ford Health System | N/A |
| Recruiting | Efficacy of Oropharyngeal Exercises for Patients With Obstructive Sleep Apnea Using Mandibular Advancement Dev NCT06103630 | National Cheng-Kung University Hospital | N/A |
| Recruiting | Management of Obstructive Sleep Apnea Syndrome by Expansion Palatoplasty NCT06283095 | ET Zarief | N/A |
| Unknown | Use of Intraoral Suction and Its Effects on Obstructive Sleep Apnea NCT05489562 | VA Boston Healthcare System | N/A |
| Recruiting | Clinical Trial of the Cryosa System for the Treatment of Obstructive Sleep Apnea NCT06008626 | Cryosa, Inc. | N/A |
| Recruiting | Melatonin's Effect on Nighttime Blood Pressure and Sleep in OSA Patients (MEBP-OSA) NCT06380491 | Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran | Phase 4 |
| Completed | Effectiveness of Telematic Instruction to Patients in the Correct Performance of Respiratory Polygraphy at Hom NCT06507098 | Consorci Sanitari del Maresme | N/A |
| Recruiting | Comprehensive Respiratory Training Exercise Program in Obstructive Sleep Apnea NCT05739617 | National Cheng-Kung University Hospital | N/A |
| Unknown | Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia NCT03255408 | University of Calgary | Phase 1 / Phase 2 |
| Recruiting | Vascular Endothelial Dysfunction in Sleep Apnea NCT05289063 | Columbia University | Phase 1 |
| Unknown | Cost-effectiveness Analysis and Conditional Response to the Effect of Positional Devices in Obstructive Sleep NCT05268471 | Hospital Universitario Ramon y Cajal | N/A |
| Unknown | Efficacy of Oropharyngeal Exercises for Patients With Obstructive Sleep Apnea Using Mandibular Advancement Dev NCT05717959 | National Cheng-Kung University Hospital | N/A |
| Recruiting | Effect of Smart Watch and App on PAP Adherence in OSA (Watch-OSA) NCT05530265 | Seoul National University Hospital | N/A |
| Completed | A Study to Investigate the Effects of Daridorexant on Nighttime Breathing in Patients With Shallow or Paused B NCT05458193 | Idorsia Pharmaceuticals Ltd. | Phase 1 |
| Terminated | Pilot Study of the CHILLS Cryotherapy System for the Treatment of OSA NCT05542082 | Cryosa, Inc. | N/A |
| Completed | Bibloc Mandibular Advancement Oral Device and Its Effect on TMJ Health NCT06492096 | Mansoura University | N/A |
| Unknown | A Pilot Study of Antioxidant Therapy in Obstructive Sleep Apnea Patients NCT05009901 | University of British Columbia | Phase 2 / Phase 3 |
| Unknown | Long COVID-19 Fatigue and Obstructive Sleep Apnea NCT05290350 | Centro Hospitalar Universitario do Algarve | — |
| Completed | ANNE Diagnostic Agreement With Home Sleep Testing NCT05421754 | Northwestern University | N/A |
| Completed | The Effects of Frequent Follow up on Compliance in Patients Receiving PAP Therapy Due to OSA (Pap: Positive Ai NCT05894733 | Istanbul Sureyyapasa Chest Diseases and Chest Surgery Training and Research Hospital | N/A |
| Completed | Acceptable Pressure Range for Continuous Positive Airway Pressure(CPAP) Treatment NCT04925466 | State Key Laboratory of Respiratory Disease | N/A |
| Completed | Comparative Study of the ANNE™ One System to Diagnose Obstructive Sleep Apnea NCT04643782 | Northwestern University | N/A |
| Completed | Periodontal Disease in Patients With Obstructive Sleep Apnea NCT04581798 | I.M. Sechenov First Moscow State Medical University | — |
| Completed | Acute and Long-term Effects of CPAP in OSA NCT06277115 | University of Zurich | N/A |
| Unknown | the Pathophysiology of the Onset of Atrial Fibrillation in Obstructive Sleep Apnea NCT06246825 | Catharina Ziekenhuis Eindhoven | — |
| Completed | Safety and Dosing Study of the CHILLS Cryotherapy for the Treatment of OSA NCT04864652 | Cryosa, Inc. | N/A |
| Unknown | The Relationship Between Obstructive Sleep Apnea and Alzheimer's Disease: Evidence and Effectiveness NCT05433883 | Chang Gung Memorial Hospital | N/A |
| Completed | Baseline Sleep Apnea Study #2 NCT04599803 | Verily Life Sciences LLC | N/A |
| Unknown | Myofunctional Therapy in Patients With Mild-moderate Sleep Apnea NCT04169984 | Hospital Universitario Ramon y Cajal | N/A |
| Unknown | Loop Gain in the Reversion of OSA Treated by Either CPAP or Cardiac Valve Replacement NCT03839654 | Nanjing Medical University | N/A |
| Unknown | Effect of Continuous Positive Airway Pressure on Chronotype, Dietary Intake, and Cardiovascular Risk Markers NCT04262960 | Hospital de Clinicas de Porto Alegre | N/A |
| Unknown | Real World Experiences of the iNAP® Lite in OSA Adults in Taiwan NCT03559322 | Somnics, Inc. | — |
| Unknown | Impact of Intermittent Hypoxia on the Function of the Phagocytes NCT03618719 | Taipei Veterans General Hospital, Taiwan | — |
| Completed | Cost-effectiveness Study of a Lifestyle Change Program for the Treatment of OSA and Obesity: Hospital-Primary NCT04296721 | Hospital Universitari de Bellvitge | N/A |
| Recruiting | Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy NCT03487185 | The George Washington University Biostatistics Center | N/A |
| Unknown | Voice Acoustic Properties in People With Obstructive Sleep Apnea Syndrome (OSAS) NCT03568240 | Hillel Yaffe Medical Center | — |
| Unknown | Vascular Responses After Percutaneous Coronary Intervention With Stenting In Patients With Obstructive Sleep A NCT04022824 | Beijing Anzhen Hospital | — |
| Completed | Change in Tongue Strength and Fatigue After Upper Airway Stimulation Therapy NCT03980158 | Technical University of Munich | — |
| Recruiting | A Cross-sectional Study Examining Adipose Tissue in Obstructive Sleep Apnea NCT03307330 | Mayo Clinic | — |
| Completed | Sodium, Nocturnal Blood Pressure and Nocturnal Pauses in Breathing NCT06022133 | Jesper Norgaard Bech | N/A |
| Completed | SleepWell24: An Innovative Smartphone Application to Improve PAP Adherence NCT03156283 | Arizona State University | N/A |
| Completed | Effects of Rehabilitation for Patients With Obstructive Sleep Apnea NCT03940781 | National Cheng-Kung University Hospital | N/A |
| Completed | Endothelial Function in Obstructive Sleep Apnea NCT03122639 | Columbia University | EARLY_Phase 1 |
| Completed | ThErapy Adherence Management in Veterans NCT03243487 | University of Florida | N/A |
| Completed | Does Race Make a Difference in Obstructive Sleep Apnea? NCT03463785 | Academic Centre for Dentistry in Amsterdam | — |
| Completed | Dexmedetomidine Added to Propofol for Drug Induced Sleep Endoscopy NCT03091894 | Essam Fathi | Phase 4 |
| Unknown | Assessment of Pulmonary Artery Pressure and Right Sided Hemodynamics in Patients With OSA Before and After CPA NCT03276611 | Assiut University | — |
| Completed | BiLAteral Hypoglossal Nerve Stimulation for Treatment of Obstructive Sleep Apnoea (BLAST OSA) NCT03048604 | Nyxoah S.A. | N/A |
| Completed | Obstructive Sleep Apnea and Bronchoscopy NCT03325153 | Seoul National University Hospital | — |
| Completed | Pilot Study of the MultiSense Patch to Record Cardiopulmonary Data During Sleep and Wake Cycles NCT02222103 | Scripps Translational Science Institute | — |
| Completed | OSA-ACS Project: Association of OSA and CPAP Therapy With Outcomes in ACS Patients NCT03362385 | Beijing Anzhen Hospital | — |
| Completed | Investigation of Predictive Indices to Objectively Guide Choice of CPAP Interface NCT03063567 | Singapore General Hospital | N/A |
| Completed | Sustainable Methods, Algorithms, and Research Tools for Delivering Optimal Care Study NCT02037438 | Stanford University | N/A |
| Unknown | Single Dose Morphine and Fentanyl Added to Intrathecal Mixture on Orthopedics Patients With Undiagnosed Obstru NCT02014714 | University of Malaya | Phase 1 |
| Completed | Inflammatory Markers in Obstructive Sleep Apnea (OSA) Patients. NCT03070769 | University of Crete | — |