Noonan Syndrome

27 registered clinical trials studyying Noonan Syndrome — 14 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Link Between Abnormal Bleeding and Coagulation Disorders in Noonan Syndromes NCT07259135	University Hospital, Bordeaux	—
Enrolling By Invitation	Palliative Care Needs of Children With Rare Diseases and Their Families NCT06938542	Children's National Research Institute	N/A
Recruiting	National Multicentre Study on Lipid Profile in Noonan Syndrome and Related Disorders: Trends by Age, Gender an NCT07464821	IRCCS Azienda Ospedaliero-Universitaria di Bologna	—
Recruiting	A Basket Study of Vosoritide in Children With Turner Syndrome, Short Stature Homeobox-Containing Gene Deficien NCT06668805	BioMarin Pharmaceutical	Phase 2
Recruiting	MEK Inhibitors for the Treatment of Hypertrophic Cardiomyopathy in Patients With RASopathies NCT06555237	Medical University of Warsaw	Phase 2
Completed	Lymphatic Phenotype in Noonan Syndrome Spectrum Disorders NCT06267807	Radboud University Medical Center	N/A
Recruiting	Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility S NCT05361811	National Cancer Institute (NCI)	N/A
Active Not Recruiting	A Research Study Looking at How Safe Somapacitan is and How Well it Works in Children Who Need Help to Grow - NCT05723835	Novo Nordisk A/S	Phase 3
Recruiting	Clinical, Genetic, and Epidemiologic Study of Children and Adults With RASopathies NCT04888936	National Cancer Institute (NCI)	—
Enrolling By Invitation	French Registry of Children Treated With Norditropin® for Short Stature Associated With Noonan Syndrome NCT05308927	Novo Nordisk A/S	—
Recruiting	Constitution of a Biological Collection to Study the Pathophysiology in Noonan Syndrome NCT05202210	University Hospital, Toulouse	—
Recruiting	Solid Tumors in RASopathies NCT05761314	Fondazione Policlinico Universitario Agostino Gemelli IRCCS	N/A
Recruiting	Effect of RAS/MAPK Pathway Hyperactivation on Growth' and Bone' Profile of the RASopathies NCT06331117	Fondazione Policlinico Universitario Agostino Gemelli IRCCS	N/A
Unknown	Prevalence and Characterization of Pain in RASopathies NCT06355622	Fondazione Policlinico Universitario Agostino Gemelli IRCCS	N/A
Completed	Joint and Hematologic Disorders of Noonan Syndrome: French Descriptive Cross-sectional Study NCT06550635	University Hospital, Brest	—
Recruiting	GROWing Up With Rare GENEtic Syndromes NCT04463316	dr. Laura C. G. de Graaff-Herder	—
Completed	Post Marketing Surveillance on Long-term Use With Norditropin® (Short Stature Due to Noonan Syndrome) NCT03435627	Novo Nordisk A/S	—
Recruiting	RASopathy Biorepository NCT04395495	Children's Hospital Medical Center, Cincinnati	—
Completed	Treatment With HMG-COA Reductase Inhibitor of Growth and Bone Abnormalities in Children With Noonan Syndrome NCT02713945	University Hospital, Toulouse	Phase 3
Completed	Hormonal Sensitivity in Patients With Noonan and LEOPARD Syndromes NCT02486731	Institut National de la Santé Et de la Recherche Médicale, France	—
Completed	Investigating the Long-term Efficacy and Safety of Two Doses of NN-220 (Somatropin) in Short Stature Due to No NCT01927861	Novo Nordisk A/S	Phase 3
Recruiting	Precision Diagnosis and Risk Stratification of Rare Cardiomyopathies Based on Novel Cardiac Magnetic Resonance NCT07336394	Chinese Academy of Medical Sciences, Fuwai Hospital	—
Completed	Genetic Testing of Noonan Subjects Previously Treated With Norditropin®. An Extension to Trial GHNOO-1658 NCT01529944	Novo Nordisk A/S	Phase 3
Completed	Observational Prospective Study on Patients Treated With Norditropin® NCT00960128	Novo Nordisk A/S	—
Completed	Effect of MAXOMAT ® on the Growth of Small Children to NOONAN's Syndrome NCT00452725	Sanofi	Phase 3
Completed	Somatropin Effect on Linear Growth and Final Height in Subjects With Noonan Syndrome NCT01529840	Novo Nordisk A/S	Phase 3
Terminated	Research Study Using Recombinant Human Insulin-Like Growth Factor-1/Recombinant Human Insulin-Like Growth Fact NCT00351221	Insmed Incorporated	Phase 2