| Not Yet Recruiting | Assessing DCog Short for Neurotoxicity in CAR-T NCT07403812 | Beth Israel Deaconess Medical Center | N/A |
| Recruiting | A Pilot Study for Pupillary Assessment to Predict CAR-T Related Neurotoxicity NCT06144151 | M.D. Anderson Cancer Center | — |
| Unknown | Assessment of Nerve Damage Biomarkers in Acute and Chronic Organophosphate Toxicity NCT06021262 | Alexandria University | — |
| Unknown | Effects of Lead Exposure on Ferroptosis Pathway NCT05950386 | Northern Jiangsu People's Hospital | — |
| Unknown | Electro-acupuncture for the Prevention and Treatment of Oxaliplatin-induced Neurotoxicity in Colorectal Cancer NCT05798884 | Hong Kong Baptist University | N/A |
| Recruiting | Tacrolimus Associated Tremors in Liver Transplantation: Immediate-Release Versus Extended-Release Formulations NCT05089604 | University of British Columbia | Phase 4 |
| Completed | Magnetic Resonance Imaging in Immune Effector Cell-Associated Neurotoxicity Syndrome NCT05510596 | University Hospital, Montpellier | N/A |
| Completed | Effect of Antibiotic Choice On ReNal Outcomes (ACORN) NCT05094154 | Vanderbilt University Medical Center | Phase 4 |
| Terminated | Serum Neurofilament Light (NfL) as a Marker for Brain Injury in Individuals Undergoing Chimeric Antigen Recept NCT04614987 | Washington University School of Medicine | — |
| Completed | EEG Encephalopathy Patterns in Immune Effectors Cells-associated Neurotoxicity Syndrome (ICANS)Lay Language NCT05040230 | University Hospital, Montpellier | — |
| Completed | A Phase 2 Trial of Anakinra for the Prevention of CAR-T Cell Mediated Neurotoxicity NCT04150913 | Marcela V. Maus, M.D.,Ph.D. | Phase 2 |
| Completed | Envarsus Neurotoxicity Burden in Liver Transplant Patients NCT03823768 | Medical University of South Carolina | Phase 4 |
| Completed | o Tadalafil for Prevention of Docetaxel-Induced Peripheral Neuropathy in Prostate Cancer NCT07333976 | Tri-Service General Hospital | Phase 2 |
| Completed | Effect of Tacrolimus Formulation on Neurological Side Effects in Older Kidney Transplant Recipients NCT03461445 | University of California, Davis | Phase 4 |
| Unknown | Clinical Trial of Electroacupuncture Stimulation on Prevention and Treatment of Oxaliplatin Neurotoxicity NCT03330964 | The First Affiliated Hospital of Dalian Medical University | N/A |
| Active Not Recruiting | A Study to Compare the Long-term Outcomes After Two Different Anaesthetics NCT03089905 | Murdoch Childrens Research Institute | Phase 3 |
| Completed | Neurotoxicity Evaluation of Beta-lactams in Intensive Care Unit and Identification of the Risk Factors NCT03628300 | Centre Hospitalier Universitaire, Amiens | — |
| Completed | Enzymatic Evaluation of General Anesthetic Induced Neurotoxicity in Patients With Aneurysmal Subarachnoid Hemo NCT03213392 | Mukilan Balu | — |
| Unknown | Monosialoganglioside Preventing Neurotoxicity Induced by Albumin-bound Paclitaxel Chemotherapy in Lung Cancer NCT02500810 | Peking University Cancer Hospital & Institute | Phase 2 |
| Completed | Monosialotetrahexosylganglioside for Treatment of Oxaliplatin Induced Neurotoxicity in Gastrointestinal Cancer NCT02486198 | Tianjin Medical University Cancer Institute and Hospital | Phase 3 |
| Completed | PAINTER: Polymorphism And INcidence of Toxicity in ERibulin Treatment NCT02864030 | Oncologia Medica dell'Ospedale Fatebenefratelli | Phase 4 |
| Completed | Advanced Neuroimaging Evaluation of CNS Changes Associated With Efavirenz Therapy Switch to an Raltegravir-bas NCT01978743 | Massachusetts General Hospital | N/A |
| Terminated | Study to Assess Prevention of Oxaliplatin-induced Neurotoxicity Through Vitamin D Pathway NCT01499940 | Gerald Higa, PharmD. | Phase 2 |
| Completed | Natural History of Brain Function, Quality of Life, and Seizure Control in Patients With Brain Tumor Who Have NCT01417507 | Radiation Therapy Oncology Group | — |
| Completed | Rituximab, Methotrexate, Vincristine Sulfate, Procarbazine Hydrochloride, and Cytarabine With or Without Radia NCT01399372 | Radiation Therapy Oncology Group | Phase 2 |
| Completed | Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor NCT01381718 | University of South Florida | Phase 2 |
| Completed | Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Hav NCT01372774 | Alliance for Clinical Trials in Oncology | Phase 3 |
| Completed | Peri-Anesthetic Imaging of Cognitive Dysfunction NCT01322672 | Vanderbilt University | — |
| Completed | Heavy Metal Exposure in Predicting Peripheral Neuropathy in Patients With Stage I-III Breast Cancer Undergoing NCT01982591 | Fox Chase Cancer Center | — |
| Terminated | Combination Chemotherapy Plus Bevacizumab With or Without Oxaliplatin in Treating Older Patients With Metastat NCT01279681 | Alliance for Clinical Trials in Oncology | Phase 3 |
| Terminated | Molecular-Genetic Mechanisms Associated With Chemotherapy-Induced Nerve Damage NCT01293851 | National Institute of Nursing Research (NINR) | — |
| Completed | Electrical Stimulation Pain Therapy in Treating Chronic Pain and Numbness Caused By Chemotherapy in Patients W NCT01196442 | Virginia Commonwealth University | N/A |
| Completed | Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Ca NCT01099449 | Alliance for Clinical Trials in Oncology | Phase 3 |
| Active Not Recruiting | Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma NCT00978458 | Eastern Cooperative Oncology Group | Phase 3 |
| Completed | S0715: Acetyl-L-Carnitine in Preventing Neuropathy in Women With Stage I, II, or IIIA Breast Cancer Undergoing NCT00775645 | SWOG Cancer Research Network | Phase 3 |
| Completed | Electrical Stimulation Therapy Using the MC5-A Scrambler in Reducing Peripheral Neuropathy Caused by Chemother NCT00952848 | Virginia Commonwealth University | Phase 2 |
| Completed | Acute Pain Caused by Paclitaxel in Patients With Cancer NCT00860041 | Alliance for Clinical Trials in Oncology | — |
| Withdrawn | Switching From One Type of Anti-rejection Drug (Tacrolimus or Cyclosporine) to Another (Sirolimus) Approximate NCT00834496 | Thomas Jefferson University | — |
| Withdrawn | Pilot Study of MGd + High-dose MTX-Based Chemoimmunotherapy + RT for Newly Dx PCNSL NCT00734773 | Northwestern University | EARLY_Phase 1 |
| Completed | Methotrexate, Glucarpidase, and Leucovorin in Treating Patients With Newly Diagnosed Primary Central Nervous S NCT00727831 | University College, London | Phase 1 / Phase 2 |
| Completed | Duloxetine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer NCT00489411 | Alliance for Clinical Trials in Oncology | Phase 3 |
| Completed | Memantine in Preventing Side Effects in Patients Undergoing Whole-Brain Radiation Therapy for Brain Metastases NCT00566852 | Radiation Therapy Oncology Group | Phase 3 |
| Completed | Combination Chemotherapy in Treating Younger Patients With Hodgkin Lymphoma NCT00666484 | University College, London | Phase 2 |
| Completed | Baclofen-Amitriptyline Hydrochloride-Ketamine Gel in Treating Peripheral Neuropathy Caused by Chemotherapy in NCT00516503 | Alliance for Clinical Trials in Oncology | Phase 3 |
| Completed | Bortezomib, Thalidomide, and Dexamethasone After Melphalan and Stem Cell Transplant in Treating Patients With NCT00792142 | City of Hope Medical Center | Phase 2 |
| Completed | Topical Amitriptyline and Ketamine Cream in Treating Peripheral Neuropathy Caused by Chemotherapy in Cancer Pa NCT00471445 | Gary Morrow | Phase 3 |
| Unknown | Biomarkers in Predicting Neurotoxicity in Patients With Colorectal Cancer Receiving Oxaliplatin NCT00884767 | Institut Cancerologie de l'Ouest | Phase 2 |
| Completed | Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer NCT00369564 | University of South Florida | Phase 3 |
| Completed | Effects of Chemotherapy on the Brain in Women With Newly Diagnosed Early-Stage Breast Cancer NCT00755313 | University of California, San Francisco | — |
| Terminated | L-Carnitine L-Tartrate in Preventing Peripheral Neuropathy Caused By Chemotherapy in Women With Metastatic Bre NCT00754767 | HealthPartners Institute | Phase 4 |
| Completed | Alpha-Lipoic Acid in Preventing Peripheral Neuropathy in Patients Receiving Chemotherapy for Cancer NCT00112996 | M.D. Anderson Cancer Center | Phase 3 |
| Completed | Vitamin E in Preventing Peripheral Neuropathy Caused by Chemotherapy in Patients Receiving Chemotherapy for Ca NCT00363129 | Alliance for Clinical Trials in Oncology | Phase 3 |
| Unknown | Treatment Outcome and Quality of Life in Patients With Pediatric Extra-Cranial Germ Cell Tumors Previously Tre NCT00436774 | Children's Cancer and Leukaemia Group | — |
| Completed | Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to th NCT00452868 | Wake Forest University Health Sciences | EARLY_Phase 1 |
| Terminated | D-cycloserine in the Management of Chemotherapy-Induced Peripheral Neuropathic Pain NCT00301080 | Northwestern University | Phase 3 |
| Terminated | Ph I Study of Lithium During Whole Brain Radiotherapy For Patients With Brain Metastases NCT00469937 | Vanderbilt-Ingram Cancer Center | Phase 1 |
| Completed | Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity Caused By Oxaliplatin in Patients Receivin NCT00316914 | Alliance for Clinical Trials in Oncology | Phase 3 |
| Completed | Hearing Loss and Dizziness in Patients Receiving Oxaliplatin for Solid Tumors NCT00305799 | Case Comprehensive Cancer Center | — |
| Completed | Nerve Changes in Patients Who Are Undergoing Chemotherapy or Biological Therapy for Cancer NCT00281853 | Case Comprehensive Cancer Center | — |
| Completed | Nerve Function in Older Diabetic Patients Who Are Undergoing Chemotherapy for Metastatic Solid Tumors NCT00263861 | Case Comprehensive Cancer Center | N/A |
| Completed | Glutamine in Treating Neuropathy Caused by Vincristine in Young Patients With Lymphoma, Leukemia, or Solid Tum NCT00365768 | Columbia University | Phase 2 |
| Completed | Neurobehavioral Complications in Children Who Were Previously Treated With Steroids and Intrathecal Therapy fo NCT00085176 | Children's Oncology Group | — |
| Completed | Amifostine in Treating Peripheral Neuropathy Caused by Paclitaxel in Patients With Solid Tumors NCT00078845 | M.D. Anderson Cancer Center | Phase 2 |
| Completed | Lamotrigine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer NCT00068445 | Alliance for Clinical Trials in Oncology | Phase 3 |
| Terminated | Adderall XR Compared With Concerta in Treating Young Cancer Patients With Memory, Attention, and Depression NCT00069927 | University of South Florida | Phase 2 |
| Completed | Amifostine in Treating Peripheral Neuropathy in Patients Who Have Received Chemotherapy for Cancer NCT00058071 | Gynecologic Oncology Group | Phase 3 |
| Completed | EGb761 in Maintaining Mental Clarity in Women Receiving Chemotherapy for Newly Diagnosed Breast Cancer NCT00046891 | Alliance for Clinical Trials in Oncology | Phase 3 |
| Completed | Brain Function in Children Previously Treated on Clinical Trials POG-9605 and POG-9201 NCT00028509 | Children's Oncology Group | — |
| Completed | Gabapentin in Treating Peripheral Neuropathy in Cancer Patients Undergoing Chemotherapy NCT00027963 | Alliance for Clinical Trials in Oncology | Phase 3 |
| Terminated | Amifostine in Treating Women With Ovarian, Peritoneal, Cervical, Fallopian Tube, Uterine, or Endometrial Cance NCT00003624 | Gynecologic Oncology Group | Phase 2 |
| Completed | Dimesna in Treating Patients With Solid Tumors Who Are Undergoing Treatment With Cisplatin and Paclitaxel NCT00003569 | Roswell Park Cancer Institute | — |
| Completed | Combination Chemotherapy in Treating Patients With Metastatic Ovarian Cancer or Non-small Cell Lung Cancer NCT00003072 | University of California, San Francisco | Phase 2 |
| Completed | Carboxypeptidase-G2 in Treating Nervous System Toxic Effects in Patients Given an Overdose of Intrathecal Meth NCT00018967 | National Cancer Institute (NCI) | N/A |