Trials / Withdrawn
WithdrawnNCT00834496
Switching From One Type of Anti-rejection Drug (Tacrolimus or Cyclosporine) to Another (Sirolimus) Approximately 90-180 Days After Liver Transplantation
Sirolimus Switching From Calcinurin Inhibitors (CNI) 90 - 180 Days After Liver Transplantation
- Status
- Withdrawn
- Phase
- —
- Study type
- Observational
- Enrollment
- 0 (actual)
- Sponsor
- Thomas Jefferson University · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Sirolimus can be safely switched as early as 90 days after liver transplantation with excellent tolerability and amelioration of the calcineurin inhibitor toxicity that initiated the switch.
Conditions
- Side Effects of Calcineurin Inhibitors
- Renal Toxicity
- Hepatic Fibrosis on Biopsy
- Neurotoxicity
- Post Transplant Diabetes
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Liver biopsy | percutaneous liver biopsy |
Timeline
- Start date
- 2009-01-01
- Primary completion
- 2010-01-01
- Completion
- 2010-01-01
- First posted
- 2009-02-03
- Last updated
- 2017-01-12
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00834496. Inclusion in this directory is not an endorsement.