| Not Yet Recruiting | Neprilysin Inhibition to Reduce Myocardial Fibrosis in Heart Failure With Preserved Ejection Fraction NCT06536309 | Brigham and Women's Hospital | Phase 4 |
| Not Yet Recruiting | A Health Coach-Led Digital Lifestyle Intervention (HEALDI) NCT07530562 | National University of Singapore | N/A |
| Recruiting | ⁶⁸Ga-FAPI PET/CT for Cardiac Fibrosis in Heart Failure NCT07296081 | University of Coimbra | — |
| Recruiting | High Relaxivity Contrast Agent for Cardiac MR in the Myocardial Scar Assessment NCT05954559 | Johns Hopkins University | Phase 4 |
| Not Yet Recruiting | Triple Combination Therapy (ARNI, SGLT2i, MRA) in Advanced HFpEF NCT06655480 | National Medical Research Center for Cardiology, Ministry of Health of Russian Federation | Phase 2 |
| Enrolling By Invitation | Quantification of Myocardial Fibrosis in Aortis Stenosis NCT06571175 | Norwegian University of Science and Technology | — |
| Recruiting | Fibrosis Assessment in Myocardial Infarction-associated Ventricular Aneurysm NCT06994221 | RenJi Hospital | — |
| Unknown | SPECT Fibroblast Activation Protein Imaging in Patients With Cardiac Disease NCT06326970 | Henan Institute of Cardiovascular Epidemiology | — |
| Unknown | Evaluate Aerobic Exercise on Myocardial Fibrosis and Intestinal Flora in Dilated Cardiomyopathy Diagnosed Firs NCT06039969 | Nanjing Medical University | — |
| Unknown | The Effect of Henagliflozin and Metformin on Myocardial Tissue-level Characteristics NCT06059287 | RenJi Hospital | N/A |
| Completed | Losartan in Prevention of Radiation-Induced Heart Failure NCT05607017 | Massachusetts General Hospital | EARLY_Phase 1 |
| Active Not Recruiting | Ultrahypofractionation and Normal Tissue Toxicity NCT05912231 | Massachusetts General Hospital | N/A |
| Unknown | Study of Novel PET Tracer Gallium [68Ga]/ Fluorine [18F] -FAPI-04 in the Diagnosis of Cardiovascular Diseases NCT05867589 | Nanjing First Hospital, Nanjing Medical University | N/A |
| Unknown | Pirfenidone Treat Myocardial Fibrosis After Acute Myocardial Infarction NCT05531955 | Shanghai Zhongshan Hospital | Phase 2 |
| Unknown | Liver Disease, Myocardial Fibrosis and Collaterals in the Adult Fontan Patient a Metabolomics and Proteomics A NCT04764305 | Medical University Innsbruck | — |
| Recruiting | Phase IA and IB Study of AAVrh.10hFXN Gene Therapy for the Cardiomyopathy of Friedreich's Ataxia NCT05302271 | Weill Medical College of Cornell University | Phase 1 |
| Completed | Imaging of Pathologic Fibrosis Using 68Ga-FAP-2286 NCT05180162 | Thomas Hope | Phase 1 |
| Unknown | Modulation of Fibrosis-inducing Pathways in Acute Myocardial Infarction NCT05122741 | University of Messina | — |
| Active Not Recruiting | Effect of Dapagliflozin in Myocardial Fibrosis and Ventricular Function in Patients With a ST-segment Elevatio NCT06619600 | Hospital Clinic of Barcelona | Phase 3 |
| Completed | PROFILE-MI - The FAPI Fibrosis Study NCT05356923 | University of Edinburgh | — |
| Completed | Effects of Aortic Valve Replacement on Myocardial T1 Values in Severe Aortic Valve Stenosis NCT05404100 | Rigshospitalet, Denmark | — |
| Completed | Ventricular Tachycardia Ablation and Myocardial Scar Characterization With Magnetic Resonance NCT04694079 | Azienda Ospedaliero, Universitaria Pisana | Phase 4 |
| Completed | The Assessment Of Myocardial Viability Based On CTA/MRI Hybrid Models NCT04397198 | Cardio Med Medical Center | — |
| Unknown | A Trial of Cardiac Injections of iMP Cells During CABG Surgery NCT03515291 | Cell Therapy Ltd. | Phase 2 |
| Completed | Effects of SGLT-2 Inhibition on Myocardial Fibrosis and Inflammation as Assessed by Cardiac MRI in Patients Wi NCT03782259 | University of Washington | Phase 4 |
| Withdrawn | MRI Assessment of Myocardial Fibrosis Associated With Monocyte Phenotype in End Stage Renal Failure NCT03857633 | Imperial College London | — |
| Completed | Mechanism of Decompensation Evaluation - Aortic Stenosis NCT03332745 | University of Edinburgh | — |
| Completed | MRI of Myocardial Infarction NCT03531151 | University of Pennsylvania | — |
| Completed | Ultrasonic Markers for Myocardial Fibrosis and Prognosis in Aortic Stenosis NCT03422770 | Norwegian University of Science and Technology | N/A |
| Unknown | Multimodality Biomarkers for Noninvasive Assessment of the Fontan Patient NCT03263312 | Maria Bano | N/A |
| Completed | Myocardial Perfusion and Fibrosis in Cancer Survivors NCT03191461 | Virginia Commonwealth University | — |
| Completed | Better Patient Selection to Transcatheter Aortic Valve Implantation NCT03107923 | Oslo University Hospital | — |
| Recruiting | IMPRoving Cardiovascular RiSk Stratification Using T1 Mapping in General populatION NCT04444128 | Johann Wolfgang Goethe University Hospital | — |
| Completed | Mechanisms of Diastolic Dysfunction Among Persons With HIV Compared With Non-HIV Control Subjects NCT02874703 | Massachusetts General Hospital | — |
| Completed | An Evaluation Of The Novel TRAMINER Sequence By Comparison To Late Gadolinium Enhancement Images NCT02727725 | Wake Forest University Health Sciences | N/A |
| Recruiting | Response of the Myocardium to Hypertrophic Conditions in the Adult Population NCT02670031 | National Heart Centre Singapore | — |
| Unknown | Left Ventricular Fibrosis in Chronic Kidney Disease NCT03176862 | Dr Manvir Kaur Hayer | — |
| Unknown | Role of Immune Responses After Acute Myocardial Infarction NCT02428374 | Federal University of São Paulo | Phase 4 |
| Completed | Validation of Fibrosis Quantification Using T1 Mapping Against Histology as Reference and Comparison With Fibr NCT02834104 | Assistance Publique Hopitaux De Marseille | N/A |
| Completed | Echocardiography Findings in Patients With Myocardial Fibrosis and Severe Aortic Stenosis NCT07331116 | Norwegian University of Science and Technology | — |
| Terminated | Molecular MRI of the Fibrotic Heart NCT02012725 | Moriel Vandsburger | — |
| Completed | Diffuse Myocardial Fibrosis in Fontan Patients NCT01929174 | Oregon Health and Science University | — |
| Unknown | Association of T1-mapping and LV Strain Analysis by CMR NCT03405987 | Medical University of Vienna | — |
| Completed | Noninvasive Imaging of Heart Failure: A Pilot Study NCT01160471 | National Institutes of Health Clinical Center (CC) | — |
| Completed | Cardiac MRI for Patients Enrolled in INFUSE-AMI NCT01059214 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Myocardial Fibrosis Progression in Duchenne and Becker Muscular Dystrophy - ACE Inhibitor Therapy Trial NCT02432885 | InCor Heart Institute | Phase 3 |
| Completed | Clinical and Therapeutic Implications of Fibrosis in Hypertrophic Cardiomyopathy NCT00879060 | Tufts Medical Center | Phase 4 |