| Not Yet Recruiting | Cardioprotective Effect of Melatonin Versus Vitamin D in Breast Cancer Patients Receiving Doxorubicin NCT07349459 | Tanta University | N/A |
| Recruiting | Oral Melatonin Versus Oral Pregabalin on Postoperative Pain and Anxiety Following Spine Surgery NCT07344467 | Tanta University | N/A |
| Completed | Effect of Fruit Elicitation With Melatonin on Human Health NCT07192835 | Universidad Miguel Hernandez de Elche | N/A |
| Not Yet Recruiting | Evaluating Efficacy and Safety of Oral Melatonin in Acute Central Serous Chorioretinopathy NCT06809751 | Mohsen Pourazizi | Phase 2 / Phase 3 |
| Not Yet Recruiting | Effects of 3-Month Melatonin Treatment on Regional Cerebellar Structure and Blood Biomarkers in Alzheimer's Di NCT06756828 | Saint Vincent's Hospital, Korea | N/A |
| Active Not Recruiting | Effects of Melatonin and Massage After Third Molar Surgery NCT06812026 | Bezmialem Vakif University | — |
| Recruiting | Light in Healthcare Environment (Ljus i sjukhusmiljö) NCT06687304 | Lund University | N/A |
| Recruiting | Idiopathic Scoliosis New Onset and Melatonin Phase Delay in Children NCT06502613 | Second Affiliated Hospital of Wenzhou Medical University | — |
| Completed | The Effect of Local Melatonin Application Around Immediately Placed Implants in the Maxillary Premolar NCT07103564 | Hams Hamed Abdelrahman | N/A |
| Unknown | Melatonin on Anxiety and Sleep Quality in Adults Undergoing Coronary Artery Bypass Graft Surgery NCT06237556 | Ain Shams University | N/A |
| Unknown | Dexmedetomidine Infusion Versus Oral Melatonin for Prevention of Intensive Care Delirium NCT06076668 | Tanta University | N/A |
| Completed | Effect of Suanzaoren Decoction and Huanglian Wendan Decoction on Biorhythm of Insomnia Patients NCT06467851 | The First Affiliated Hospital with Nanjing Medical University | N/A |
| Completed | Melatonin Effects on the Left Ventricular Function in Neonates With Persistent Pulmonary Hypertension NCT07090720 | Tanta University | N/A |
| Recruiting | Light in Frail Elderly - the Effect of a Dynamic Light for Sleep and Circadian Rhythm NCT05107947 | Region Skane | N/A |
| Completed | Effects of Melatonin Supplementation on Sleep Quality in Patients With Advanced Glaucoma NCT06868745 | University of Sao Paulo | N/A |
| Completed | Melatonin Supports Non Surgical Periodontal Treatment in Patients With Type 2 Diabetes and Periodontitis NCT05870358 | Yağmur Saraç Gül | Phase 4 |
| Completed | Salivary Melatonin Levels and Sleep Quality in Patients With Burning Mouth Syndrome NCT05309681 | University of Zagreb | — |
| Completed | Sedation and Nursing Management in EEG Recording in Children NCT05492812 | Suleyman Demirel University | N/A |
| Completed | Dexmedetomidine and Melatonin for Sleep Induction for EEG in Children NCT04665453 | University Medical Centre Ljubljana | N/A |
| Completed | Oral Melatonin as Neuroprotectant in Preterm Infants NCT04235673 | Francesca Garofoli | N/A |
| Unknown | Postpartum Depression NCT04278456 | Erzincan University | — |
| Unknown | Endogenous Melatonin Levels on Anxiety in Living Liver Donors NCT04230707 | Inonu University | — |
| Completed | Pharmacokinetics of Intravenous, Rectal, Intravesical, Vaginal, and Transdermal Melatonin in Healthy Female Vo NCT03519750 | Dennis Bregner Zetner | Phase 1 |
| Terminated | Melatonin for Renal Protection in Patients Receiving Polymyxin B NCT03725267 | Hospital de Clinicas de Porto Alegre | Phase 2 |
| Completed | Diabetic Retinopathy: Effects of Melatonin Treatment on Visual Functions and Circadian Rhythm NCT03478306 | Glostrup University Hospital, Copenhagen | Phase 3 |
| Completed | Interaction of Melatonin With MTNR1B Genotype on Glucose Control - Study 2 NCT03464084 | Brigham and Women's Hospital | N/A |
| Unknown | Use of Melatonin for Preventing POCD in Transurethral Prostate Resection Under Spinal Anesthesia NCT03966950 | University of Sao Paulo | N/A |
| Unknown | Melatonin Level and Postoperative Analgesia Consumption in Bariatric Surgery Patients. NCT03107702 | Inonu University | — |
| Unknown | Endogenous Melatonin Level and Pre- Postoperative Anxiety in Bariatric Surgery Patients. NCT03109054 | Inonu University | — |
| Unknown | Melatonin Use in the Intensive Care Elderly Population NCT03013790 | MICE Trial Group | Phase 4 |
| Completed | Interaction of Melatonin and MTNR1B Genotype on Glucose Control - Study 1 NCT02642640 | Brigham and Women's Hospital | N/A |
| Completed | Color-dependent Melatonin Suppression NCT02936674 | VA Palo Alto Health Care System | N/A |
| Completed | Melatonin for Cerebral Palsy Children's Sleep and Health NCT04392063 | Ain Shams University | N/A |
| Completed | Plasma Melatonin AND Mortality After Acute Myocardial Infarction NCT03230630 | Chinese PLA General Hospital | — |