| Recruiting | Evaluating the Long-term Safety and Tolerability of Imatinib in Patients With Lymphangioleiomyomatosis (LAM) NCT06889168 | Columbia University | Phase 1 |
| Recruiting | Tuberous Sclerosis Complex and Lymphangioleiomyomatosis Pregnancy Registry (TSC-LAM Registry) NCT06160310 | David M. Ritter | — |
| Enrolling By Invitation | Breath Analysis and Arterial Stiffness in Patients With Respiratory Diseases NCT05727852 | I.M. Sechenov First Moscow State Medical University | — |
| Completed | Lymphangioleiomyomatosis, a Study on Cathepsin K NCT05323370 | University Hospital, Tours | — |
| Unknown | Characterizing LAM With 11C-Choline PET/CT NCT05087134 | Peking Union Medical College Hospital | EARLY_Phase 1 |
| Unknown | Effect of Loratadine in Lymphangioleiomyomatosis NCT05190627 | Institut d'Investigació Biomèdica de Bellvitge | Phase 2 |
| Active Not Recruiting | Feasibility of [11C]Acetate-PET in LAM and TSC NCT05467397 | Brigham and Women's Hospital | Phase 1 / Phase 2 |
| Unknown | Sleep Patterns in Patients Affected by Lymphangioleiomiomatosis NCT04577937 | dr. Stefano Nava | N/A |
| Completed | Benefits of Pulmonary Rehabilitation in Patients With Severe Lymphangioleiomyomatosis (LAM) NCT04184193 | Schön Klinik Berchtesgadener Land | — |
| Terminated | Biomarkers for Tuberous Sclerosis Complex (BioTuScCom) NCT02654340 | CENTOGENE GmbH Rostock | — |
| Completed | Resveratrol and Sirolimus in Lymphangioleiomyomatosis Trial NCT03253913 | University of Cincinnati | Phase 2 |
| Completed | LAM Pilot Study With Imatinib Mesylate NCT03131999 | Medical University of South Carolina | Phase 1 / Phase 2 |
| Active Not Recruiting | Multicenter Interventional Lymphangioleiomyomatosis (LAM) Early Disease Trial NCT03150914 | University of Cincinnati | Phase 3 |
| Completed | Discovery of Sirolimus Sensitive Biomarkers in Blood NCT03304678 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 2 |
| Completed | A Study of Nintedanib for LymphAngioleioMyomatosis (LAM) NCT03062943 | IRCCS Multimedica | Phase 2 |
| Completed | The Effect of Lt to Rt Shunt Using Veno-veno-arterial Extracorporeal Membrane Oxygenation (ECMO) on Coronary O NCT02859194 | Yonsei University | N/A |
| Completed | Characterization of Patients With Tuberous Sclerosis Complex, Lymphangioleiomyomatosis and Angiomyolipoma NCT02325505 | InCor Heart Institute | — |
| Recruiting | TSC Biosample Repository and Natural History Database NCT05676099 | National Tuberous Sclerosis Association | — |
| Recruiting | Safety and Durability of Sirolimus for Treatment of LAM NCT02432560 | University of Cincinnati | — |
| Completed | Safety of Simvastatin in LAM and TSC NCT02061397 | University of Pennsylvania | Phase 1 / Phase 2 |
| Completed | Pulmonary Rehabilitation in Lymphangioleiomyomatosis NCT02009241 | University of Sao Paulo General Hospital | N/A |
| Recruiting | Nebulized or Inhaled Albuterol for Lymphangioleiomyomatosis NCT01799538 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 1 / Phase 2 |
| Completed | Safety Study of Sirolimus and Hydroxychloroquine in Women With Lymphangioleiomyomatosis NCT01687179 | Brigham and Women's Hospital | Phase 1 |
| Active Not Recruiting | Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With NCT01552434 | M.D. Anderson Cancer Center | Phase 1 |
| Recruiting | National Lymphangioleiomyomatosis Registry, France NCT01484236 | Vincent COTTIN | — |
| Completed | Letrozole for Lymphangioleiomyomatosis NCT01353209 | University of Cincinnati | Phase 2 |
| Completed | A Study to Determine the Safety and Effectiveness of RAD001 (Everolimus) in Patients With Lymphangioleiomyomat NCT01059318 | Novartis Pharmaceuticals | Phase 2 |
| Completed | Pulmonary Hypertension in Lymphangioleiomyomatosis NCT00960895 | Groupe d'Etudes et de Recherche sur les Maladies Orphelines Pulmonaires | — |
| Completed | Doxycycline In Lymphangioleiomyomatosis (LAM) NCT00989742 | University of Nottingham | Phase 4 |
| Completed | Effect of Fasting on the Size of Abdominal Lymphatic Tumors in Women NCT00552955 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Efficacy and Safety of Sirolimus in LAM NCT00414648 | University of Cincinnati | Phase 3 |
| Completed | Role of Helicobacter Pylori and Its Toxins in Lung and Digestive System Diseases NCT00366509 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Unknown | Trial of Efficacy and Safety of Sirolimus in Tuberous Sclerosis and LAM NCT00490789 | Cardiff University | Phase 2 |
| Completed | RAD001 Therapy of Angiomyolipomata in Patients With TS Complex and Sporadic LAM NCT00457964 | Children's Hospital Medical Center, Cincinnati | Phase 1 / Phase 2 |
| Completed | Rapamycin Therapy for Patients With Tuberous Sclerosis Complex and Sporadic LAM NCT00457808 | Children's Hospital Medical Center, Cincinnati | Phase 2 |
| Completed | Treatment With Octreotide in Patients With Lymphangioleiomyomatosis NCT00005906 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 2 |
| Recruiting | Study of the Disease Process of Lymphangioleiomyomatosis NCT00001465 | National Heart, Lung, and Blood Institute (NHLBI) | — |