| Recruiting | Safety and Efficacy of ONT01 in Lupus NCT07107659 | Hospital for Special Surgery, New York | EARLY_Phase 1 |
| Not Yet Recruiting | C-CAR168 CAR T Cell Therapy for Refractory Autoimmune Disease NCT06935474 | AbelZeta Inc. | Phase 1 / Phase 2 |
| Not Yet Recruiting | Efficacy and Safety of CD19 CAR-γδ T Cells in the Treatment of Relapsed/Refractory Autoimmune Nephropathy NCT07535138 | Air Force Military Medical University, China | EARLY_Phase 1 |
| Recruiting | A Phase 1 Study of HB2198 in Participants With Moderately to Severely Active Systemic Lupus Erythematosus (SLE NCT07491900 | Hinge Bio | Phase 1 |
| Not Yet Recruiting | Efficacy and Safety of CRC01 in Participants With Severe, Refractory Systemic Lupus Erythematosus NCT07364396 | Curocell Inc. | Phase 1 / Phase 2 |
| Not Yet Recruiting | Dapagliflozin in Active Lupus Nephritis NCT07323524 | Brigham and Women's Hospital | Phase 4 |
| Not Yet Recruiting | BCMA-CD19 cCAR T for the Treatment of Refractory Lupus NCT07328581 | iCell Gene Therapeutics | Phase 1 / Phase 2 |
| Recruiting | Dose Escalation Study With Bispecific Antibodies in Adult Patients With Lupus Nephritis NCT06975787 | Regeneron Pharmaceuticals | Phase 1 |
| Recruiting | The Efficacy and Safety of Biologics (Belimumab/ Telitacicept) Induction Therapy in Proliferative Lupus Nephri NCT07340463 | Nanjing University School of Medicine | Phase 2 |
| Recruiting | An Exploratory Clinical Study of YTS109 Cell for R/R Autoimmune Diseases NCT07236762 | China Immunotech (Beijing) Biotechnology Co., Ltd. | Phase 1 |
| Recruiting | Study to Assess Efficacy and Safety of HSK39297 Tablets in Patients With LN NCT07363460 | Haisco Pharmaceutical Group Co., Ltd. | Phase 2 |
| Not Yet Recruiting | The Relation of Albumin/Globulin Ratio and Platelet/Albumin Ratio to Lupus Nephritis NCT07130448 | Assiut University | — |
| Not Yet Recruiting | SGLT-2 Inhibitors on Albuminuria in Chronic Kidney Disease Patients With Lupus Nephritis and ANCA- Associated NCT07035834 | Federico II University | Phase 4 |
| Recruiting | A Clinical Study of YTS109 Cells for the Treatment of R/R Autoimmune Diseases NCT07123519 | China Immunotech (Beijing) Biotechnology Co., Ltd. | Phase 1 |
| Recruiting | A Study to Evaluate the Efficacy, Safety, and Tolerability of Human Sialidase Fusion Protein (HLX79) in Combin NCT07038382 | Shanghai Henlius Biotech | Phase 2 |
| Recruiting | A Clinical Study of YTS109 Cell for R/R Autoimmune Diseases NCT07104721 | China Immunotech (Beijing) Biotechnology Co., Ltd. | Phase 1 |
| Not Yet Recruiting | MSC303 Subcutaneous Injection for the Treatment of Immunologic Glomerular Disease. NCT07000292 | Shanghai Changzheng Hospital | Phase 1 / Phase 2 |
| Recruiting | CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus NCT06839976 | Children's Hospital of Philadelphia | Phase 1 / Phase 2 |
| Recruiting | A Clinical Study of YTS109 Cell in R/R Systemic Lupus Erythematosus NCT06943937 | China Immunotech (Beijing) Biotechnology Co., Ltd. | Phase 1 |
| Recruiting | Equecabtagene Autoleucel Injection (Eque-cel) for Relapsed/Refractory Systemic Lupus Erythematosus (SLE) NCT06902844 | Tongji Hospital | N/A |
| Not Yet Recruiting | Urinary Congophilia as an Indicator of Activity of Lupus Nephritis NCT06654024 | Assiut University | — |
| Recruiting | Anti-CD19 Chimeric Antigen Receptor T Cells for Refractory Systemic Lupus Erythematosus NCT06585514 | Beijing GoBroad Hospital | Phase 1 / Phase 2 |
| Not Yet Recruiting | Renal Survival in Patients with Lupus Nephritis NCT06588192 | Assiut University | — |
| Withdrawn | A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN NCT06419205 | Q32 Bio Inc. | Phase 2 |
| Withdrawn | Atacicept in Subjects With Active Lupus Nephritis (COMPASS) NCT05609812 | Vera Therapeutics, Inc. | Phase 3 |
| Recruiting | Research Accelerated by You Lupus Registry NCT06927219 | Lupus Foundation of America | — |
| Recruiting | High Quality Evidence of Guangzhou Lupus Nephritis Cohort (HOPE Cohort) NCT06682507 | First Affiliated Hospital, Sun Yat-Sen University | — |