Clinical Trials Directory

Trials / Conditions / Leptomeningeal Disease

Leptomeningeal Disease

14 registered clinical trials studyying Leptomeningeal Disease — 9 currently recruiting.

StatusTrialSponsorPhase
Not Yet RecruitingOptimizing Contrast Dose and Scanning Parameters for Detection of Leptomeningeal Disease
NCT07415018
M.D. Anderson Cancer CenterN/A
Not Yet RecruitingB7-H3.CD28Z.CART in CNS Neoplasms
NCT07390539
Robbie MajznerPhase 1
RecruitingNon Interventional German Leptomeningeal Disease Register
NCT06146010
University Hospital Tuebingen—
RecruitingCapecitabine, Tucatinib, and Intrathecal Trastuzumab for Breast Cancer Patients With Leptomeningeal Disease
NCT05800275
UNICANCERPhase 2
RecruitingA First in Human Dose Escalation of Dendritic Cell Vaccine (DCV)
NCT05809752
H. Lee Moffitt Cancer Center and Research InstitutePhase 1
TerminatedA Therapy Treatment Response Trial in Patients With Leptomeningeal Metastases ((LM) Using CNSide
NCT05414123
Biocept, Inc.—
Active Not RecruitingStudy Assessing QBS72S For Treating Brain Metastases
NCT05305365
Stanford UniversityPhase 2
RecruitingStandardized Clinical Assessment of Patients With Leptomeningeal Metastasis
NCT06417710
University of Zurich—
RecruitingIntrathecal Application of PD1 Antibody in Metastatic Solid Tumors With Leptomeningeal Disease (IT-PD1/ NOA 26
NCT05112549
University Hospital TuebingenPhase 1
RecruitingRadiation Therapy Followed by Intrathecal Trastuzumab/Pertuzumab in HER2+ Breast Leptomeningeal Disease
NCT04588545
H. Lee Moffitt Cancer Center and Research InstitutePhase 1 / Phase 2
CompletedAvelumab With Radiotherapy in Patients With Leptomeningeal Disease
NCT03719768
H. Lee Moffitt Cancer Center and Research InstitutePhase 1
TerminatedTucatinib, Trastuzumab, and Capecitabine for the Treatment of HER2+ LMD
NCT03501979
University of Alabama at BirminghamPhase 2
TerminatedAfatinib on CNS Metastases and LMD in EGFR Mutation Positive NSCLC
NCT03711422
National Cancer Centre, SingaporePhase 1
RecruitingProspective Evaluation Of High-Dose Systemic Methotrexate In Patients With Breast Cancer And Leptomeningeal Me
NCT02422641
Wake Forest University Health SciencesPhase 2