| Not Yet Recruiting | EArly Effect of Glucocorticoid on Incidence of Persistent Left BundlE Branch Block (LBBB) Post-TAVR (EAGLE-TAV NCT06762145 | Xiao-dong Zhuang | Phase 4 |
| Recruiting | Management of Patients With New Left Bundle Branch Block After Transcatheter Aortic Valve Implantation NCT06148883 | Assistance Publique Hopitaux De Marseille | N/A |
| Recruiting | Left Bundle Branch Pacing on Outcomes and Ventricular Remodeling in Biventricular CRT Nonresponders NCT05760924 | Tomsk National Research Medical Center of the Russian Academy of Sciences | N/A |
| Active Not Recruiting | Left Bundle Branch Area Pacing in Patients With Heart Failure NCT06488989 | National Research Center for Cardiac Surgery, Kazakhstan | N/A |
| Recruiting | UHF ECG in LBBB and Response to CRT Prediction NCT07057544 | Faculty Hospital Kralovske Vinohrady | N/A |
| Recruiting | HIS Alternative II - UK Site NCT05814263 | Imperial College Healthcare NHS Trust | N/A |
| Unknown | A Study to Evaluate Accuracy and Validity of the Chang Gung ECG Abnormality Detection Software NCT05903313 | Chang Gung Memorial Hospital | — |
| Recruiting | Conventional Biventricular Versus Left Bundle Branch Pacing on Outcomes in Heart Failure Patients NCT05769036 | Tomsk National Research Medical Center of the Russian Academy of Sciences | N/A |
| Recruiting | Left Bundle Branch Area Mapping for Conduction System Pacing NCT05884359 | Steward St. Elizabeth's Medical Center of Boston, Inc. | — |
| Recruiting | Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment NCT05327062 | XSpline S.p.A. | N/A |
| Active Not Recruiting | REsynchronization Comparison In LBBB and Normal or Mildly Reduced VENTricular Function With CRT (REINVENT-CRT) NCT05652218 | Inova Health Care Services | N/A |
| Recruiting | ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacin NCT06324682 | University Hospital of Ferrara | — |
| Completed | Effects of Isolated LBBB on Maximal Functional Capacity NCT05643404 | Fundación para la Investigación del Hospital Clínico de Valencia | — |
| Completed | BIOTRONIK Conduction System Pacing With the Solia Lead NCT05251363 | Biotronik, Inc. | N/A |
| Completed | Conduction System Pacing Versus Biventricular Resynchronization in Patients With Chronic Heart Failure NCT05572736 | Hospital Moinhos de Vento | N/A |
| Recruiting | LBBP as Initial Therapy in Patients With Non-ischemic Heart Failure and LBBB NCT05572957 | The First Affiliated Hospital with Nanjing Medical University | N/A |
| Recruiting | Absolute Coronary Flow in Patients With Heart Failure With Reduced Ejection Fraction and Left Bundle Branch Bl NCT05564689 | Ashkan Eftekhari | — |
| Active Not Recruiting | The Left Bundle Cardiac Resynchronization Therapy Trial NCT05434962 | Óscar Cano Pérez | N/A |
| Completed | Conduction System Pacing Versus Biventricular Pacing for Cardiac ResYNChronization NCT05155865 | University Medical Centre Ljubljana | N/A |
| Terminated | Acute Hemodynamic Effects of Pacing the His Bundle in Heart Failure NCT04701112 | Region Skane | N/A |
| Recruiting | Prediction of Outcome by Echocardiography in Left Bundle Branch Block NCT04293471 | University Hospital of North Norway | — |
| Completed | Direct HIS/LBB Pacing as an Alternative to Biventricular Pacing in Patients With HFrEF and a Typical LBBB. NCT04409119 | Rigshospitalet, Denmark | N/A |
| Unknown | Clinical, Structural and Mechanical Features in Patients With Left Bundle Branch Block. NCT04328649 | Policlinico Casilino ASL RMB | — |
| Completed | Mid-Q Response Study NCT04180696 | Medtronic Cardiac Rhythm and Heart Failure | N/A |
| Withdrawn | Optimised MultiSite Pacing Vector Study NCT03938090 | Barts & The London NHS Trust | N/A |
| Completed | Mechanisms and Innovations in Cardiac Resynchronisation Therapy NCT04221763 | Imperial College London | N/A |
| Completed | Non-invasive Mapping Using Ultra-high Frequency Electrocardiography NCT04537455 | Imperial College London | N/A |
| Completed | Mapping and Pacing of the His Bundle for Heart Failure Patients With Left Bundle Branch Block NCT03803995 | Abbott Medical Devices | N/A |
| Completed | LV Only MPP With SyncAV NCT03567096 | Abbott Medical Devices | N/A |
| Completed | Direct HIS-pacing as an Alternative to BiV-pacing in Symptomatic HFrEF Patients With True LBBB NCT03614169 | Rigshospitalet, Denmark | N/A |
| Unknown | Infranodal Conduction Time During TAVR as Predictor of HAVB NCT04128384 | University Hospital, Saarland | N/A |
| Recruiting | Pacing to Maintain Physiologic Ventricular Activation NCT04416958 | Klinikum-Fuerth | — |
| Terminated | Optimizing CRT With ECGI NCT03492788 | Washington University School of Medicine | N/A |
| Unknown | Left Ventricular Septal Pacing: Potential Application for Cardiac Resynchronization Therapy NCT03415945 | Maastricht University Medical Center | N/A |
| Recruiting | Clinical Monitoring Strategy Versus Electrophysiology-guided Algorithmic Approach With a New LBBB After TAVI NCT03303612 | Montreal Heart Institute | N/A |
| Completed | Study on Heart Block Risks Using Outcome-Based Modeling NCT07065123 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | — |
| Withdrawn | LV Endocardial CRT for Patients With Intermediate QRS Width NCT03573427 | Jaimie Manlucu | — |
| Unknown | HV Electrophysiology Study In Transcatheter Aortic Valve Implantation Patients NCT02659137 | Maastricht University Medical Center | — |
| Unknown | Myocardial Work and Metabolism in CRT NCT02537782 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Completed | Adaptive CRT Effect on Electrical Dyssynchrony NCT02543281 | Larisa Tereshchenko | N/A |
| Terminated | Left Bundle Branch Block ECG Characteristics in the Evaluation of Acute Coronary Syndrome NCT02283619 | Duke University | — |
| Completed | Tailor-CRT: Better Application of Cardiac Resynchronization Therapy NCT02326493 | Maastricht University Medical Center | N/A |
| Terminated | MADIT ASIA Cardiac Resynchronization Trial NCT01872234 | Boston Scientific Corporation | Phase 3 |
| Completed | EP-Catheter Guided CS-Lead Implantation NCT01922544 | University of Cologne | — |
| Terminated | MIRACLE EF Clinical Study NCT01735916 | Medtronic Cardiac Rhythm and Heart Failure | N/A |
| Completed | QT Interval in Patients With Pacemaker Dependency NCT01694550 | University of Magdeburg | — |
| Terminated | High Septal Pacing for Cardiac Resynchronization Therapy NCT01325480 | Boston Scientific Corporation | — |
| Unknown | Resynchronization in Paced Heart Failure Patients With Implantable Cardioverter Defibrillator (ICD) Indication NCT01415024 | Schuechtermann-Klinik | Phase 4 |
| Completed | Optimal Coronary Sinus Lead Implantation Using Intracardiac Impedography and Magnetic Resonance Imaging NCT01129635 | Emory University | N/A |