Clinical Trials Directory

Trials / Completed

CompletedNCT04537455

Non-invasive Mapping Using Ultra-high Frequency Electrocardiography

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
30 (actual)
Sponsor
Imperial College London · Academic / Other
Sex
All
Age
18 Years – 100 Years
Healthy volunteers
Accepted

Summary

Cardiac electrical mapping is an important tool that allows doctors to study the electrical activity of the heart in detail. Electrical mapping systems used in clinical practice are time consuming, invasive and very costly. Ultra-high frequency electrocardiography is a novel non-invasive cardiac mapping system. Ultra-high frequency electrocardiography (UHF-ECG) can be performed in 10-15 minutes without any risk or discomfort to patients. The aim of this study is to refine this mapping system, verify it against invasive mapping and develop software to bring this novel system into routine clinical use including predicting which patients will respond to cardiac resynchronisation therapy.

Detailed description

This is a single centre laboratory study aiming to utilise ultra-high frequency electrocardiography to construct cardiac electrical activation maps. All participants will attend for an UHF-ECG. This involves placing standard electrocardiography electrodes (up to 48) followed by electrocardiography recording using the UHF-ECG machine for 10-15 minutes. Participants undergoing a clinically indicated VT ablation procedure will their UHF-ECG done before the procedure at a separate time. The ablation procedure itself will proceed as standard with no alternation whatsoever in study participants and no invasive measurements will be undertaken during the procedure. After the procedure is complete the 3D electrical maps collected to guide VT ablation will be analyzed and used for the study. The invasive maps will be compared with the non-invasive maps obtained using UHF-EGC.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TESTUltra-high frequency electrocardiographyPatients will have an ultra-high frequency electrocardiography performed.

Timeline

Start date
2019-10-01
Primary completion
2023-12-10
Completion
2024-03-10
First posted
2020-09-03
Last updated
2024-04-23

Locations

1 site across 1 country: United Kingdom

Source: ClinicalTrials.gov record NCT04537455. Inclusion in this directory is not an endorsement.