Trials / Unknown
UnknownNCT02537782
Myocardial Work and Metabolism in CRT
Investigating Inhomogeneities of Regional Myocardial WORKload and Metabolism in a Cardiac Resynchronisation Therapy Patient Population
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 200 (estimated)
- Sponsor
- Universitaire Ziekenhuizen KU Leuven · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Several attempts have been made to refine selection criteria for cardiac resynchronisation therapy (CRT) in heart failure patients with reduced ejection fraction (HFrEF). Previously proposed parameters probably do not sufficiently reflect the underlying mechanical dyssynchrony of the left ventricle (LV). Earlier work of our research group suggests that better candidate selection can rely on the direct observation or measurement of this LV mechanical dyssynchrony by means of non-invasive imaging. In this study apical rocking and other non-invasive measures of LV mechanical dyssynchrony will be applied to evaluate regional myocardial workload and metabolism, and determine their predictive value in CRT response.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | Cardiac resynchronisation therapy | |
| OTHER | Echocardiography | |
| OTHER | Magnetic Resonance Imaging | |
| OTHER | Positron Emission Tomography |
Timeline
- Start date
- 2015-09-01
- Primary completion
- 2018-12-01
- Completion
- 2023-12-01
- First posted
- 2015-09-02
- Last updated
- 2020-01-09
Locations
2 sites across 2 countries: Belgium, Norway
Source: ClinicalTrials.gov record NCT02537782. Inclusion in this directory is not an endorsement.