| Not Yet Recruiting | CApecitabine Prior to TUmor Resection in Ent Oncology (CAPTURE) NCT07254962 | Sir Mortimer B. Davis - Jewish General Hospital | Phase 2 |
| Recruiting | A Study of Sacituzumab Govitecan in Combination With Cetuximab in People With Head and Neck Squamous Cell Canc NCT07063212 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Recruiting | Lymphocyte-Sparing And Radio-Immunotherapy in Head and Neck Carcinoma NCT06706401 | Centre Leon Berard | Phase 3 |
| Completed | Evaluations of Alcohol Warning Labels NCT06129487 | University of Connecticut | N/A |
| Withdrawn | A Study of Concurrent Chemoradiation in Combination With or Without PD1 Inhibitor AB122 Adenosine 2a Receptor NCT04892875 | Jennifer Choe | Phase 1 |
| Recruiting | Multi-Site Trial of Navigation vs Treatment as Usual to Improve Initiation of Timely Adjuvant Therapy NCT05793151 | Medical University of South Carolina | N/A |
| Recruiting | Neoadjuvant Chemoimmunotherapy Followed By Radiation Or Organ Preservation Surgery In Laryngeal/Hypopharyngeal NCT06039631 | Fudan University | Phase 2 |
| Withdrawn | GI Organ Tracking Via Balloon Applicators NCT05471401 | Washington University School of Medicine | N/A |
| Active Not Recruiting | The ENHANCE Study: Exercise and Nutrition in Head And Neck CancEr Survivors NCT05798780 | H. Lee Moffitt Cancer Center and Research Institute | N/A |
| Completed | Phonatory Movement of the Pharyngoesophageal Mucosa in Laryngectomy Patients NCT05561920 | Osijek University Hospital | — |
| Unknown | Immunological Function After Radiation With Either Proton or Photon Therapy NCT06016699 | University Medical Center Groningen | — |
| Completed | Evaluation of the French Translation of Swallowing (SOAL-VF) Patient Reported Outcomes (PRO) After Total Phary NCT05497947 | Centre Hospitalier de Valence | — |
| Recruiting | Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy NCT05337631 | University Hospital Freiburg | — |
| Completed | The Registry of Oncology Outcomes Associated With Testing and Treatment NCT04028479 | Taproot Health | — |
| Unknown | Quality of Life and Voice Perception in Patients Laryngoctomized Phonatory Wearers NCT06086119 | Regina Elena Cancer Institute | — |
| Recruiting | CONFIRM: Magnetic Resonance Guided Radiation Therapy NCT04368702 | Brigham and Women's Hospital | N/A |
| Completed | Bilateral Elective Neck Dissection in Salvage Total Laryngectomy NCT05746780 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Recruiting | VoiceS: Voice Quality After Transoral CO2-Laser Surgery Versus Single Vocal Cord Irradiation for Larynx Cancer NCT04057209 | Olgun Elicin | N/A |
| Active Not Recruiting | Vocal-cord vs. Complete Laryngeal Radiotherapy for Early Glottic Cancer NCT03759431 | Centre hospitalier de l'Université de Montréal (CHUM) | Phase 2 |
| Completed | Comparison Between a Standard Tube and the Ultra-thin Tritube for Intubation of the Trachea and for Maintainin NCT03653039 | Michael Seltz Kristensen | N/A |
| Completed | Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Ge NCT03602079 | Klus Pharma Inc. | Phase 1 / Phase 2 |
| Completed | An Investigation of Biomarker Candidate Molecules in Laryngeal Carcinoma NCT05217147 | Hacettepe University | — |
| Terminated | Use of Human Dehydrated Amnion Chorion Allograft in Laryngectomy/Pharyngectomy NCT03479463 | MiMedx Group, Inc. | — |
| Active Not Recruiting | Carboplatin, Nab-Paclitaxel, Durvalumab Before Surgery and Adjuvant Therapy in Head and Neck Squamous Cell Car NCT03174275 | UNC Lineberger Comprehensive Cancer Center | Phase 2 |
| Completed | WEE1 Inhibitor with Cisplatin and Radiotherapy: a Trial in Head and Neck Cancer NCT03028766 | University of Birmingham | Phase 1 |
| Completed | Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell Carcinom NCT03082534 | University of California, San Diego | Phase 2 |
| Completed | Adaptive Radiotherapy for Head and Neck Cancer NCT03096808 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Unknown | Cell-free Tumor DNA in Head and Neck Cancer Patients NCT03942380 | Christian von Buchwald | N/A |
| Completed | Pembrolizumab in Combination With CRT for LA-SCCHN NCT02586207 | Sanford Health | Phase 1 |
| Completed | Evaluation of a Web-based Decision Aid Tool for Larynx Cancer (T3/T4) Patients. NCT03292341 | Maastricht Radiation Oncology | N/A |
| Completed | Breath Testing in Early and Late Larynx Cancer NCT01700647 | Royal Brisbane and Women's Hospital | — |
| Unknown | Induction Docetaxel/Cisplatin/5-fluorouracil (TPF) as Selector for Chemo Radiation Therapy (RT) Versus Partial NCT01073683 | Rabin Medical Center | Phase 2 |
| Completed | Transoral Laser Surgery and Radiotheraphy for Early Stage Laryngeal Squamous Cell Cancer NCT04778306 | Saglik Bilimleri Universitesi | N/A |
| Completed | Clinical Feasibility of New Tracheoesophageal Puncture Set NCT01045057 | Atos Medical AB | N/A |
| Terminated | MRI Laryngeal Imaging With a Surface Coil NCT00965003 | Stanford University | EARLY_Phase 1 |
| Completed | Nicotine Levels With Response Rates to Radiation Alone or With Chemo In Head & Neck Cancer NCT01084733 | Mahesh Kudrimoti | — |
| Completed | Randomized Trial to Assess the Impact of a Screening Program on Upper Aerodigestive Tract Cancer Mortality in NCT00359645 | Gustave Roussy, Cancer Campus, Grand Paris | Phase 3 |
| Completed | Functional Voice and Speech Outcomes Following Surgical Voice Restorations: A Comparison of Pharyngeal Constru NCT00600223 | Memorial Sloan Kettering Cancer Center | — |
| Completed | Radiotherapy With Cisplatin Versus Radiotherapy With Cetuximab After Induction Chemotherapy for Larynx Preserv NCT00169247 | Groupe Oncologie Radiotherapie Tete et Cou | Phase 2 |
| Completed | Induction CT by Cisplatin, 5FU With or Without Docetaxel in Patients With T3 and T4 Larynx and Hypopharynx Car NCT00169182 | Groupe Oncologie Radiotherapie Tete et Cou | Phase 3 |
| Completed | Patient Selection for Hypoxia Modifying Treatments in Larynx Carcinomas NCT00160095 | Radboud University Medical Center | — |
| Completed | Accelerated Radiotherapy and Concomitant Chemo-radiotherapy in HNSCC NCT00158652 | Groupe Oncologie Radiotherapie Tete et Cou | Phase 3 |
| Completed | Very Intense Radiotherapy-Chemotherapy Regimen in Advanced HNSCC NCT00162708 | Gustave Roussy, Cancer Campus, Grand Paris | Phase 2 / Phase 3 |
| Terminated | Motexafin Gadolinium With Chemotherapy and Radiation Therapy for the Treatment of Advanced Head and Neck Cance NCT00080028 | Pharmacyclics LLC. | Phase 1 |