| Not Yet Recruiting | Intralesional Cryosurgery Alone Versus Combined With 5-FU and Triamcinolone for Keloids NCT07526168 | Assiut University | N/A |
| Completed | Comparison of Intralesional Triamcinolone Acetonide Treatment With Intralesional Verapamil Hydrochloride in Ke NCT07420166 | Muhammad Aamir Latif | N/A |
| Recruiting | Ritlecitinib in Patients With Keloids or Those Undergoing Keloidectomy NCT06373458 | Icahn School of Medicine at Mount Sinai | Phase 2 |
| Recruiting | Effect of Strontium-90 Brachytherapy Combined With Hyperthermia in the Treatment of Keloid NCT06431360 | Nanjing First Hospital, Nanjing Medical University | N/A |
| Not Yet Recruiting | Efficacy and Safety of Fractional CO2 Laser Combined With Intralesional Insulin, Botulinum Toxin or Triamcinol NCT06230146 | Assiut University | Phase 1 / Phase 2 |
| Unknown | Ethosomal Gel Bearing Losartan 5% for Keloid Treatment NCT05893108 | Yuni Eka Anggraini | Phase 1 / Phase 2 |
| Recruiting | Comparing the Effect of siSPARC Microneedle Patch Versus siSPARC+siLR4A Microneedle Patch on Post-surgical Sca NCT06138964 | National Skin Centre | Phase 2 |
| Completed | Comparative Study Between Intralesional Corticosteroid Injection Alone and Combined Intralesional Corticostero NCT07263100 | Somdech Phra Nangchao Sirikit Hospital | N/A |
| Completed | Study to Assess Efficacy and Safety of Dupilumab in the Treatment of Keloids NCT05128383 | Beth Israel Deaconess Medical Center | Phase 2 |
| Enrolling By Invitation | Preoperative Silicone Ointment and Wound Healing NCT05461157 | Yale University | N/A |
| Unknown | Piezoelectric Drived Microneedling in Treating Refractory Skin Diseases NCT05488860 | Xiangya Hospital of Central South University | N/A |
| Completed | Class I Medical Device on Post-surgical Scars NCT05412745 | University of Rome Tor Vergata | N/A |
| Unknown | Bleomycin Jet Injections in Keloids NCT04582305 | Erasmus Medical Center | Phase 4 |
| Completed | Examining the Therapeutic Potential of Botulinum Toxin Type A in the Treatment of Keloids NCT05330078 | University of California, San Diego | EARLY_Phase 1 |
| Completed | Analyse of Diagnosis Value of Keloid on 68Ga- FAPI-04 PET-CT NCT05275699 | Peking Union Medical College Hospital | Phase 1 / Phase 2 |
| Completed | The Effect of Intralesian Injection of Umbilical Cord Mesenchymal Stem Cells, Its Conditioned Medium, and Tria NCT05939817 | Rumah Sakit Pusat Angkatan Darat Gatot Soebroto | Phase 4 |
| Completed | Comparison of Keloid Volume and Symptoms Reduction Between Intralesional Umbilical-Cord Mesenchymal Stem Cells NCT05887804 | Rumah Sakit Pusat Angkatan Darat Gatot Soebroto | Phase 4 |
| Completed | Photobiomodulation and the Intralesional Administration of Corticoid in the Keloid Surgery. NCT04824612 | University of Nove de Julho | N/A |
| Completed | Multimodal Ultrasound Imaging Assessment on Keloid NCT06034587 | Chongqing Medical University | — |
| Completed | Safety and Efficacy of AIV001 on Scar Formation and Keloid Recurrence Following Keloidectomy NCT04827875 | AiViva BioPharma, Inc. | Phase 1 |
| Completed | Dupilumab in the Treatment of Keloids NCT04988022 | Icahn School of Medicine at Mount Sinai | Phase 4 |
| Unknown | Efficacy of Adipose Derived Stromal Vascular Fraction in the Treatment of Keloids NCT04391621 | Makerere University | Phase 2 |
| Completed | A Study for Safety and Efficacy Evaluation of Various Doses of STP705 in Reducing Keloid Recurrence NCT04844840 | Sirnaomics | Phase 2 |
| Completed | Autologous Adipose Derived Stem Cells Transplantation in the Treatment of Keloids. NCT04553159 | Makerere University | Phase 2 |
| Completed | Post-Surgical Injection With Triamcinolone Versus Triamcinolone/Fluorouracil in Treatment of Keloids NCT04710719 | Our Lady of the Lake Hospital | N/A |
| Recruiting | Radiotherapy for Keloids NCT04722263 | Montefiore Medical Center | N/A |
| Unknown | Comparison of the Efficacy of Different Steroids in the Treatment of Abnormal Scars (Keloids, Hypertrophic Sca NCT04593706 | Tel-Aviv Sourasky Medical Center | N/A |
| Unknown | The Safety and Efficacy of Thermo-mechanical System for Fractional Ablation Associated Triamcinolone Acetonide NCT04597060 | Mahidol University | N/A |
| Unknown | Implantation of Mesenchymal Stem Cell, Conditioned Medium, or Triamcinolone Acetonide for Keloid NCT04326959 | PT. Prodia Stem Cell Indonesia | Phase 1 / Phase 2 |
| Completed | RAPA-Keloid Study of Keloid Regression NCT04049552 | The University of Texas Health Science Center at San Antonio | EARLY_Phase 1 |
| Unknown | Clinical Safety and Scar Prevention Study of a Topical Antifibrotic Compound FS2. NCT04186273 | University of British Columbia | Phase 2 |
| Completed | Pilot Study Investigating a Restorative Wound Care Cream Together With Petrolatum on Surgical Excisions NCT04169438 | The Center for Clinical and Cosmetic Research | N/A |
| Completed | Light Emitting Diode-Red Light (LED-RL) Phototherapy for Skin Scarring Prevention NCT03795116 | State University of New York - Downstate Medical Center | Phase 2 |
| Completed | "A Clinical Study Investigating the Effectiveness of OTC Scar-management Modalities" NCT04169490 | The Center for Clinical and Cosmetic Research | N/A |
| Terminated | Imiquimod for Preventing Keloid Recurrence NCT03760250 | University of Pennsylvania | Phase 2 |
| Completed | Pain Outcomes Following Intralesional Corticosteroid Injections NCT03630198 | Vanderbilt University Medical Center | Phase 4 |
| Completed | Efficacy, Safety, and Tolerability of Remlarsen (MRG-201) Following Intradermal Injection in Subjects With a H NCT03601052 | miRagen Therapeutics, Inc. | Phase 2 |
| Completed | Therapy of Scars and Cutis Laxa With Autologous Adipose Derived Mesenchymal Stem Cells NCT03887208 | Medical University of Warsaw | Phase 1 / Phase 2 |
| Unknown | Phase 1 Study of HF-LED-RL in Fitzpatrick Skin Types I to III NCT03433222 | VA Northern California Health Care System | Phase 1 |
| Completed | Compressive Device to Prevent Keloïd Scars Recurrence [SCARWARS] NCT03312166 | Centre Hospitalier Universitaire de Besancon | N/A |
| Completed | Gene Expression and Biomarker Profiling of Keloid Skin NCT03228693 | Northwestern University | N/A |
| Unknown | Restenosis in Coronary Stents And Cutaneous HEaLing NCT04915391 | Fundación para la Investigación Biosanitaria del Principado de Asturias | — |
| Unknown | Efficacy of Intralesional Triamcinolone and 8% Topical Pirfenidone for Treatment of Keloid Scars NCT02823236 | Centro Dermatológico Dr. Ladislao de la Pascua | Phase 3 |
| Unknown | Retrospective Study of Keloid Disorder NCT02923596 | Tirgan, Michael H., M.D. | — |
| Completed | Surgical Excision and Intralesional Steroid Injection for Prevention of Post Caesarean Keloid Recurrence NCT03239964 | Kasr El Aini Hospital | Phase 4 |
| Withdrawn | Comparison of Dual-mode ER:YAG Laser in Patients With Long Keloid/Hypertrophic Scars NCT02546076 | Insel Gruppe AG, University Hospital Bern | Phase 2 |
| Completed | Fractional Laser Assisted Steroid Therapy vs Intralesional Steroids in the Treatment of Keloids NCT02996097 | Johns Hopkins University | N/A |
| Completed | High Fluence Light Emitting Diode-Red Light (LED-RL) in Human Skin NCT02630303 | Jared Jagdeo, MD, MS | Phase 1 |
| Completed | Improving Keloids Using Targeted Ultraviolet-B Irradiation NCT03160053 | Johns Hopkins University | N/A |
| Completed | FS2 Safety and Tolerability Study in Healthy Volunteers NCT02340325 | British Columbia Professional Firefighters' Burn and Wound Healing Laboratory | Phase 1 |
| Completed | Treatment of Keloid Scar by Autologous Platelet Rich Plasma Obtained With RgenKit-BCT NCT02922972 | Regen Lab SA | N/A |
| Completed | A Study Using Fractional Carbon Dioxide and Long Pulsed Neodymium-yttrium Aluminum Garnet Lasers in Treatment NCT03460431 | Cairo University | N/A |
| Completed | A Study to Evaluate the Effectiveness and Safety of RXI-109 on the Outcome of Keloid Excision Surgery in Healt NCT02079168 | RXi Pharmaceuticals, Corp. | Phase 2 |
| Completed | Calcium Electroporation for the Treatment of Keloids NCT01941914 | Herlev Hospital | Phase 1 |
| Completed | Pilot Study of a Novel 532nm KTP Laser for the Treatment of Fresh Surgical Scars NCT01789346 | Cutera Inc. | N/A |
| Terminated | Study of Psycho-Social Impact of Keloid NCT01478243 | Tirgan, Michael H., M.D. | — |
| Terminated | Keloid Tissue Bank NCT01425437 | Tirgan, Michael H., M.D. | — |
| Terminated | Therapeutic Study of Bevacizumab Injection Directly Inside the Keloid Tissue NCT01408953 | Tirgan, Michael H., M.D. | Phase 2 |
| Unknown | Keloid Radiation Registry NCT01457079 | Tirgan, Michael H., M.D. | — |
| Recruiting | Web Based Investigation of Natural History of Keloid Disorder, an Online Survey NCT01423981 | Tirgan, Michael H., M.D. | — |
| Unknown | Epidemiology Study of Keloid NCT01423383 | Tirgan, Michael H., M.D. | — |
| Completed | Evaluation of the Initial Safety and Efficacy of Keloid Lesions Treated With MF-4181 NCT01446770 | Halscion, Inc. | Phase 2 |
| Unknown | Safety and Efficacy of Infrared Diode Laser on Improvement of Scar and Prevention of Recurrence of Excised Kel NCT01158196 | Ekkyo | Phase 3 |
| Completed | Case-control Study on Matrix Metalloproteinase Levels in Tissue in Patients With Keloid Scar NCT01125137 | Henry Ford Health System | N/A |
| Completed | Intralesional Cryotherapy With a Argon Gas Based Device for the Treatment of Keloid and Hypertrophic Scars NCT02063243 | Amsterdam UMC, location VUmc | N/A |
| Recruiting | Genetic Analysis of Keloids NCT01619553 | UConn Health | — |
| Completed | Exploratory Study of the Efficacy and Safety of Juvista 250ng When Administered Following Excision of Ear Lobe NCT00836147 | Renovo | Phase 1 / Phase 2 |
| Completed | Prospective Evaluation of the Use of Intralesional Cryotherapy for Treatment of Keloid and Hypertrophic Scars NCT01994616 | Amsterdam UMC, location VUmc | — |
| Completed | Safety of Juvista When Administered Following Excision of Ear Lobe Keloids NCT00710333 | Renovo | Phase 1 / Phase 2 |
| Completed | A Pilot Study of Apligraf for the Treatment and Prevention of Recurrence of Excised Keloids NCT00587587 | Organogenesis | Phase 1 / Phase 2 |
| Terminated | A Randomized Clinical Study Comparing Two Closure Techniques of Excised Keloids NCT00519493 | University of Miami | N/A |
| Completed | Trial of Juvista (Avotermin) Following Removal of Ear Lobe Keloid Scars NCT00469235 | Renovo | Phase 1 / Phase 2 |
| Unknown | Influence of a Silicone Gel (Dermatix®) on Thoracic Scar Formation After Harvesting of Autologous Rib Cartilag NCT00565552 | University Hospital Schleswig-Holstein | N/A |
| Completed | A Randomized Comparative Study Evaluating the Tolerability and Efficacy of Two Topical Therapies for the Treat NCT00754247 | University of Miami | Phase 4 |
| Completed | High Dose Rate Brachytherapy for Treatment of Keloids NCT02005055 | Amsterdam UMC, location VUmc | — |
| Completed | Ultraviolet B (UVB) Light Therapy in the Treatment of Skin Conditions With Altered Dermal Matrix NCT00129428 | University of Michigan | Phase 1 / Phase 2 |
| Completed | Genetic Analysis of Familial Keloids NCT00008502 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | — |
| Terminated | UVA1 Light for Scleroderma and Similar Conditions NCT00476697 | University of Michigan | N/A |