| Not Yet Recruiting | Efficacy and Safety of FMT for the Treatment of IBS-D and Mental Health Comorbidity in Young Adults NCT06297421 | Shenzhen Hospital of Southern Medical University | Phase 2 |
| Completed | The Effect of Dietary Supplementation on Intestinal Barrier Function in IBS-D NCT06543498 | Dr Anthony Hobson | N/A |
| Recruiting | B.Subtilis Attenuate Symptoms in Diarrhea-predominant Irritable Bowel Syndrome by Increasing Hypoxanthine Bios NCT06612411 | Jinling Hospital, China | EARLY_Phase 1 |
| Recruiting | A Study to Evaluate the Efficacy and Safety of Live SK08 Powder in Patients With IBS-D NCT06247046 | Guangzhou Zhiyi Biotechnology Co., Ltd. | Phase 3 |
| Enrolling By Invitation | Effect of Consuming a Nutraceutical Composition on Signs and Symptoms in Adult Patients With Irritable Bowel S NCT07103772 | Universidad Autonoma de Nuevo Leon | N/A |
| Completed | Evaluation of Butyrate and Palmitoylethanolamide in IBS Patients (B/P3_1) NCT06432569 | University of Padova | N/A |
| Terminated | Study of the Research Medicine CIN-103 in Adults With Irritable Bowel Syndrome With Predominant Diarrhea (IBS- NCT06153420 | CinPhloro Pharma, LLC | Phase 2 |
| Completed | Safety and Efficacy of a Probiotic Supplement in IBS-D NCT05754177 | The Archer-Daniels-Midland Company | N/A |
| Completed | Self- Administered Acupressure for Diarrhea Predominant Irritable Bowel Syndrome NCT05702255 | Alexandria University | N/A |
| Unknown | Efficacy and Safety of DT01 Tablets in Patients With Irritable Bowel Syndrome With Diarrhea NCT05719896 | Centre of Clinical Pharmacology, Hanoi Medical University | Phase 2 |
| Completed | To Compare the Efficacy of Drugs in Combination for Treating Irritable Bowel Syndrome Associated With Diarrhea NCT05867550 | Bahria University | Phase 4 |
| Unknown | Personalized Dietary Intervention Based on Microbiome Analysis vs FODMAP Diet for Irritable Bowel Syndrome NCT05646186 | Istanbul Medipol University Hospital | N/A |
| Completed | Probiotics as Adjuvant Therapy in the Management of Irritable Bowel Syndrome NCT05523427 | University of Mosul | N/A |
| Withdrawn | Comparing the Efficacy of Nitazoxanide Versus Rifaximin in Adult Patients With Irritable Bowel Syndrome Withou NCT05453916 | Sadat City University | Phase 1 / Phase 2 |
| Completed | Evaluating the Safety and Efficacy of the Probiotic Bifidobacterium Longum ES1 and the Post Biotic Heat-treate NCT05339243 | Vedic Lifesciences Pvt. Ltd. | N/A |
| Completed | Aldafermin (NGM282) for Chronic Diarrhea Due to Bile Acid Malabsorption (BAM) NCT05130047 | Michael Camilleri, MD | Phase 2 |
| Completed | GI Permeability Change in Response to Aquamin® NCT04855799 | James Varani | Phase 2 |
| Unknown | Study on the Molecular Mechanism of Diarrhea-predominant Irritable Bowel Syndrome With Anxiety and Depression NCT05311293 | Tang-Du Hospital | — |
| Completed | To Study the Efficacy and Safety of L. Plantarum UALp-05TM in Diarrhea- Predominant-irritable Bowel Syndrome NCT04950296 | Vedic Lifesciences Pvt. Ltd. | N/A |
| Completed | The Role of Fiber in the Prevention and Treatment of Fecal Incontinence NCT04806386 | Massachusetts General Hospital | N/A |
| Unknown | Intestinal Permeability and Intestinal Microbiota in Irritable Bowel Syndrome NCT05379036 | I.M. Sechenov First Moscow State Medical University | Phase 4 |
| Completed | Faecal Microbiota Transplantation in Irritable Bowel Syndrome NCT04899869 | Thomayer University Hospital | N/A |
| Completed | The Effects of Carbohydrates in Irritable Bowel Syndrome NCT04830410 | Sahlgrenska University Hospital | N/A |
| Completed | Efficacy and Safety of Rifaximin With NAC in IBS-D NCT04557215 | Cedars-Sinai Medical Center | Phase 1 / Phase 2 |
| Completed | Clinical Study to Evaluate the IBS Symptoms Improving Effect and Safety of GTB1 NCT05277428 | Amorepacific Corporation | N/A |
| Completed | Efficacy and Safety of Changkang Granule in the Treatment of Diarrhea-predominant Irritable Bowel Syndrome (IB NCT04492787 | Tasly Pharmaceutical Group Co., Ltd | Phase 2 |
| Withdrawn | A Non-Interventional Pilot Study to Explore the Role of Gut Flora in IBS NCT04214470 | ProgenaBiome | — |
| Completed | Hydrogen Breath Test an Instrument to Predict Rifaximin-Response in Irritable Bowel Syndrome Predominant Diarr NCT03729271 | University of Michigan | Phase 4 |
| Completed | A Comparison of the Effects of ORP-101 Versus Placebo in Adult Patients With Irritable Bowel Syndrome With Dia NCT04129619 | OrphoMed, Inc. | Phase 2 |
| Completed | Multi Strain Probiotic Preparation in Patients With Irritable Bowel Syndrome NCT04662957 | Children's Memorial Health Institute, Poland | N/A |
| Completed | A Mediterranean Approach to Low FODMAP Diet (MED-LFD) for Managing IBS Symptoms NCT03997708 | Attikon Hospital | N/A |
| Completed | Lactobacillus LB as Treatment for Irritable Bowel Syndrome With Predominance of Diarrhea (IBS-D) NCT04053790 | Hospital General de Mexico | Phase 4 |
| Completed | Interest of Pan Capsule in Symptomatic Patients Suspected of Irritable Bowel Syndrome Requiring Colonoscopy NCT03806959 | Hospital Avicenne | N/A |
| Completed | Changes in Microbiota and Metabolomic Profile Between Rifaximin Responders and Non-responders In Diarrhoea-Pre NCT03557788 | National University Hospital, Singapore | Phase 4 |
| Completed | Eluxadoline Bile Acid Malabsorption (BAM) Study NCT03441581 | Allergan | Phase 4 |
| Completed | Efficacy and Safety of a Food Supplement With Standardized Menthol, Limonene, and Gingerol Content in Patients NCT04484467 | Federal Stare Budgetary Scientific Institution, Mental Health Research Center | N/A |
| Completed | Trial to Understand Efficacy of Colesevelam in Diarrhea Predominant IBS Patients With Bile Acid Malabsorption NCT03270085 | Mayo Clinic | Phase 2 |
| Unknown | Effect of FODMAPs on Mucosal Inflammation in IBS Patients NCT03221790 | Queen's University | N/A |
| Completed | FODMAP Reintroduction in Irritable Bowel Syndrome NCT03245645 | University of California, Los Angeles | N/A |
| Completed | Efficacy of Eluxadoline in the Treatment of Irritable Bowel Syndrome With Diarrhea in Patients With Inadequate NCT02959983 | Allergan | Phase 4 |
| Completed | Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial of BEKINDA (Ondansetron 12 mg Bimodal Release Table NCT02757105 | RedHill Biopharma Limited | Phase 2 |
| Completed | The Efficacy of PX0612 In The Treatment Of Irritable Bowel Syndrome NCT02431533 | Pharmabiotix Inc | N/A |
| Withdrawn | 12-Week Efficacy and Safety Study of Ibodutant in Women With Irritable Bowel Syndrome With Diarrhea (IBS-D) NCT02320318 | Menarini Group | Phase 3 |
| Completed | 12-Week Efficacy and Safety Study of Ibodutant in Women With Irritable Bowel Syndrome With Diarrhea (IBS-D) NCT02107196 | Menarini Group | Phase 3 |
| Terminated | 52-Week Efficacy and Safety Study of Ibodutant in Women With Irritable Bowel Syndrome With Diarrhea (IBS-D) NCT02120027 | Menarini Group | Phase 3 |
| Completed | Therapeutic Effect of Chang'an I Recipe on Irritable Bowel Syndrome With Diarrhea NCT02822118 | Xiyuan Hospital of China Academy of Chinese Medical Sciences | Phase 1 / Phase 2 |
| Completed | Irritable Bowel Syndrome With Diarrhea (IBS-D) Rifaximin Re-Treatment Study NCT01543178 | Bausch Health Americas, Inc. | Phase 3 |
| Completed | Ibodutant for Relief of Irritable Bowel Syndrome With Diarrhoea (IBS-D) NCT01303224 | Menarini Group | Phase 2 |
| Completed | Mesalamine Granules for Irritable Bowel Syndrome (IBS) With Diarrhea NCT01177410 | Bausch Health Americas, Inc. | Phase 2 |
| Completed | Post-Infectious Irritable Bowel Syndrome (PI-IBS) NCT01497847 | KU Leuven | — |
| Completed | Efficacy Study of Rezular (Arverapamil) in the Treatment of Irritable Bowel Syndrome With Diarrhea (IBS-D) NCT00552565 | AGI Therapeutics, Inc. | Phase 3 |