| Not Yet Recruiting | Rifampin-free Regimen Versus Rifampin-containing Regimen in the Treatment of Staphylococcal Prosthetic Valve E NCT07345325 | Nantes University Hospital | Phase 3 |
| Not Yet Recruiting | Belgian Infective Endocarditis Registry NCT06745440 | Universitair Ziekenhuis Brussel | — |
| Not Yet Recruiting | Evaluation of the Impact of a Patient Education Protocol on the Quality of 18F-FDG PET Imaging Indicated for I NCT07029295 | Assistance Publique - Hôpitaux de Paris | N/A |
| Not Yet Recruiting | Oritavancin for CIED Infections With MDR Gram-positive Cocci NCT07013552 | Medical University of Silesia | N/A |
| Recruiting | Echocardiography Versus no Echocardiography in S. Aureus Bacteraemia and VIRSTA Score < 3 NCT06457386 | Assistance Publique - Hôpitaux de Paris | N/A |
| Terminated | Combined Rehabilitation and Nutritional Support vs. Standard Care in In-Hospital Endocarditis Treatment NCT06563609 | Johannes Grand | N/A |
| Recruiting | CBCT vs OPT on the Oral Health Status at 12 Months of Patients Hospitalized for Infective Endocarditis. NCT06269679 | Nantes University Hospital | N/A |
| Recruiting | Contribution of PET/CT With Gallium 68 Citrate (68Ga-PET/CT) for the Diagnosis of Prosthetic Valve Infective E NCT05446376 | University Hospital, Bordeaux | Phase 2 |
| Not Yet Recruiting | Management of Anemia in Patients with EndocaRditis Infectious Candidates for Cardiac Surgery: the AMERICA Stud NCT06583902 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Recruiting | Healthrelated Quality of Life and Experiences of a Heart Rehabilitation Programme After Care for Infective End NCT06704048 | Region Halland | N/A |
| Recruiting | Prognosis of Patients With Infective Endocarditis and Risk Stratification Value of Biomarkers (ENDEAVOR） NCT05965362 | First Affiliated Hospital Xi'an Jiaotong University | — |
| Recruiting | The Incidence, Clinical Characteristics and Outcome of Infective Endocarditis Among Intravenous Drug Abusers V NCT06194409 | Assiut University | — |
| Unknown | The Predictive Value of Lubricin in Patients With Infective Endocarditis NCT06266741 | Aydin Adnan Menderes University | — |
| Recruiting | INfectious DIsease REgistry BIObank NCT06418048 | IRCCS San Raffaele | — |
| Active Not Recruiting | The Epidemiology Change From 2006 to 2022 of Infective Endocarditis in Taiwan NCT07156292 | National Taiwan University Hospital | — |
| Unknown | Evaluation of the Usefulness of Echocardiography in Patients With Staphylococcus Aureus Bacteremia (ET-AUREUS NCT05862025 | Puerta de Hierro University Hospital | N/A |
| Not Yet Recruiting | SURgical Registry of ENDocarditis EuRope NCT05563662 | University Hospital, Essen | — |
| Recruiting | Reducing Risk for Infective Endocarditis NCT05721781 | Wake Forest University Health Sciences | N/A |
| Active Not Recruiting | Accuracy of Metagenomic Blood Sampling to Identify Pathogen in Infective Endocarditis Patients NCT06309680 | Queen Mary University of London | — |
| Completed | Incidence of Infective Endocarditis in End Stage Renal Disease Patients on Hemodialysis by Transesophageal Ech NCT05692089 | Assiut University | — |
| Completed | Early Feasibility Study of Somatostatin Receptors PET Imaging for the Diagnosis of Infective Endocarditis NCT05183555 | Central Hospital, Nancy, France | Phase 2 |
| Completed | Infective Endocarditis in Percutaneous Pulmonary Revalvulation: Comparison Between Melody and Sapien Valves NCT06186258 | Centre Chirurgical Marie Lannelongue | — |
| Unknown | Transcatheter Pulmonary Valve Implantation With SAPIEN 3 Valve NCT05264181 | Centre Chirurgical Marie Lannelongue | — |
| Recruiting | Impact of FDG-PET/CT on Management of Patients with Native Valve Infective Endocarditis NCT04792281 | Montreal Heart Institute | — |
| Recruiting | Betalactam Pharmacokinetics in Endocarditis Patients NCT04647331 | Uppsala University | — |
| Unknown | Partial Oral Antimicrobials to Treat Infective Endocarditis in People Who Inject Drugs NCT04544306 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Completed | Personalized Medicine in Patients With Infective Endocarditis NCT04838938 | Fundación para la Investigación Biosanitaria del Principado de Asturias | — |
| Recruiting | Prospective Cohort Study of Patients With Infective Endocarditis at Pitié-Salpêtrière Hospital NCT04992923 | Assistance Publique - Hôpitaux de Paris | — |
| Unknown | NExt-Generation Sequencing and Cell Culture-based Characterization of S. Aureus in Infective Endocarditis NCT04257292 | Jena University Hospital | — |
| Unknown | Predisposition to Infectious Endocarditis NCT03979261 | Assistance Publique Hopitaux De Marseille | — |
| Enrolling By Invitation | Study of Leukocyte Immunophenotype and the Lipid Transport System as Predictive Biomarkers of Severe Bacterial NCT04178915 | The Republican Research and Practical Center for Epidemiology and Microbiology | — |
| Completed | Does Whole Blood Adsorber During CPB Reduce Vasoactive Drugs Postoperatively in Endocarditis Patients Undergoi NCT03945708 | Emma Hansson | N/A |
| Recruiting | Barts Endocarditis Research Registry NCT06434012 | Queen Mary University of London | — |
| Unknown | Vancomycin, Gentamycin in Infective Endocarditis NCT03688659 | Assiut University | N/A |
| Unknown | Detection of the Most Common Microorganism of Infective Endocarditis in Assiut University Hospital NCT03487653 | Safaa Samir | — |
| Completed | Characterization of RadiOlabeled Tracer Uptake Pattern in Noninfected Transcatheter Aortic Valves. NCT03683355 | Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec | — |
| Completed | Cardiac Surgery Peer Recovery Support Program NCT03590106 | University of Rochester | N/A |
| Completed | PET/MR Imaging In Patients With Infective Endocarditis NCT03626571 | University of Edinburgh | — |
| Completed | Evaluation of a Metabolic Preparation by a Low-carbohydrate Diet as Atkins-diet to Help in Detecting Infective NCT03465098 | Central Hospital, Nancy, France | N/A |
| Completed | Hemoadsorption for Prevention of Vasodilatory Shock in Cardiac Surgery Patients With Infective Endocarditis NCT03266302 | Jena University Hospital | N/A |
| Completed | PRetest prObability of Infectious ENDOCARDITIS for Appropriate Criteria Regarding Transesophageal ECHOcardiogr NCT03365193 | University Hospital, Essen | — |
| Completed | Impact of the Blood Culture Technique on the Diagnosis of Infective Endocarditis NCT03153384 | Central Hospital, Nancy, France | — |
| Completed | Clinical Metagenomics of Infective Endocarditis NCT03199287 | University Hospital, Geneva | — |
| Unknown | Effect of Dexmedetomidine on Postoperative Renal Function in Infective Endocarditis Patients Undergoing Open H NCT02698930 | Yonsei University | N/A |
| Completed | Inflammatory Mediator Profiles During Heart Valve Replacement Surgery NCT02727413 | Jena University Hospital | — |
| Completed | Oral Switch During Treatment of Left-sided Endocarditis Due to Multi-susceptible Streptococcus NCT02701595 | University Hospital, Tours | Phase 3 |
| Completed | Oral Switch During Treatment of Left-sided Endocarditis Due to Multi-susceptible Staphylococcus NCT02701608 | University Hospital, Tours | Phase 3 |
| Completed | Retrospective Analysis of Nephrotoxicity During Daptomycin Versus Vancomycin Treatments in High Risk Patients NCT03961503 | University Hospital, Montpellier | — |
| Completed | Evaluation of Systemic Microvascular Endothelial Dysfunction in Patients Presenting With Infective Endocarditi NCT02940340 | National Institute of Cardiology, Laranjeiras, Brazil | — |
| Completed | 18-FDG PET/CT Imaging and Clinical Decisions in Infective Endocarditis NCT02287792 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Infective Endocarditis in the Elderly NCT02910856 | Central Hospital, Nancy, France | — |
| Unknown | PET CT in Suspected CIED Infection, a Pilot Study - PET Guidance I NCT02196753 | National Institute of Cardiology, Warsaw, Poland | — |
| Completed | Research Interest Antiphospholipid in Predicting Embolic Risk During Infective Endocarditis NCT02887079 | Central Hospital, Nancy, France | — |
| Unknown | Beta-lactam Pharmacokinetics in Patients With Infective Endocarditis NCT02033421 | University of Aarhus | — |
| Unknown | Endocarditis Registry of the University Hospital of Cologne (ER-UHC) NCT02388893 | University of Cologne | — |
| Completed | Coagulation and Fibrinolysis as Virulence Factors for Invasive Staphylococcus Aureus and Streptococcus Infecti NCT01731483 | Universitaire Ziekenhuizen KU Leuven | — |
| Completed | Early Clinical, Laboratory and Microbiological Predictors of Treatment Outcomes in Infective Endocaridtis NCT02466139 | Government Medical College, Kozhikode | — |
| Completed | Infective Endocarditis in Developing Countries, a Prospective, Observational, Multicentre Study NCT02128139 | Institut National de la Santé Et de la Recherche Médicale, France | — |
| Completed | CopenHeart IE - Integrated Rehabilitation of Patients Treated for Infective Endocarditis NCT01512615 | Rigshospitalet, Denmark | N/A |
| Completed | Fosfomycin Plus Imipenem for Treatment of Infective Endocarditis NCT00871104 | Juan A. Arnaiz | Phase 4 |
| Terminated | Phase 4 Efficacy and Safety Study of Cubicin® With and Without Combination Therapy in S. Aureus Infective Endo NCT00638157 | Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | Phase 4 |
| Terminated | Phase 2 Study of Safety, Efficacy, and Pharmacokinetics of Higher Doses of Daptomycin and Vancomycin in MRSA B NCT00695903 | Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | Phase 2 |
| Completed | Impact of Endothelial Cell Activation and Modifications of Haemostasis Induced by Infective Endocarditis on th NCT00947817 | Assistance Publique Hopitaux De Marseille | N/A |
| Completed | Hygiene and Bucco-dental Status of Patients With Oral Streptococcal Endocarditis NCT03612245 | Centre Hospitalier Universitaire de Besancon | — |
| Completed | Characteristics of Infective Endocarditis in East China NCT04977518 | Second Affiliated Hospital, School of Medicine, Zhejiang University | — |
| Completed | Evolution of the Profile of Infectious Endocarditis in France in 2008 (EI2008) NCT03295045 | Centre Hospitalier Universitaire de Besancon | — |
| Unknown | Cardiac Computarized Tomography in Infective Endocarditis NCT00550823 | Tel-Aviv Sourasky Medical Center | N/A |
| Unknown | Autoantibodies and Clinical Symptoms in Infective Endocarditis Patients NCT00562653 | Tel-Aviv Sourasky Medical Center | — |
| Unknown | Rationale, Design and Methods for the Early Surgery in Infective Endocarditis Study (ENDOVAL) NCT00624091 | Instituto de Ciencias del Corazon | Phase 4 |
| Enrolling By Invitation | Infective Endocarditis Surgery Using Conventional Prosthetic Valves Versus Cryopreserved Aortic Homograft NCT05253469 | Centre Cardiologique du Nord | — |
| Recruiting | French National Observatory on Infective Endocarditis NCT03272724 | Central Hospital, Nancy, France | — |