NCT02128139

Infective Endocarditis in Developing Countries, a Prospective, Observational, Multicentre Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 300 (actual)
• Sponsor: Institut National de la Santé Et de la Recherche Médicale, France · Other Government
• Sex: All
• Age: 1 Year
• Healthy volunteers: Not accepted

Summary

Introduction. Comprehensive data on infective endocarditis in developing countries are scarce. Objectives: Description of the characteristics (clinical and microbiological) and assessment of the outcomes of infective endocarditis in low-income countries. Methods : Prospective, Observational, Multicentre study. Inclusion criteria: patients aged over 1 year fulfilling the modified Duke criteria for infective endocarditis. Exclusion criteria: patient included during a previous infective endocarditis episode. Outcomes measures: Mortality at 6 months follow-up; mortality at 1 month follow-up; access to antibiotic treatment (modalities and duration), hospital length of stay and reason for discharge, and cardiac surgery when indicated. Duration: One year (June 2014- June 2015)

Conditions

• Infective Endocarditis

Timeline

• Start date: 2012-04-01
• Primary completion: 2015-04-01
• Completion: 2015-10-01
• First posted: 2014-05-01
• Last updated: 2025-05-22

Locations

6 sites across 5 countries: Fiji, Laos, Mozambique, Senegal, Uganda