| Recruiting | Antihypertensive Mechanisms of Minocycline in Resistant Hypertension NCT06246396 | University of Florida | Phase 4 |
| Recruiting | Baroloop Multicenter Trial (Baroloop MCT) NCT06518915 | neuroloop GmbH | N/A |
| Recruiting | A Preventive, Multidisciplinary Primary Care Intervention Organized Around a Therapeutic Garden: Acceptability NCT06646601 | Assistance Publique Hopitaux De Marseille | N/A |
| Active Not Recruiting | RADIANCE Continued Access Protocol NCT05017935 | ReCor Medical, Inc. | N/A |
| Completed | Use of Automated Office Blood Pressure Monitoring NCT05395403 | University of Alabama at Birmingham | N/A |
| Terminated | UK Registry for Baroreflex Activation Therapy NCT03730519 | Queen Mary University of London | N/A |
| Withdrawn | MANP in African Americans With Hypertension NCT04542681 | Mayo Clinic | Phase 1 |
| Unknown | Moderato System in Patients With Hypertension NCT03757377 | BackBeat Medical Inc | N/A |
| Completed | High Prevalence of Secondary Arterial Hypertension (HIPRESH) with Prospective Systematic Screening in a Cohort NCT06664255 | University Hospital Padova | — |
| Unknown | Health Coaching Based Treatment Versus Usual Treatment of Systemic Arterial Hypertension and Comorbidities NCT03046680 | Universidade Federal de Goias | N/A |
| Unknown | Moderato System: A Double-Blind Randomized Trial Ver 1.1 NCT02837445 | BackBeat Medical Inc | N/A |
| Unknown | A Study to Evaluate Safety and Efficacy of the Redy™ Renal Denervation System in the Treatment of Patients Wit NCT02690909 | Renal Dynamics GmbH | N/A |
| Terminated | Chemical Renal Ethanol Sympatholysis Under CT Guidance Use for the Control of Therapy-Resistant Hypertension NCT02653222 | University Hospital, Grenoble | Phase 2 |
| Completed | Peripheral Chemoreflex/Arterial Baroreflex Interaction in Patients With Electrical Carotid Sinus Stimulation NCT02587533 | Hannover Medical School | N/A |
| Unknown | The Use of Ambulatory Blood Pressure Monitors to Assess Angiotensin Converting Enzyme Inhibitors NCT02623036 | Memorial Health University Medical Center | Phase 1 |
| Completed | Sequential Nephron Blockade vs. Dual Blockade Renin-angiotensin System + Bisoprolol in Resistant Arterial Hype NCT02832973 | Sao Jose do Rio Preto Medical School | Phase 4 |
| Terminated | Renal Artery Stenting in Patients With Documented Resistant Hypertension and Atherosclerotic Renal Artery Sten NCT02539810 | Assistance Publique - Hôpitaux de Paris | Phase 4 |
| Unknown | CPAP Effect on Blood Pressure and Arterial Stiffness in Obstructive Sleep Apnea Patients With Resistant Hypert NCT02385864 | University Hospital, Grenoble | — |
| Terminated | How to Test Success of a Renal Denervation NCT02559882 | University of Zurich | — |
| Recruiting | Physical Activity Program for Reducing Blood Pressure in Sleep Apnea Patients With Resistant Hypertension NCT02057783 | AGIR à Dom | N/A |
| Unknown | Safety and Efficacy Study of Extracorporeal Shockwave Therapy in the Treatment of Patients With Resistant Hype NCT02042066 | Medispec | Phase 1 |
| Unknown | Medication Adherence and "True" Resistance in Patients With Resistant Hypertension NCT02128386 | Charite University, Berlin, Germany | — |
| Completed | The Use of Educational Technology in Improving Adherence Therapy NCT03324386 | University of Sao Paulo General Hospital | N/A |
| Unknown | Effect Baroreflex Activation Therapy on the Carotid Body NCT02210923 | Maastricht University Medical Center | — |
| Unknown | Continued Safety and Performance of the TIVUS System NCT01835535 | Cardiosonic | Phase 2 / Phase 3 |
| Completed | Addition of Homeopathy in Patients With Resistant Arterial Hypertension NCT02124473 | Macmillan Research Group UK | Phase 2 |
| Completed | Causal Inference Research of Resistant Hypertension Treatment With Chinese Approach in a Cohort Study NCT01904695 | China Academy of Chinese Medical Sciences | EARLY_Phase 1 |
| Completed | Reintervention-study After Previous Renal Denervation in Non-responding Patients With Severe Hypertension NCT01834118 | Cardiovascular Center Frankfurt | — |
| Completed | Renal Sympathetic Denervation and Potential Effects on Glucose Metabolism and Cardiovascular Risk-Factors NCT01630928 | University Hospital of North Norway | N/A |
| Completed | Safety and Performance Study of the Moderato System NCT02282033 | BackBeat Medical Inc | N/A |
| Completed | Distal Renal Denervation NCT02667912 | Tomsk National Research Medical Center of the Russian Academy of Sciences | N/A |
| Unknown | Effect of Renal Sympathetic Denervation on Resistant Hypertension and Cardiovascular Hemodynamic in Comparison NCT01673516 | Oslo University Hospital | Phase 2 |
| Unknown | The Diagnosis and Treatment of Resistant Hypertension, the Prevalence and the Prognosis NCT01703780 | Chinese Academy of Medical Sciences, Fuwai Hospital | — |
| Completed | Rapid Renal Sympathetic Denervation for Resistant Hypertension NCT01520506 | Medtronic Endovascular | N/A |
| Completed | Renal Denervation in Hypertension NCT01570777 | Assistance Publique - Hôpitaux de Paris | Phase 4 |
| Unknown | Resistant Hypertension and Physical Activity Performed in a Heated Pool NCT01863082 | University of Sao Paulo | N/A |
| Completed | Efficacy of Spironolactone in Cameroonian Diabetic Patients With Resistant Hypertension NCT02426099 | Sobngwi Eugene | Phase 4 |
| Completed | Autonomic Dysfunction in Resistant Hypertension NCT01833429 | University of Campinas, Brazil | — |
| Completed | Full Length Versus Proximal Renal Arteries Ablation NCT01848275 | The Second Affiliated Hospital of Chongqing Medical University | N/A |
| Completed | Combined Treatment of Resistant Hypertension and Atrial Fibrillation NCT01117025 | Meshalkin Research Institute of Pathology of Circulation | Phase 2 |
| Completed | The Effect of Spironolactone on Blood Pressure in Type-2 Diabetics With Resistant Hypertension NCT01062763 | Ib Abildgaard Jacobsen | Phase 3 |
| Unknown | Monotherapy Versus Dual Therapy for Initial Treatment for Hypertension NCT00994617 | University of Cambridge | Phase 4 |
| Completed | Prevalence of Primary Aldosteronism in Patients With Resistant Hypertension in China NCT01459042 | Shanghai Jiao Tong University School of Medicine | — |
| Unknown | Optimum Treatment for Drug-Resistant Hypertension NCT02369081 | University of Cambridge | Phase 4 |
| Completed | Renin-angiotensin-aldosterone System Polymorphisms in Resistant Hypertension and Adverse Cardiovascular Events NCT01173029 | Universidade Gama Filho | — |