Trials / Terminated
TerminatedNCT02653222
Chemical Renal Ethanol Sympatholysis Under CT Guidance Use for the Control of Therapy-Resistant Hypertension
Feasibility Study of Perivascular Computer Tomography-guided Ethanol Sympatholysis for the Treatment of Therapy-resistant Arterial Hypertension
- Status
- Terminated
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 2 (actual)
- Sponsor
- University Hospital, Grenoble · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
In this study the investigators are going to assess the feasibility of this innovate technique of renal sympathetic denervation by translumbar access under ct-guidance. To limit the potential impact on the kidney, the investigators chose a population of chronic renal failure patients on dialysis or renal transplant (with native kidneys still present) and having resistant treatment hypertension despite antihypertensive combination therapy well conducted. The investigators expect to obtain a decrease of the blood pressure at the 24-hours ambulatory blood pressure monitoring (ABPM) one month after the sympathetic denervation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Renal sympathicolysis | |
| PROCEDURE | Ambulatory Blood Pressure Monitoring | 1 month before and after surgery the patient will have an ABPM over 24h |
| RADIATION | Magnetic Resonance Angiography | 1 month before and after surgery the patient will have a MRA |
| BIOLOGICAL | Blood test | complete blood count, blood platelets, coagulation profile, irregular agglutinins search |
Timeline
- Start date
- 2016-02-01
- Primary completion
- 2018-02-01
- Completion
- 2018-02-01
- First posted
- 2016-01-12
- Last updated
- 2018-05-09
Locations
2 sites across 1 country: France
Source: ClinicalTrials.gov record NCT02653222. Inclusion in this directory is not an endorsement.