NCT01833429

Autonomic Dysfunction in Resistant Hypertension

Circadian Autonomic Disturbances in Resistant Hypertension With and Without White-coat Phenomenon

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 44 (actual)
• Sponsor: University of Campinas, Brazil · Academic / Other
• Sex: All
• Age: 30 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The contribution of this study is the unedited evaluation of the circadian autonomic profiles of resistant hypertension with and without white-coat response.

Detailed description

All patients were submitted to office blood pressure measurement, Ambulatory blood pressure monitoring and 24-hour Holter monitoring. Baseline blood samples for the measurement of glycemia (mg/dL), total cholesterol (mg/dL), LDL cholesterol (mg/dL), triglycerides (mg/dL), creatinine (mg/dL), serum uric acid, serum sodium, serum potassium, plasma aldosterone concentration (PAC) and plasma renin activity (PRA) were collected at 08:00 after overnight fasting.

Conditions

• Hypertension, Resistant to Conventional Therapy

Timeline

• Start date: 2011-09-01
• Primary completion: 2012-11-01
• Completion: 2012-12-01
• First posted: 2013-04-16
• Last updated: 2013-04-16

Locations

1 site across 1 country: Brazil