| Withdrawn | Inhibiting GABA Transaminase to Relieve Obesity Induced Hyperinsulinemia and Insulin Resistance NCT04062890 | University of Arizona | Phase 2 |
| Recruiting | Understanding Beta Cell Disorders Through the Study of Rare Genotypes (ENDURE) NCT06478121 | University of Exeter | — |
| Recruiting | Study to Evaluate Biomarkers and Safety of Dapagliflozin Concomitant with Neoadjuvant Therapy NCT05989347 | Yale University | Phase 1 |
| Recruiting | Cardiovascular and Endothelial Markers During OGTT Before and at Six and Twelve Months Post-treatment in Women NCT06889454 | Attikon Hospital | — |
| Recruiting | Fasting Insulin and HOMA-IR by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis NCT05950282 | Lilli Health | — |
| Recruiting | Acute Microbial Switch NCT05764200 | Maastricht University Medical Center | N/A |
| Recruiting | Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-Risk for Type 2 Diabetes NCT05543083 | Colorado State University | N/A |
| Terminated | Continuous Glucose Monitoring in Neonatal Hyperinsulinism NCT06363929 | MemorialCare Health System | — |
| Recruiting | A Pilot Study of Monitoring Insulin Levels and Treating Hyperinsulinemia and Hyperglycemia With Pioglitazone i NCT05753657 | Rambam Health Care Campus | EARLY_Phase 1 |
| Completed | Link Between the Peripheral Mononuclear Cells' Capacity to Induce Insulin Resistance and Hyperinsulinemia NCT05329337 | Centre Hospitalier Universitaire de Nīmes | N/A |
| Completed | NUTRACORE, Glycaemic Index and Appetite NCT05528874 | Azienda Ospedaliero Universitaria Maggiore della Carita | N/A |
| Recruiting | Assessment of Pancreatic Beta Cell Mass and Function by Positron Emission Tomography Imaging in Human Diabetes NCT05662189 | Azienda Ospedaliero-Universitaria di Parma | N/A |
| Unknown | Effect of Hibiscus Sabdariffa Beverage NCT05774613 | Instituto Tecnológico y de Estudios Superiores de Occidente | N/A |
| Unknown | Effects Of Combined Cryolipolysis And High Intensity Interval Training On Insulin Resistance And Body Composit NCT04744896 | Cairo University | N/A |
| Recruiting | Utility of 18FDOPA PET/MRI for Focal Hyperinsulinism NCT05088798 | Washington University School of Medicine | Phase 2 |
| Completed | Bionic Pancreas in Children With Hyperinsulinism and Post-Pancreatectomy Diabetes NCT03303196 | Children's Hospital of Philadelphia | N/A |
| Completed | The Effects of Interrupting Prolonged Sitting With Intermittent Exercise on Postprandial Lipemia NCT03856606 | University of Texas at Austin | N/A |
| Withdrawn | Pasireotide in Hyperinsulinemic Hypoglycemia NCT03053284 | Montefiore Medical Center | Phase 2 |
| Completed | To Compare the Effects of Non-nutritive Sweeteners Intake in Woman With Insulin Resistance NCT04327245 | University of Chile | N/A |
| Completed | Impact of Meal Order on Postprandial Cardiometabolic Risk Markers NCT03358745 | Lund University | N/A |
| Withdrawn | Sirolimus for the Treatment of Hyperinsulinism NCT02524639 | Children's Hospital of Philadelphia | Phase 1 / Phase 2 |
| Completed | Effect of Meal Frequency on Glycemic Control of People at High Risk or Diagnosed With Diabetes NCT02248272 | Meropi Kontogianni | N/A |
| Completed | Whole Body 111In-exendin-4 Imaging Study in Insulinoma Patients NCT00937079 | University Hospital, Basel, Switzerland | — |
| Completed | Utility of [F-18] fluoroDOPA for Neonatal Hyperinsulinism NCT00674440 | Children's Hospital of Philadelphia | Phase 2 |
| Completed | Diazoxide-Mediated Insulin Suppression in Hyperinsulinemic Obese Men NCT00151684 | Rijnstate Hospital | Phase 2 |
| Completed | Genomewide Search for Loci Underlying Metabolic Syndrome NCT00074451 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Epidemiology of Stress and the Metabolic Syndrome NCT00073775 | University of Florida | — |
| Completed | Randomized Study of the Effect of Decreased Hyperinsulinemia on the Ovulatory Response to Clomiphene Citrate i NCT00005654 | National Center for Research Resources (NCRR) | N/A |
| Completed | Randomized Study of Decreased Hyperinsulinemia on the Ovulatory Response to Clomiphene Citrate in Women With P NCT00005104 | National Center for Research Resources (NCRR) | N/A |
| Completed | Short Term Study of Recombinant Human Insulin-like Growth Factor I in Children With Hyperinsulinism NCT00004825 | FDA Office of Orphan Products Development | N/A |
| Completed | Dose Ranging Study of Recombinant Human Insulin-like Growth Factor I in Children With Hyperinsulinism NCT00004699 | Children's Hospital of Philadelphia | N/A |
| Completed | Phase II Long Term, Randomized Study of Recombinant Human Insulin-like Growth Factor I in Children With Hyperi NCT00004700 | Children's Hospital of Philadelphia | Phase 2 |
| Completed | Diet, Insulin Resistance, and Cardiovascular Risk NCT00005530 | University of South Carolina | — |
| Completed | Lipoprotein Metabolism in Hypertensive African-Americans NCT00005709 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Insulin, Androgen, and Risk in African-American Women NCT00005380 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Central Obesity and Disease Risk in Japanese Americans NCT00005365 | University of Washington | — |