Clinical Trials Directory

Trials / Conditions / High-grade B-cell Lymphoma

High-grade B-cell Lymphoma

64 registered clinical trials studyying High-grade B-cell Lymphoma31 currently recruiting.

StatusTrialSponsorPhase
Not Yet RecruitingLong-term Study to Evaluate Safety and Persistence of GF-CART01
NCT06985576
GenomeFrontier Therapeutics TW Co., Ltd.
Not Yet RecruitingNeurocognitive Assessment in Adults Undergoing CD19 Targeted CAR-T Cell Therapy
NCT07463781
Fondazione Italiana Linfomi - ETS
Not Yet RecruitingTPG: Tafasitamab, Polatuzumab Vedotin, and Glofitamab as First-line Therapy for Diffuse Large B-cell Lymphoma
NCT07502872
Brown UniversityPhase 2
Not Yet RecruitingRituximab (Rtx) + Tafasitamab in Combination With Allogeneic NK Cells for Treatment of Relapsed/Refractory (r/
NCT07225439
Paolo Caimi, MDPhase 1
RecruitingGene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)
NCT06533579
Vironexis Biotherapeutics Inc.Phase 1 / Phase 2
RecruitingExploring the Clinical Impact of MYC Aberrations and Their Relationship With Microenvironment in Diffuse Large
NCT06588205
Fondazione Italiana Linfomi - ETS
RecruitingA Study of Glofitamab-based Treatment in People With Diffuse Large B-cell Lymphoma
NCT06765317
Memorial Sloan Kettering Cancer CenterPhase 2
RecruitingCLIC-2201 for the Treatment of Relapsed/Refractory B Cell Malignancies
NCT06208735
British Columbia Cancer AgencyPhase 1
RecruitingA Study of Circulating Tumor DNA (ctDNA) Testing for People With B-Cell Lymphoma
NCT06736613
Memorial Sloan Kettering Cancer CenterPhase 2
RecruitingctDNA-guided Therapy Optimization in Newly Diagnosed DLBCL
NCT06693830
Hua-Jay J Cherng, MDN/A
RecruitingSynKIR-310 for Relapsed/Refractory B-NHL
NCT06544265
Verismo TherapeuticsPhase 1
RecruitingEpcoritamab-CAR T Cells for Large B-cell Lymphomas
NCT06458439
Abramson Cancer Center at Penn MedicinePhase 2
RecruitingEmapalumab Prevention of CAR-T Cell Associated Toxicities
NCT06550141
Marcela V. Maus, M.D.,Ph.D.Phase 2
RecruitingImmunotherapy in Lymphoma
NCT06796517
Sung-Soo Park
RecruitingMosunetuzumab With Chemotherapy for the Treatment of Patients With Untreated C-Myc Rearrangement Positive High
NCT06249191
OHSU Knight Cancer InstitutePhase 1 / Phase 2
RecruitingT-Cell Therapy (EB103) in Adults With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (NHL)
NCT06343311
Estrella Biopharma, Inc.Phase 1 / Phase 2
RecruitingTesting the Combination of Anti-cancer Drugs Mosunetuzumab, Polatuzumab Vedotin, and Lenalidomide for the Trea
NCT06015880
National Cancer Institute (NCI)Phase 1
RecruitingP-CD19CD20-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With B Cell Malignancies
NCT06014762
Poseida Therapeutics, Inc.Phase 1
CompletedAdaptive Bridging RT in R/R B-cell Lymphoma (Pre-CAR T)
NCT06004167
Massachusetts General HospitalN/A
RecruitingEpcoritamab (Epcor)-Containing Combination Salvage Therapy Followed by ASCT & Epcor Consolidation in Patients
NCT06287398
Australasian Leukaemia and Lymphoma GroupPhase 2
Active Not RecruitingRelmacabtagene Autoleucel As Second-Line Therapy in Adult Patients with Aggressive B-cell NHL
NCT06093841
Shanghai Ming Ju Biotechnology Co., Ltd.Phase 2
RecruitingCD79b-19 CAR T Cells in Non-Hodgkin Lymphoma
NCT06026319
Marcela V. Maus, M.D.,Ph.D.Phase 1
RecruitingStudy Adding Drugs to Usual Treatment for Large B-Cell Lymphoma That Returned or Did Not Respond to Treatment
NCT05890352
SWOG Cancer Research NetworkPhase 2
Not Yet RecruitingOmic Technologies Applied to the Study of B-cell Lymphoma for the Discovery of Diagnostic and Prognosis Biomar
NCT05834426
Sociedad de Lucha Contra el Cáncer del Ecuador
RecruitingA Study to Evaluate the Pharmacokinetics and Safety of Loncastuximab Tesirine in Participants With Relapsed or
NCT05660395
ADC Therapeutics S.A.Phase 1
RecruitingStudy of SGR-1505 in Mature B-Cell Neoplasms
NCT05544019
Schrödinger, Inc.Phase 1
Active Not RecruitingLow Dose Radiation as Bridging Therapy in Relapsed B-Cell Non-Hodgkin Lymphoma
NCT05621096
University of NebraskaPhase 1
Active Not RecruitingStudy of 19(T2)28z1xx TRAC-Chimeric Antigen Receptor (CAR) T Cells in People With B-Cell Lymphoma
NCT05757700
Memorial Sloan Kettering Cancer CenterPhase 1
RecruitingTafasitamab, Retifanlimab, and Rituximab in Combination With Standard Therapy for the Treatment of Diffuse Lar
NCT05455697
University of WashingtonPhase 1 / Phase 2
RecruitingAcalabrutinib Maintenance for the Treatment of Patients With Large B-cell Lymphoma
NCT05256641
Jonsson Comprehensive Cancer CenterPhase 1 / Phase 2
RecruitingACE1831 in Adult Subjects With Relapsed/ Refractory CD20-expressing B-cell Malignancies
NCT05653271
Acepodia Biotech, Inc.Phase 1
Active Not RecruitingMosunetuzumab in Combination With Platinum-Based Salvage Chemotherapy in Patients With Relapsed/Refractory Agg
NCT05464329
Washington University School of MedicinePhase 1
RecruitingMosunetuzumab Consolidation Therapy After autoSCT in r/r Aggressive B Cell Lymphoma
NCT05412290
Washington University School of MedicinePhase 1
Active Not RecruitingSepantronium Bromide for the Treatment of High-grade B-cell Lymphoma
NCT05263583
Cothera Bioscience, IncPhase 2
TerminatedCopanlisib With Dose-Adjusted EPOCH-R in Relapsed and Refractory Burkitt Lymphoma and Other High-Grade B-cell
NCT04933617
National Cancer Institute (NCI)Phase 1
Active Not RecruitingA Multicentre, Parallel Arm, Open-label Trial of Frontline R-CHOP/Pola-RCHP and Glofitamab in Younger, Higher
NCT04914741
Peter MacCallum Cancer Centre, AustraliaPhase 1 / Phase 2
SuspendedPh I/II Study of E7777 Prior to CAR-T for R/R LBCL
NCT04855253
Masonic Cancer Center, University of MinnesotaPhase 1 / Phase 2
UnknownTislelizumab in Combination With Lenalidomide in Refractory and Relapsed Elderly Patients With Non-GCB DLBCL
NCT04796857
Huiqiang HuangPhase 1 / Phase 2
CompletedImmune Responses to COVID-19 Vaccination in Lymphoma Patients
NCT04858568
University Hospital Southampton NHS Foundation Trust
TerminatedRPM CD19-mbIL15-CAR-T Cells in Patient With Advanced Lymphoid Malignancies
NCT04844086
Eden BioCell Ltd.Phase 1
RecruitingA Study of AZD0486 in Subjects With B-Cell Non-Hodgkin Lymphoma
NCT04594642
AstraZenecaPhase 1
RecruitingStudy of Efficacy and Safety of CRC01 in Adult Large B-cell Lymphoma Patients
NCT04836507
Curocell Inc.Phase 1 / Phase 2
Active Not RecruitingAcalabrutinib and Anti-CD19 CAR T-cell Therapy for the Treatment of B-cell Lymphoma
NCT04257578
University of WashingtonPhase 1 / Phase 2
WithdrawnTelemedicine for Early Detection of Cytokine Release Syndrome and Neurotoxicity
NCT04503538
Wake Forest University Health SciencesN/A
CompletedFT596 With Rituximab as Relapse Prevention After Autologous HSCT for NHL
NCT04555811
Masonic Cancer Center, University of MinnesotaPhase 1
UnknownDLBCL Interim Response Evaluation for Customised Therapy
NCT04226937
Cambridge University Hospitals NHS Foundation Trust
Active Not RecruitingPolatuzumab Vedotin and Combination Chemotherapy for the Treatment of Previously Untreated Lymphoma
NCT04479267
Barbara Ann Karmanos Cancer InstitutePhase 2
Active Not RecruitingTrial of the Safety and Efficacy of Epcoritamab in Japanese Subjects With Relapsed or Refractory (R/R) B-Cell
NCT04542824
GenmabPhase 1 / Phase 2
UnknownCamrelizumab in Combination With Apatinib in Refractory and Relapsed DLBCL
NCT04476459
Huiqiang HuangPhase 1 / Phase 2
UnknownToripalimab Plus Rituximab Followed by R-CHOP for Elderly Patients With Untreated Diffused B Cell Lymphoma
NCT04058470
Huiqiang HuangPhase 1 / Phase 2
TerminatedFirst-in-Human (FIH) Trial of GEN3009 in Subjects With Relapsed or Refractory B-Cell Non-Hodgkin Lymphomas
NCT04358458
GenmabPhase 1 / Phase 2
RecruitingStudy of CAR-T Therapy in Older Patients
NCT04300998
Memorial Sloan Kettering Cancer Center
TerminatedAnakinra in Preventing Severe Chimeric Antigen Receptor T-Cell Related Encephalopathy Syndrome in Patients Wit
NCT04205838
Jonsson Comprehensive Cancer CenterPhase 2
Active Not RecruitingPembrolizumab in Combination With Chemotherapy for Patients With Untreated B Cell Lymphoma
NCT03995147
University of ChicagoPhase 2
UnknownDLCL002 Protocol for Patients With High Risk Aggressive B-cell Lymphoma
NCT03837873
Institute of Hematology & Blood Diseases Hospital, ChinaPhase 2
Active Not RecruitingNanochip Technology in Monitoring Treatment Response and Detecting Relapse in Participants With Diffuse Large
NCT03656835
Ohio State University Comprehensive Cancer CenterN/A
Active Not RecruitingDA-EPOCH-R Induction Followed by Nivolumab Consolidation in Newly Diagnosed MYC, BCL2 and/or BCL6 Rearranged H
NCT03620578
Stichting Hemato-Oncologie voor Volwassenen NederlandPhase 2
CompletedExploratory Study of CD19-targeted Chimeric Antigen Receptor T Cells(BZ019) for Relapsed and Refractory B-cell
NCT04067414
Institute of Hematology & Blood Diseases Hospital, ChinaPhase 1
CompletedA Study to Evaluate Safety, Pharmacokinetics, and Clinical Activity of Combination of RO6870810 and Venetoclax
NCT03255096
Hoffmann-La RochePhase 1
TerminatedCyclophosphamide and Alemtuzumab In Lymphoma
NCT03132584
Dana-Farber Cancer InstitutePhase 1
CompletedStudy of Venetoclax Plus DA-EPOCH-R for the Treatment of Aggressive B-Cell Lymphomas
NCT03036904
Weill Medical College of Cornell UniversityPhase 1
WithdrawnBrentuximab Vedotin, Bendamustine, and Rituximab in Patients With Relapsed or Refractory B-cell Non-Hodgkin Ly
NCT02623920
University of ArizonaPhase 2
CompletedRetrospective Analysis of Rituximab-containing Immunochemotherapy for Burkitt's or Burkitt-like Lymphoma in Ad
NCT01809600
Gachon University Gil Medical Center
CompletedTreatment for Advanced B-Cell Lymphoma
NCT01859819
New York Medical CollegePhase 2