| Recruiting | Prevalence of Symptomatic Gastroesophageal Reflux Disease in Czech Children (Czech GERDKids) NCT07482969 | University Hospital, Motol | — |
| Not Yet Recruiting | Association Between Obesity and Gastroesophageal Reflux Disease NCT07199582 | Assiut University | — |
| Recruiting | Comparison of Nissen-Sleeve and Gastric Bypass for GERD in Obese Patients NCT07158008 | Jagiellonian University | N/A |
| Recruiting | Gastrointestinal Dysmotility on Aspiration Risk NCT05455359 | Boston Children's Hospital | Phase 4 |
| Recruiting | The Effect of Inspiratory Muscle Training in People With Gastroesophageal Reflux Disease NCT07131397 | University of West Attica | N/A |
| Recruiting | The Effect of Postural Correction On Gastroesophageal Reflux Disease NCT06564558 | Cairo University | N/A |
| Unknown | Thresholds of SLR Maneuver in Obese Patients NCT06222177 | IRCCS Policlinico S. Donato | — |
| Recruiting | Validation of the C-mo System - Cough Monitoring NCT05989698 | Cough Monitoring Medical Solutions | N/A |
| Completed | Effect of Fermented Soybean (FSB) Supplementation on Gas-troesophageal Reflux Disease (GERD) NCT06524271 | NATTOME SDN BHD | N/A |
| Completed | A Study to Compare PK/PD Characteristics and Safety Profiles Between AD-212-A and AD-2121 NCT06025773 | Addpharma Inc. | Phase 1 |
| Recruiting | Esophageal and Gastric Registry and Biorepository NCT05180253 | University of Louisville | — |
| Unknown | Gastroesophageal Reflux Disease in the Dutch Population NCT05689918 | Radboud University Medical Center | — |
| Completed | Validation of HRM Score for the GERD Diagnosis NCT05851482 | IRCCS Policlinico S. Donato | N/A |
| Recruiting | Efficacy and Safety of EsoDuo® NCT06430047 | Chong Kun Dang Pharmaceutical | Phase 4 |
| Terminated | Systems Biology of Gastrointestinal and Related Diseases NCT05579444 | Viome | — |
| Unknown | ARMA (Antireflux Mucosa Ablation) in Patients With Chronic Refractory Reflux Disease NCT05425771 | Klinikum Garmisch-Patenkirchen | N/A |
| Completed | Esophageal pH-MII Duration: 12 or 24 Hours? NCT05760274 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Unknown | LPR Fluorescence Pilot NCT05204303 | The Functional Gut Clinic | — |
| Completed | The Effect of Using Virtual Reality Glasses on Post-Care Pain and Comfort Level in Intensive Care Patients NCT06923982 | Çankırı Karatekin University | N/A |
| Completed | Domiciliary Management of Dental Erosion in Patients With GERD With Biomimetic Hydroxyapatite NCT05371717 | University of Pavia | N/A |
| Recruiting | Anti-Reflux Endoscopic TX Using APC (AREA) in GERD Patients: (The AREA Study) NCT05570448 | Midwest Veterans' Biomedical Research Foundation | N/A |
| Unknown | Health, Economic Analysis and Clinical Aspects of Patients With Neurological Disabilities in Enteral Nutrition NCT05068089 | Bambino Gesù Hospital and Research Institute | — |
| Recruiting | Observational Registry of Transoral Incisionless Fundoplication (TIF) for Gastroesophageal Reflux Disease (GER NCT05066594 | IRCCS San Raffaele | — |
| Unknown | The Effect of Positional Therapy on Symptoms of Gastroesophageal Reflux Disease: A Prospective Pilot Study NCT04500288 | MetroHealth Medical Center | N/A |
| Unknown | Recovering Damaged Cells for Sequelae Caused by COVID-19, SARS-CoV-2 NCT04846010 | All Natural Medicine Clinic, LLC | Phase 1 / Phase 2 |
| Terminated | LINX Reflux Management System or Fundoplication Clinical Study in Patients With Hiatal Hernia >3 cm NCT04695171 | Foregut Research Foundation | — |
| Completed | Method of Early Diagnosis of Laryngopharyngeal Reflux NCT04771221 | Kazakh Medical University of Continuing Education | N/A |
| Terminated | Initiation of Acid Suppression Therapy Prospective Outcomes for Laryngomalacia NCT04614974 | Reema Padia | Phase 1 / Phase 2 |
| Recruiting | Efficacy Of Hiatal Closure For GERD NCT06280664 | University of Chicago | — |
| Unknown | PPI Therapy Impact on GERD After Sleeve Gastrectomy NCT04400136 | University of Roma La Sapienza | EARLY_Phase 1 |
| Completed | The Effect of Autonomic Modulation on Symptoms in Patients With Reflux Hypersensitivity NCT04253444 | Queen Mary University of London | N/A |
| Recruiting | Clinical Utility of WATS3D: A 5-Year Prospective Study NCT04312633 | CDx Diagnostics | — |
| Completed | Randomized Placebo-controlled Study of L. Reuteri NCIMB 30351 in GI Functional Disorders and Food Allergy in N NCT04262648 | NovoNatum Ltd | N/A |
| Unknown | Gastric Reflux and Sinonasal Symptoms NCT04105894 | Assiut University | — |
| Completed | Effect of a Combination Oral Formulation of Hyaluronic Acid, Chondroitin Sulphate and Magnesium Trisilicate in NCT04202692 | SOFAR S.p.A. | N/A |
| Terminated | Effect of CPAP on Abnormal Gastroesophageal Reflux and Lung Inflammation in IPF NCT05359965 | University of Arizona | N/A |
| Unknown | Image-Enhanced Endoscopy in the Gastrointestinal Tract NCT04085211 | King's College Hospital NHS Trust | — |
| Terminated | Effectiveness of Vonoprazan vs Omeprazole as Empiric Therapy for Gastroesophageal Reflux Disease (GERD) Patien NCT04028466 | St. Luke's Medical Center, Philippines | Phase 4 |
| Unknown | Pressure and Flow Study Before and After Treatments for EMD. The pFlow Study NCT03904004 | Fundacion Miguel Servet | — |
| Unknown | Japanese Upper GI Symptoms Compared With Iranian and Canadian Patients Presenting NCT03868267 | Hamilton Health Sciences Corporation | — |
| Completed | Bitter Tastants and Reflux NCT03777787 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Completed | Effect of a Combination of Hyaluronic Acid, Chondroitin Sulphate and Magnesium Trisilicate on Subjects With Ga NCT03883074 | SOFAR S.p.A. | N/A |
| Completed | Influence of Expiration Lente Prolongée on Gastro-oesophageal Reflux NCT03341585 | Vrije Universiteit Brussel | N/A |
| Unknown | The Bacterial Composition of the Stomach in Reflux Disease NCT03835663 | Imperial College London | — |
| Completed | Comparison Between Two Types of Sedation for Elective Upper Endoscopy Procedures NCT04410211 | University of Malaya | N/A |
| Unknown | Antireflux Mucosectomy (ARMS) for Treatment of Gastroesophageal Reflux NCT04194723 | Chinese University of Hong Kong | N/A |
| Completed | Post Prandial High Resolution Impedance- Manometry NCT03306485 | Hospices Civils de Lyon | — |
| Completed | Near Focus NBI-Driven Artificial Intelligence for the Diagnosis of Gastro-Oesophageal Reflux Disease NCT04268719 | King's College Hospital NHS Trust | — |
| Completed | Effectiveness of Physiologic Testing in PPI Non-Responders NCT03202537 | Northwestern University | EARLY_Phase 1 |
| Completed | Lower Esophageal Sphincter (LES) Stimulation in Patients With Ineffective Esophageal Motility NCT03476265 | Austrian Society Of Surgical Oncology | N/A |
| Unknown | Confocal Endomicroscopy for Permeability of Esophageal Wall in Refractory Gastroesophageal Reflux Disease (GER NCT03228407 | McGuire Research Institute | N/A |
| Suspended | Endoscopic Resection in Gastro-Esophageal Reflux Disease NCT03357809 | Hospital St. Joseph, Marseille, France | N/A |
| Completed | Effect of Citalopram on Reflux Episodes in Healthy Volunteers NCT03746691 | Universitaire Ziekenhuizen KU Leuven | Phase 4 |
| Active Not Recruiting | Transpyloric Feeding for Prevention of Micro-aspiration NCT03646045 | Nemours Children's Clinic | — |
| Completed | Effect of Magnesium Alginate in Infants With Gastroesophageal Reflux. NCT03881722 | Policlinico Hospital | Phase 3 |
| Recruiting | Endoscopic Bariatric Therapies (EBTs): A Retrospective and Prospective Multicenter Registry NCT04494048 | Weill Medical College of Cornell University | — |
| Completed | Effect of Right Lateral Position on Ventilated Preterm Neonates NCT03258528 | Ain Shams University | N/A |
| Completed | Antireflux Ablation Therapy (ARAT) for Gastroesophageal Reflux Treatment NCT03548298 | Coordinación de Investigación en Salud, Mexico | N/A |
| Unknown | Safety & Initial Efficacy of the LunGuard PFT Sys. on Enteral-Fed, Sedated and Mechanically Ventilated Patient NCT02609620 | LunGuard Ltd. | N/A |
| Recruiting | Endoscopic Fundoplication With MUSE System NCT03669874 | IRCCS San Raffaele | — |
| Completed | GERD Treatment With Transoral Incisionless Fundoplication (TIF) Following Hiatal Hernia Surgery NCT03143608 | Peter G Mavrelis | — |
| Enrolling By Invitation | Assessment of Esophageal Epithelium Integrity With Use of a Novel Mucosal Impedance Device NCT03103789 | Vanderbilt University Medical Center | — |
| Completed | Safety Study of Airway Clearance Techniques in Infants. NCT02128867 | Vrije Universiteit Brussel | N/A |
| Completed | Assessment of Gastro-esophageal Reflux Using Endo-Flip vs Bravo NCT00481949 | Guy's and St Thomas' NHS Foundation Trust | — |
| Completed | Observational Study (This Means That no Drug is Tested) in Patients Suffering of Gastroesophageal Reflux Disea NCT01601379 | Janssen-Cilag International NV | — |
| Completed | Observational Study of Anti-Reflux Surgery NCT01624506 | Torax Medical Incorporated | — |
| Completed | A Placebo Controlled Trial With Baclofen for the Treatment of GERD Patients With Incomplete PPI Response NCT03835442 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Completed | Partial Versus Total Fundoplication in the Surgical Repair of Para-esophageal Hernia. NCT04436159 | Karolinska University Hospital | N/A |
| Terminated | Evaluation of Esomeprazole in Treating Gastro-esophageal Reflux Disease (GERD) in Head and Neck Cancer Patient NCT00222079 | Douglas Trask | N/A |