| Not Yet Recruiting | Buprenorphine for Analgesia in Older Adults With Acute Fractures in the Emergency Department: a Randomized Con NCT07430345 | The Cooper Health System | Phase 1 / Phase 2 |
| Not Yet Recruiting | Clinical Validation of RBfracture for Diagnosing Trauma-related Musculoskeletal Injuries NCT07421791 | Radiobotics | — |
| Recruiting | Single Shot Exparel vs Catheters in Lower Extremity Trauma NCT07221019 | George Washington University | Phase 4 |
| Recruiting | Cannabidiol After Multi-Trauma for Pain and Opioid Therapy NCT06448923 | Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal | Phase 2 |
| Not Yet Recruiting | Immediate Fracture Risk After Antihypertensive Drug Initiation NCT06964217 | Ajou University School of Medicine | — |
| Enrolling By Invitation | LinkSymphoKnee (LSK) Total Knee Replacement System Study - Ultra-congruent (UC) NCT06670651 | LinkBio Corp. | — |
| Not Yet Recruiting | Surgical Treatment of Osteoarticular Infections Using Bioactive Bone Substitute NCT06402292 | Federal University of São Paulo | N/A |
| Completed | Effect of Bruxism on the Clinical Success of Posterior Composite Restorations NCT06881355 | Muğla Sıtkı Koçman University | — |
| Recruiting | Case Series on the Clinical Performance of VA Clavicle and Clavicle Hook Plate 2.7 Systems NCT04921865 | AO Innovation Translation Center | — |
| Recruiting | The PREVENT Trial: a Pragmatic Cluster Randomized Controlled Trial of a Multifaceted Fracture Prevention Model NCT04947722 | McMaster University | N/A |
| Unknown | Clinical Evaluation of Cast21 Short Arm Product During Treatment of Distal Radial or Distal Ulnar Fractures NCT06304649 | Cast21 | N/A |
| Active Not Recruiting | Metagenomic Next-Generation Sequencing for the Diagnosis of Fracture-related Infection NCT07256405 | Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer | — |
| Recruiting | Investigation Of Bioabsorbable Screws In Pediatric Orthopedic Surgery NCT06429267 | Louisiana State University Health Sciences Center in New Orleans | N/A |
| Completed | AI Assisted Detection of Fractures on X-Rays (FRACT-AI) NCT06130397 | Oxford University Hospitals NHS Trust | — |
| Withdrawn | Comparison of the Effectiveness of a Web Fracture Liaison Service (e_FLS) to Fracture Liaison Services in Fran NCT05303350 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Effects of PNF Technique in Children With Post Fracture Elbow Stiffness NCT06198088 | Riphah International University | N/A |
| Recruiting | PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation NCT05699174 | Major Extremity Trauma Research Consortium | Phase 3 |
| Unknown | Relationships Between Vitamin D and Orthopedic Trauma NCT04564625 | Methodist Health System | — |
| Unknown | Denosumab Treatment in CKD Patients at High Risk of Fracture NCT05692297 | Capital Medical University | N/A |
| Unknown | Wrist Arthroscopy During Surgical Treatment of Distal Radius Fractures NCT05580848 | Clinic for Orthopedics Lovran | N/A |
| Completed | The CHARM Study-Coordinating Transitions from Hospital for Older Adults with Fractures NCT06107699 | Horizon Health Network | N/A |
| Completed | The iCARE Study: Education Modules for Fracture Prevention NCT05445336 | McMaster University | — |
| Recruiting | Single-dose Intravenous Iron Therapy for Anemia After Orthopaedic Trauma NCT05292001 | Oregon Health and Science University | Phase 4 |
| Unknown | AI Performance for the Detection of Bone Fractures in Children NCT05538403 | University Hospital, Montpellier | — |
| Recruiting | Clinical and Radiological Outcomes of Medacta Shoulder System FR NCT05926622 | Medacta International SA | — |
| Recruiting | Pediatric Orthopaedic Implant Safety & Efficacy NCT05361980 | University of British Columbia | — |
| Withdrawn | Impact of Drugs on the Risk of Falls in the Fracture Department of the Paris Saint-Joseph Hospital Group NCT04470895 | Fondation Hôpital Saint-Joseph | — |
| Completed | Clinical Performance of Ceramic Laminate Veneers Made With Celtra Duo Press and IPS e.Max Press Ceramic NCT03713970 | Cairo University | N/A |
| Completed | Trial of Bilateral Sagittal Split Osteotomy Induced Paresthesia Using Ultrasonic vs. Reciprocating Saw Instrum NCT05205616 | University of California, San Francisco | N/A |
| Completed | Pilot Study on the Evaluation of the Effectiveness of a Virtual Reality Device on Anxiety During Procedural Se NCT04936880 | Poitiers University Hospital | N/A |
| Terminated | FastFrame Knee Spanning and Damage Control Kit PMCF NCT04730739 | Zimmer Biomet | N/A |
| Unknown | Bone Toxicity Following Pelvic Radiotherapy NCT04555317 | The Christie NHS Foundation Trust | N/A |
| Active Not Recruiting | COcoa Supplement and Multivitamin Outcomes Study: Effects on Falls and Physical Performance NCT05232669 | Brigham and Women's Hospital | N/A |
| Unknown | The Impact of Lower Limb Fractures on Body Mass Index (BMI) NCT05162521 | Kuwait Institute for Medical Specialization | — |
| Completed | Post-Stroke Osteopathy NCT04845269 | VASCage GmbH | — |
| Withdrawn | Influence of Verticalization on Bone Mineral Density and Biological Parameters of Bone Remodeling in Children NCT04761666 | Centre Hospitalier Universitaire, Amiens | — |
| Unknown | Treatment of Fracture Related Infection in Latin America. NCT05467644 | Manoel Victorino Hospital | — |
| Active Not Recruiting | Clinical and Radiological Outcomes of Medacta Shoulder System (BE) NCT05002335 | Medacta International SA | — |
| Completed | Clinical Validation of Boneview for FDA Submission NCT04532580 | Gleamer | — |
| Unknown | Posterior Implant-Supported Modified Monolithic Zirconia and Metal-Ceramic Single Crowns: 5 Years Study NCT04355325 | Jordan University of Science and Technology | N/A |
| Withdrawn | Dialectical Behavioral Therapy in High Risk OrthopaedicTrauma Patients NCT03776929 | Dartmouth-Hitchcock Medical Center | N/A |
| Recruiting | Intranasal Dexmedetomidine Plus Ketamine for Procedural Sedation NCT04195256 | Naveen Poonai | Phase 2 / Phase 3 |
| Terminated | Wright Foot & Ankle Post-Market Observational Study NCT04118894 | Stryker Trauma and Extremities | — |
| Completed | Wrist Fracture Evaluation With a Desktop Orthopedic Tomosynthesis System NCT03993691 | University of North Carolina, Chapel Hill | N/A |
| Unknown | Prevalence and Risk Factors for Common Diseases NCT04091035 | Anna Nordström | — |
| Completed | Influenza Vaccination Against Infectious Complications and Mortality in Older Adults With Fractures: a Large-s NCT07231016 | Taipei Medical University Hospital | — |
| Unknown | Early Mobilisation in the Surgical Robot Assisted Spinal Surgery NCT04133103 | Beijing Jishuitan Hospital | N/A |
| Completed | Question Prompt List for Orthopaedic Conditions NCT03912168 | Stanford University | N/A |
| Completed | Soft Part Management for Surgical Fractures of the Lower Limb NCT03915223 | University Hospital, Clermont-Ferrand | N/A |
| Completed | Anti-fibrinolytic and Anti-inflammatory Effects of Local Infiltration of Tranexamic Acid in Patients With Calc NCT05598086 | Hebei Medical University Third Hospital | N/A |
| Unknown | Normative Database for HR-pQCT-Based Radius and Tibia Strength NCT03219099 | Insel Gruppe AG, University Hospital Bern | — |
| Active Not Recruiting | Clinical and Radiological Outcomes of Medacta Shoulder System NCT03547947 | Medacta International SA | — |
| Terminated | Clinical Evaluation of the TITAN™ Total Shoulder System NCT03245320 | Smith & Nephew, Inc. | — |
| Completed | Early Mobilization of Spiral Metacarpal Fractures Compared With Operative Treatment NCT03067454 | Uppsala University | N/A |
| Unknown | Safety and Exploratory Efficacy Study of UCMSCs in Patients With Fracture and Bone Nonunion NCT02815423 | South China Research Center for Stem Cell and Regenerative Medicine | Phase 1 / Phase 2 |
| Completed | Optimal Vitamin D3 Supplementation Strategies for Acute Fracture Healing NCT02786498 | University of Maryland, Baltimore | Phase 2 |
| Completed | Thermal Imaging Compared to Skeletal Survey in Children Below 2 Years NCT04237454 | Sheffield Children's NHS Foundation Trust | N/A |
| Withdrawn | Regional Anaesthesia for Painful Injuries After Disasters NCT02698228 | Epicentre | Phase 4 |
| Completed | Surgical Treatment of Low Energy Pelvic Fractures in the Elderly NCT02591043 | University Hospital, Basel, Switzerland | N/A |
| Recruiting | Fragility Fracture Liaison Service and Anti-osteoporosis Medication Monitoring Service Study NCT02635022 | National Taiwan University Hospital | — |
| Completed | A Skills-Based Program Delivered Via Secure Live Video to Patients With Acute Musculoskeletal Trauma NCT03405610 | Massachusetts General Hospital | N/A |
| Completed | Platelet Rich Plasma Injection in Pilon Fractures NCT02481869 | University of Missouri-Columbia | N/A |
| Withdrawn | Early Range of Motion in 5th Metacarpal Fracture NCT02441790 | McMaster University | N/A |
| Unknown | Diffusion MRI and Growth Plate Injuries: Pilot Study NCT01774539 | University of British Columbia | — |
| Unknown | Outcome of Rehabilitation Following Internally Fixed Ankle Fractures NCT02160197 | Countess of Chester NHS Foundation Trust | N/A |
| Active Not Recruiting | Anti-osteoporosis Medication Monitoring and Management Service NCT02194647 | National Taiwan University Hospital | — |
| Completed | Osteoporosis and Fall Prevention High Risk Population Intervention and Follow up in the Metropolitan Area NCT02608749 | National Taiwan University Hospital | N/A |
| Completed | A Novel Selective Block of the Suprascapular Nerve NCT02035774 | University Hospital of North Norway | Phase 4 |
| Active Not Recruiting | Fragility Fracture Liaison Service Project NCT02194660 | National Taiwan University Hospital | — |
| Unknown | Effects of Etomidate on Postoperative Circadian Rhythm Changes of Salivary Cortisol in Children NCT02013986 | Du yi | Phase 4 |
| Completed | Single Shot Versus OnQ Pump in Extremity Fractures NCT02280291 | NYU Langone Health | Phase 4 |
| Completed | Mobile Device to Help FRAX® Screening NCT01930656 | National Taiwan University Hospital | — |
| Completed | Geriatric Health Exam Osteoporosis Screening NCT01934387 | National Taiwan University Hospital | — |
| Completed | Bisphosphonate Therapy in MONA Spectrum Disorder NCT02823925 | Medical University Innsbruck | — |
| Completed | Arcos Revision Stem: Evaluation of Clinical Performance NCT01820611 | Zimmer Biomet | — |
| Active Not Recruiting | Effectiveness and Cost-effectiveness of Surgical Treatment of Humeral Shaft Fractures. Randomized Controlled T NCT01719887 | Töölö Hospital | N/A |
| Unknown | Ibuprofen Versus Codeine. Is One Better for Post-operative Pain Relief Following Reduction of Paediatric Forea NCT01605240 | University of Manitoba | N/A |
| Unknown | Imaging Parameters to Predict Future Vertebral Fracture in Osteoporosis NCT01653873 | National Taiwan University Hospital | — |
| Completed | The Impact of Telemedicine on Orthopaedic Trauma Patients With Closed Fractures NCT01991782 | Vanderbilt University | N/A |
| Unknown | Tranexamic Acid in Orthopaedic Trauma Surgery NCT02080494 | University of Tennessee | N/A |
| Completed | Study to Find the Dose of Rapidly Administered Ketamine for Brief Painful Procedures in Children NCT01669642 | Washington University School of Medicine | N/A |
| Completed | Ketamine-propofol Versus Ketamine Alone for Procedural Sedation in Adults NCT01544725 | Centre Hospitalier Universitaire de Nice | Phase 4 |
| Unknown | Adequacy of Pain Management for Upper Extremity Fracture After Discharge From a Pediatric Emergency Depart NCT01514097 | Children's Hospitals and Clinics of Minnesota | — |
| Unknown | To Investigate the Effect of Early Community-care Program on Fracture Hip Patient NCT01537523 | Hong Kong Healthcare Volunteer Organization | N/A |
| Completed | Vibration in Boys With a History of Fracture NCT04241432 | Sheffield Children's NHS Foundation Trust | N/A |
| Completed | Evaluation of Treatment of Fractures of the Humerus With a Plate. NCT00408291 | University of Aarhus | — |
| Completed | MaxAn Post Market Surveillance Validation NCT01343693 | Zimmer Biomet | — |
| Completed | Polymorphisms in the Vitamin D System and Health NCT01395303 | University of Tromso | — |
| Terminated | Subcapital and Shaft Fractures of the 5. Metacarpal NCT01242982 | St. Olavs Hospital | N/A |
| Completed | Multi Centre Study on TESS V2 Shoulder System NCT03431857 | Zimmer Biomet | — |
| Completed | Osteogenic Profiling of Normal Calvarial Bone NCT02933359 | University of Pittsburgh | — |
| Terminated | Bone to Skin Thickness Study: Obese Versus Normal Population NCT01248182 | University of Mississippi Medical Center | — |
| Unknown | Surgical Treatment Versus Non-surgical Treatment of Ulnar Fractures NCT01123447 | University of Calgary | N/A |
| Completed | Risk Taking and Fracture Study NCT01768598 | Canadian Institutes of Health Research (CIHR) | — |
| Completed | Develop and Validate Ultrasonic Device for Osteoporotic Fracture Risk Assessment NCT01123421 | Artann Laboratories | — |
| Suspended | Lymphomyosot for Ankle Edema Following Fracture NCT00884988 | Shaare Zedek Medical Center | Phase 2 |
| Withdrawn | Fracture Evaluated in Emergency Room by Ultra Sound NCT01071733 | University of Aarhus | — |
| Unknown | NovaLign Intramedullary Fixation System (IFS) for the Treatment of Humeral Fractures NCT00969839 | NovaLign Orthopaedics, Inc | Phase 4 |
| Unknown | Pre-drilling or Self Drilling External Fixation Pins NCT01046747 | Temple University | N/A |
| Completed | Methadone Versus Morphine for Orthopedic Surgery Patients NCT00892606 | University of Louisville | Phase 4 |
| Completed | Do Aromatase Inhibitors (AIs) Decrease Intestinal Calcium Absorption? NCT00766532 | University of Wisconsin, Madison | Phase 4 |
| Completed | Management of Bone Defects Around the Elbow NCT00873145 | Medical University of Vienna | — |
| Terminated | A Geriatric Home Visit Program to Reduce Post-Hip Fracture Complications NCT02058329 | Northwell Health | N/A |
| Completed | Bone Microarchitecture in Women With and Without Fracture NCT01049191 | University of Wisconsin, Madison | — |
| Completed | Forteo for the Treatment of Unexplained Osteoporosis in Premenopausal Women NCT00697463 | Columbia University | Phase 2 / Phase 3 |
| Completed | Rest Easy: Is Bed Rest Really Necessary After Surgical Repair of an Ankle Fracture? NCT00690651 | The Alfred | N/A |
| Suspended | Assessment of Cortical Plasticity Following Short Term Limb Immobility NCT00647374 | Hadassah Medical Organization | — |
| Completed | RCT on Ketorolac and Tramadol in Bone Fractures Pain of Child NCT00560443 | IRCCS Burlo Garofolo | Phase 4 |
| Recruiting | Exactech Shoulder Post Market Clinical Follow-up Study NCT05603728 | Exactech | — |
| Completed | Anatomical Shoulder™ Fracture PMCF Study NCT02465398 | Zimmer Biomet | N/A |
| Completed | Early Application of Pulsed Electromagnetic Field in the Treatment of Postoperative Delayed Union NCT01574833 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | Phase 4 |
| Completed | Fractures Stratified by HIV and Antiretroviral Therapy (ART) Status NCT01077557 | ViiV Healthcare | — |
| Unknown | Treatment of Non-Dislocated Midshaft Both-Bone Fractures NCT00314600 | Colaris, Joost, M.D. | N/A |
| Unknown | Dislocated Unstable Distal Both-Bone Forearm Fractures in Children NCT00398268 | Colaris, Joost, M.D. | N/A |
| Terminated | Bone Physiology & Mechanics in Osteomyoplasty Amputation Rehabilitation NCT00271362 | VA Office of Research and Development | N/A |
| Unknown | Treatment of Unstable Both-Bone Midshaft Forearm Fractures in Children NCT00314587 | Colaris, Joost, M.D. | N/A |
| Unknown | Dislocated Stable Distal Both-Bone Forearm Fractures in Children NCT00397852 | Colaris, Joost, M.D. | N/A |
| Unknown | Undislocated Distal Both-Bone Forearm Fractures in Children NCT00397995 | Colaris, Joost, M.D. | N/A |
| Unknown | Treatment of Stable Both-Bone Midshaft Forearm Fractures in Children NCT00398242 | Colaris, Joost, M.D. | N/A |
| Completed | Study Comparing Plate Stabilization to Conservative Treatment in Midshaft Clavicle Fractures NCT01199653 | Helsinki University Central Hospital | Phase 2 / Phase 3 |
| Completed | Percutaneous Vertebroplasty Versus Conservative Treatment of Pain NCT00203554 | University of Aarhus | N/A |
| Unknown | Smoking Cessation Intervention in Acute Orthopedic Surgery NCT00704015 | Karolinska Institutet | N/A |
| Completed | Acute Pediatric Fracture Analgesia Study NCT00520442 | Medical College of Wisconsin | N/A |
| Completed | Racial and Ethnic Disparities in Acute Pain Control NCT00115180 | Agency for Healthcare Research and Quality (AHRQ) | — |
| Terminated | New Method for Distal Interlocking of Cannulated Intramedullary Nails NCT00648479 | Hadassah Medical Organization | Phase 1 / Phase 2 |
| Withdrawn | Computerized Tomography to Help Diagnosis Pediatrics Scaphoid Fractures. NCT00292006 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Phase 1 |