| Not Yet Recruiting | Verification of a New Predictive Delirium Score in Adults With Elective Cardiac Valve or Bypass Surgery With P NCT07276503 | University Hospital Tuebingen | — |
| Not Yet Recruiting | Transcutaneous Auricular Vagus Nerve Stimulation for Prevention of Emergence Agitation and Delirium in Childre NCT07394647 | The First Affiliated Hospital of Zhejiang Chinese Medical University | N/A |
| Recruiting | Dexmedetomidine-Midazolam vs. Ketamine-Midazolam on Emergence Delirium NCT07427446 | Kasr El Aini Hospital | Phase 4 |
| Recruiting | Efficacy of Ultrasound-guided Greater Auricular Nerve Block in Preventing Postoperative Emergence Agitation in NCT07435675 | Fayoum University | N/A |
| Recruiting | MELAtonin for Prevention of Postoperative Agitation and Emergence Delirium in Children NCT05541276 | Rigshospitalet, Denmark | Phase 3 |
| Recruiting | Remimazolam and Emergence Delirium in Pediatrics NCT07046364 | Peking University First Hospital | Phase 4 |
| Not Yet Recruiting | Quantitative Neurofeedback Techniques for Treating Perioperative Cognitive Disorders in Elderly Patients NCT06752148 | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | N/A |
| Active Not Recruiting | Nebulized Dexmedetomidine for Post-Anesthesia Delirium in Preschool Children NCT06761092 | Udayana University | Phase 4 |
| Not Yet Recruiting | Low Flow Anesthesia in Children Undergoing Strabismus Surgery NCT06560268 | Cukurova University | Phase 4 |
| Recruiting | Intraoperative Diagnosis of Neurocognitive Complications Via Electroencephalographic Analysis NCT06545786 | Federal Research and Clinical Centre of Intensive Care Medicine and Rehabilitology | — |
| Completed | Dexmedetomidine-esketamine Combined Nasal Administration and Emergence Delirium NCT06566469 | Peking University First Hospital | Phase 4 |
| Withdrawn | Mitigation of Emergence Agitation Through Implementation of Masimo Bridge Therapy NCT06387953 | University of Washington | N/A |
| Recruiting | Ketofol Versus Dexmedetomidine for Prevention of Emergence Delirium in Pediatric Patients Undergoing Squint Su NCT06545890 | Cairo University | Phase 1 / Phase 2 |
| Completed | Emergence Agitation Between Dexmedetomidine and Sevoflurane Anesthesia NCT06482125 | Pelita Harapan University | N/A |
| Completed | The Effects of Familiar Toy and Parental Presence Combination on Perioperative Pediatric Anxiety NCT06459089 | Karaman Training and Research Hospital | — |
| Not Yet Recruiting | Temperature Management on Postoperative Delirium NCT06406257 | Wang Hongjian | N/A |
| Recruiting | Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery NCT06326983 | Boston Children's Hospital | N/A |
| Completed | Emergence Agitation of Sevoflurane in Pediatric NCT06830564 | Ain Shams University | Phase 2 / Phase 3 |
| Recruiting | Nebulized Dexmedetomidine Combined With Ketamine Versus Nebulized Dexmedetomidine for Cleft Palate NCT05821972 | Assiut University | Phase 4 |
| Recruiting | Language During Inhalational Induction NCT06324955 | Boston Children's Hospital | N/A |
| Unknown | Effect of Intravenous Nalbuphine and Magnesium Sulfate on Emergence Agitation in Pediatric NCT06306040 | Assiut University | Phase 3 |
| Completed | The Effect of 40 Hz Transcranial Stimulation on the Incidence of Emergence Delirium in Children NCT06493513 | Henan Provincial People's Hospital | N/A |
| Unknown | Remimazolam for Emergence Delirium Prevention in Patients Undergoing Rhinoseptoplasty, FESS or Septoplasty NCT06398275 | University Hospital of Split | Phase 2 |
| Unknown | Sevoflurane and Intravenous Anesthesia in Hypospadias Repair NCT06396468 | Benha University | N/A |
| Completed | The Effect of Anesthesia Depth Monitoring on Emergence Delirium in Pediatrics NCT06323616 | Istanbul University | N/A |
| Unknown | Comparison of Emergence Delirium: Remimazolam vs Sevoflurane Anesthesia NCT06214117 | Second Affiliated Hospital of Wenzhou Medical University | Phase 4 |
| Active Not Recruiting | Decreasing Emergence Delirium With Personalized Music NCT06236477 | Washington University School of Medicine | Phase 1 / Phase 2 |
| Unknown | Emergency Delirium in Pediatrics Undergoing Tonsillectomy and Adenoidectomy NCT06215768 | Esraa Abdel Azez Soltan Mohamed Zayed | EARLY_Phase 1 |
| Recruiting | The Occurrence of Emergence Agitation in Pediatric Strabismus Surgery NCT06035757 | Konkuk University Medical Center | Phase 4 |
| Recruiting | Effect of FPCA on Incidence of Emergency Delirium in Children After Surgery NCT06092671 | Second Affiliated Hospital of Wenzhou Medical University | N/A |
| Unknown | Impact of Anaesthesiology Management on Paediatric Emergence Delirium Incidence NCT04291820 | Brno University Hospital | N/A |
| Unknown | Effect of Ketamine/Midazolam Premedication Versus Pre-extubation Ketofol on Recovery Profile in Pediatrics Und NCT06010927 | Cairo University | Phase 4 |
| Unknown | The Effect of Binaural Sound on the Occurrence of Emergence Delirium in Children Undergoing Strabismus Surgery NCT05883280 | Seoul National University Hospital | N/A |
| Terminated | AGItated Patients Management: intraNASAL Midazolam vs Intramuscular Loxapine NCT05324852 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Recruiting | Frontal Alpha Asymmetry and Pediatric Emergence Delirium NCT05800639 | Gangnam Severance Hospital | — |
| Recruiting | Prognosis of Patients Who Presented With a State of Extreme Agitation. NCT05632419 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Comparing Ketamine and Fentanyl in Pediatric Tonsillectomy: Pain Control and Emergence Delirium Outcomes (KVFP NCT06630364 | Medipol University | Phase 4 |
| Unknown | Intravenous Dexmedetomidine for Emergence Delirium in Pediatric Patient NCT05813106 | Security Forces Hospital | Phase 4 |
| Unknown | An Observational Study of Emergence and Hypoactive Delirium After Anesthesia NCT05582005 | McGill University Health Centre/Research Institute of the McGill University Health Centre | — |
| Completed | Comparative Study Between Nebulised Dexmedetomidine and Nebulised Midazolam in Children Undergoing Lower Abdom NCT05872087 | Ain Shams University | Phase 1 |
| Completed | Ketamine Versus Dexmedetomidine for Prevention of Postoperative Delirium NCT05341154 | Huda Fahmy Mahmoud, PhD | N/A |
| Completed | Verbal Stimulation of Orientation on Emergence Agitation NCT05105178 | Seoul National University Hospital | N/A |
| Completed | Effect of Dexmedetomidine on Prevention of Postoperative Nausea and Vomiting in Children NCT05124067 | Tanta University | Phase 1 |
| Recruiting | The PREVENT AGITATION Trial II - Children ≤1 Year NCT05091242 | Rigshospitalet, Denmark | Phase 2 / Phase 3 |
| Completed | Postoperative Neurocognitive Dysfunction: Is There Any Place for Emergency Agitation: A Prospective Cohort Tri NCT04820595 | Negovsky Reanimatology Research Institute | — |
| Unknown | Positive Imagery Therapy and the Incidence of Emergence Reactions With the Use of Ketamine NCT04746079 | Mercy Health Ohio | N/A |
| Withdrawn | Acupuncture in Emergency Delirium After Tonsillectomy NCT04693390 | IRCCS Burlo Garofolo | N/A |
| Unknown | Remimazolam Reduces Emergence Delirium in Preschool Children Undergoing Laparoscopic Surgery by Sevoflurane An NCT04621305 | Second Affiliated Hospital of Wenzhou Medical University | Phase 4 |
| Completed | Incidence of Emergence Delirium in the PACU NCT04531020 | Brno University Hospital | — |
| Completed | Influence of Monitoring the Depth of General Anesthesia Upon the Incidence of PONV and Emergence Delirium in C NCT04466579 | University Hospital Ostrava | N/A |
| Unknown | The Effect of Pediatric Patient Temperament on Postoperative Outcomes NCT04224324 | Boston Children's Hospital | — |
| Completed | Namsos Anaesthesia Children Outcome Study NCT04292457 | Helse Nord-Trøndelag HF | N/A |
| Completed | Effects of Hypothermia on Delayed Neurocognitive Recovery (DNR): an Observational Trial Among Patients Undergo NCT03636074 | University of Padova | — |
| Unknown | The Efficacy and Safety of Tropisetron in Preventing Emergence Delirium NCT04027751 | Beijing Chao Yang Hospital | Phase 4 |
| Unknown | Effects of Virtual Reality on Perioperative Pediatric Anxiety NCT04043663 | Germans Trias i Pujol Hospital | N/A |
| Recruiting | Post Operative Cognitive Dysfunction After Breast Surgery NCT03774420 | University of Padova | — |
| Unknown | Post Operative Cognitive Dysfunction and Delirium After Spinal Surgery NCT03950557 | University of Padova | — |
| Unknown | Dexmedetomidine Versus Nalbuphine in Prevention of Emergence Agitation Following Adenotonsillectomy in Pediatr NCT04058899 | Ain Shams University | Phase 1 / Phase 2 |
| Completed | Effects of Remifentanil Infusion on Emergence Delirium After Dental Surgery in Children NCT04300374 | Erzincan University | — |
| Completed | A Study of Dexmedetomidine Pharmacokinetics for Preoperative Sedation NCT03800641 | Eye & ENT Hospital of Fudan University | Phase 4 |
| Completed | Intranasal Dexmedetomidine Versus Intranasal Midazolam for Emergence Delirium Prevention NCT04263844 | Indonesia University | Phase 4 |
| Completed | Methadone for Emergence Delirium in Children Undergoing Outpatient Strabismus Surgery NCT03778372 | Ochsner Health System | — |
| Completed | Epigenetics in PostOperative Pediatric Emergence Delirium NCT03787849 | University of Sao Paulo | N/A |
| Completed | KETODEX for Emergence Delirium in Children Undergoing Outpatient Strabismus Surgery NCT03779282 | Ochsner Health System | — |
| Unknown | Emergence Delirium and Recovery Time in Children NCT03330613 | Aydin Adnan Menderes University | N/A |
| Completed | Effect of Monochromatic Light on Incidence of Emergence Delirium in Children NCT03285243 | Baylor College of Medicine | N/A |
| Completed | EEG - Guided Anesthetic Care and Postoperative Delirium NCT03330236 | Yale University | N/A |
| Completed | The Association of Cardiac Ion Channel Related Gene Polymorphism and Prolonged QTc Interval After Endotracheal NCT03788564 | Yonsei University | — |
| Completed | Perioperative Effects of Operating Room Virtual Tour NCT03172182 | Seoul National University Bundang Hospital | N/A |
| Completed | The Effect of Magnesium Supplementation During General Anesthesia on the Quality of Postoperative Recovery in NCT03132701 | Seoul National University Hospital | N/A |
| Completed | Premedication With Intranasal Dexmedetomidine or Midazolam for Prevention of Emergence Agitation in Children NCT03171740 | Brasilia University Hospital | Phase 3 |
| Completed | Dexmedetomidine Reduces Emergence Delirium in Children Undergoing Tonsillectomy With Propofol Anesthesia NCT03131375 | Athens General Children's Hospital "Pan. & Aglaia Kyriakou" | Phase 2 / Phase 3 |
| Completed | Effect of Sugammadex vs. Neostigmine/Glycopyrrolate on Pediatric Emergence Delirium in Sevoflurane-rocuronium NCT03229486 | Pusan National University Yangsan Hospital | Phase 4 |
| Unknown | Effect of Music on Emergence Delirium NCT02999542 | University of Pretoria | N/A |
| Completed | Effect of Fentanyl on Emergence Delirium (ED) on Children Undergoing Adeno-tonsilectomy at Kenyatta National H NCT02753725 | University of Nairobi | N/A |
| Completed | How Common Are Sleep Disorders and Problems With Emergence From Anesthesia in Surgical Patients NCT02980549 | University of Wisconsin, Madison | — |
| Unknown | Magnesium Sulphate and Sevoflurane Induced Emergence Agitation in Children NCT01743144 | Cairo University | Phase 4 |
| Unknown | Effect Study of Parecoxib to Treat Emergence Delirium and Postoperative Pain NCT01221025 | First Affiliated Hospital, Sun Yat-Sen University | Phase 4 |
| Completed | Correlation Between Pain and Emergence Delirium After Adenotonsillectomy in Preschool Children NCT01096797 | San Gerardo Hospital | Phase 4 |
| Completed | Emergence Delirium in Children: Total Intravenous Anesthesia With Propofol and Remifentanil Versus Inhalationa NCT00885443 | University of British Columbia | N/A |