NCT03132701

The Effect of Magnesium Supplementation During General Anesthesia on the Quality of Postoperative Recovery in Children

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 66 (actual)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 2 Years – 7 Years
• Healthy volunteers: Accepted

Summary

Evaluation of prevention of emergence delirium and analgesic effect of magnesium on children

Detailed description

Children \< 8 years old who scheduled for elective opthalmic surgery are randomly assigned to Magnesium (Mg) group and control group. Before anesthetic induction, modified Yale Preoperative Anxiety Scale (m-YPAS) is assessed. Routine anesthetic induction is performed, and neuromuscular blocker is not used. Laryngeal mask airway is inserted and controlled ventilation is started. In Mg group, Mg of 30 mg/kg is administered for 10 minutes and then continuously infused (10mg/kg/hr) until 5 minutes before surgery end. In control group, the similar volume of saline is infused. Pediatric Anesthesia Emergence Delirium (PAED) scale and pain score (Modified Children's Hospital of Eastern Ontario Pain Scale, CHEOPS) will be measured immediately after and 30 minutes after surgery.

Conditions

• Emergence Delirium

Interventions

Type	Name	Description
DRUG	Magnesium	Mg is administered during anesthesia until 5 minutes before surgery ends
DRUG	Saline	Same volume of saline is infused until 5 minutes before surgery ends

Timeline

• Start date: 2017-06-08
• Primary completion: 2017-12-12
• Completion: 2017-12-12
• First posted: 2017-04-28
• Last updated: 2018-08-02

Locations

1 site across 1 country: South Korea