| Recruiting | Nirogacestat in Premenopausal Females With Desmoid Tumor/Aggressive Fibromatosis (DT/AF) NCT07176689 | SpringWorks Therapeutics, Inc. | Phase 4 |
| Active Not Recruiting | A Study of Nirogacestat in Japanese Adults With Desmoid Tumors/Aggressive Fibromatosis (DT/AF) NCT07170644 | SpringWorks Therapeutics, Inc. | Phase 2 |
| Active Not Recruiting | Familial Adenomatous Poliposys Italian Network (Rete Italiana Poliposi Adenomatosa Familiare) NCT07461246 | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | — |
| Not Yet Recruiting | A Prospective Clinical Study on the Safety and Efficacy of Radiofrequency Ablation for the Treatment of Patien NCT06355921 | Blokhin's Russian Cancer Research Center | N/A |
| Recruiting | Cryoablation Versus Medical Therapy in Desmoid Tumors Progressing After Watchful Waiting NCT06081400 | University Hospital, Strasbourg, France | N/A |
| Completed | Burden of Disease and Living Situation in Desmoid Patients NCT06258421 | Technische Universität Dresden | — |
| Recruiting | Study of Cryoablation and Nirogacestat for Desmoid Tumor NCT05949099 | Nam Bui | Phase 2 |
| Active Not Recruiting | A Study of AL102 in Patients With Progressing Desmoid Tumors NCT04871282 | Immunome, Inc. | Phase 2 / Phase 3 |
| Unknown | A Randomized, Double-blind,Phase Ⅲ Study of Liposome Doxorubicin in Desmoid Tumor NCT05561036 | Sun Yat-sen University | Phase 3 |
| Completed | Quality of Life of Patients With Desmoid-type Fibromatosis NCT04289077 | Erasmus Medical Center | — |
| Completed | Nirogacestat for Adults With Desmoid Tumor/Aggressive Fibromatosis (DT/AF) NCT03785964 | SpringWorks Therapeutics, Inc. | Phase 3 |
| Completed | A Study to Evaluate the Safety and Efficacy of Vactosertib and Imatinib in Patients With Advanced Desmoid Tumo NCT03802084 | Hyo Song Kim | Phase 1 / Phase 2 |
| Completed | Phase I, Open-label, Non-randomized Study to Evaluate Safety of BC2059 NCT03459469 | Iterion Therapeutics | Phase 1 |
| Completed | Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers NCT03190174 | Sarcoma Oncology Research Center, LLC | Phase 1 / Phase 2 |
| Completed | Studying Genes in Tissue Samples From Younger and Adolescent Patients With Soft Tissue Sarcomas NCT01567046 | Children's Oncology Group | — |
| Completed | MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors NCT02076906 | AeRang Kim | Phase 1 |
| Completed | A Pilot Study Evaluating the Use of mTor Inhibitor Sirolimus in Children and Young Adults With Desmoid-Type Fi NCT01265030 | MaineHealth | Phase 1 / Phase 2 |
| Completed | CT-guided Radioactive Iodine-125 Seed Implantation for Recurrent Desmoid Tumors NCT06195085 | Peking University Third Hospital | — |
| Completed | Study to Evaluate Imatinib in Desmoid Tumors NCT01137916 | Heidelberg University | Phase 2 |
| Completed | Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas NCT00474994 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Completed | Imatinib Mesylate in Treating Patients With Recurrent or Refractory Fibromatosis NCT00287846 | UNICANCER | Phase 1 / Phase 2 |
| Completed | Sulindac and Tamoxifen in Treating Patients With Desmoid Tumor NCT00068419 | Children's Oncology Group | Phase 2 |
| Completed | Radiation Therapy in Treating Patients With Aggressive Fibromatoses NCT00030680 | European Organisation for Research and Treatment of Cancer - EORTC | Phase 2 |
| Completed | Vinblastine and Methotrexate in Treating Children With Desmoid Tumors NCT00003019 | Children's Oncology Group | Phase 2 |
| Completed | Toremifene in Treating Patients With Desmoid Tumors NCT00002595 | Advocate Lutheran General Hospital | Phase 2 |
| Completed | A Cohort Study of Patients Treated With Brachytherapy for Selected Desmoid Patients in Gardner Syndrome NCT01286662 | Triemli Hospital | — |
| Available | Individual Patient Compassionate Use of Nirogacestat NCT05041036 | SpringWorks Therapeutics, Inc. | — |
| No Longer Available | Compassionate Use Protocol for PF-03084014 in Patients With Advanced Solid Tumor Malignancies NCT02955446 | University of Colorado, Denver | — |